A child is approached by a man, but manages to escape his attentions. Matteo's mother reports the incident to the Precinct and Commissioner Scalise immediately alerts his men. Roberto Ardenzi and Valeria discover that another child in the neighborhood, Tobia, has also been the victim of molestation, but the mother had not reported the incident and is reluctant to subject her son to the police's questions. A new report of pickpocketing arrives at the Precinct, this time Fast Boy has hit two Japanese tourists. From the stolen cell phone the pickpocket sends challenging messages to Inspector Belli. During a new stakeout by Mauro and Luca, in which Ugo also clumsily participates, Fast Boy manages to escape again. But Mauro does not give up, and following the trail of the stolen bib he finally manages to get his hands on the pickpocket, discovering with surprise that she is a girl.

Giovanna Scalise is busy with inspectors Manrico and Mauro Belli solving the strange case of a girl's kidnapping, while Luca and Valeria are on the trail of a thief who strikes in a movie theater. In the meantime, Ugo improvises as a computer expert, making Parmesan despair. Roberto and Angela are worried about little Maura who is sick. The person plotting to kill Scalise has an unexpected stroke of luck: her mother Caterina is taken ill and Federico calls the police station to ask for help, Saro is present while Luca gives the inspector's home address to the doctor.

Saro, increasingly under pressure from Vito Tonnara, begins to prepare the ambush... Mauro and Roberto, called to investigate a scam, discover with surprise that the robbed person is their elementary school teacher. Once the case is solved, they recall their school years with her and the teacher reveals funny details about them. Meanwhile, Manrico and Valeria are busy with a case involving a psychiatrist and one of his patients in the throes of a fit of rage; the attack will be foiled in extremis by Scalise and his men. Giovanna returns for dinner accompanied by Manrico, unaware of the mortal danger that awaits her outside her house.

Commissioner Scalise, unconscious on the ground after being hit by Saro, is rushed to the hospital, it would seem all lost for Giovanna and the child she is carrying... but a bulletproof vest, which the commissioner has decided to wear all the time since she knew she was pregnant, has worked a miracle. Manrico, to the amazement and anger of his colleagues and friends, is stopped and interrogated by the DIA as a presumed accomplice of the attacker. At the District, despite the tragic moment, the activity must continue. Mauro and Valeria are on the trail of a gang of boys who attacked and robbed a prostitute. Their investigations in an arcade will lead to the surprising identification of the leader of the gang.

Vito Tonnara advises Saro to disappear from circulation for a while, Saro is terrified of what he has done. Giovanna leaves the hospital as soon as she recovers to go to the DIA and intervene in defense of Manrico. To everyone's amazement she declares that Manrico cannot be guilty of complicity in the attack because he is the father of her child. Manrico is speechless. Meanwhile, the District is dealing with a very delicate case. Monti, a retired professor upset by the death of his son, locks himself in the class his child attended, kidnapping all the students. Mauro, Roberto and Luca intervene immediately and with Angela's help they manage to avoid dramatic consequences. There is a surprise visit for Valeria, her ex-boyfriend suddenly shows up at the District begging her to come back with him. Manrico will have to intervene to help his colleague.

Maddalena, Parmesan's niece, is found in a confused state outside a nightclub by Luca and Valeria, who are on patrol. She is rushed to the hospital, and it turns out that she is under the effects of a powerful drug and in danger of death. The entire District mobilizes to find those responsible for the incident, investigating the nightclub and the faculty attended by Maddalena. Meanwhile, Roberto, at Scalise's request, is dealing with a delicate case involving Irene, his colleague who is an expert in telecommunications and is being threatened and intimidated by her alcoholic ex-husband. Faithful to his instructions to observe maximum discretion, Roberto arouses the suspicions and jealousy of Angela, who thinks that her husband has a lover. After Scalise's return, the atmosphere at the District is very tense, everyone wants to find the culprit of the attack, especially Manrico, who cannot forgive himself for not being at Giovanna's side at that moment.

The District is busy with a murder case, the only witness is an autistic boy. While Giovanna, Manrico and Mauro investigate, Angela tries to communicate with the boy to get some clues. Roberto and Luca, on the other hand, are busy unmasking a magician's scam. Giovanna and Manrico, after the dramas and tensions, finally manage to clear things up and find their intimacy again. Both participate in the meeting of all the colleagues to organize the search for whoever attempted to kill Scalise.

Giovanna and her men are busy searching for the perpetrator of the attack she escaped. His identity is discovered: it is Saro. In the meantime Roberto discovers that his girlfriend is Laura and follows her. Her home is also identified and searched. The circle tightens... Meanwhile, the police station is dealing with a case of sexual harassment by a so-called agency that selects TV showgirls. Valeria responds to the ad and shows up for the audition, the true intentions of the "selectors" are immediately evident and Manrico and other officers rush to her aid, stopping the molesters. Luca is uncomfortable after the tensions following the attack and, tempted to leave the police station, he inquires about the procedures for becoming a private investigator.

Manrico tries to convince Giovanna to take a break, she is hesitant. The police station is dealing with a delicate case of kidnapping and blackmail of a bank manager, whose daughter is held hostage. For Mauro there are surprises, Paula is finally back, but the girl reacts badly to the fact that Tiberio has moved in with Mauro.

The 10th Tuscolano is dealing with a case involving the Chinese community of the capital and requiring environmental wiretaps and long shadowing involving all of Scalise's men. It seems that the owner of a Chinese restaurant has been kidnapped. On this occasion, Manrico and Mauro use technical means to continue their investigations on Saro, putting his girlfriend, Laura, under surveillance. Luca is preparing his resignation letter. However, the advanced pregnancy and the doctor's recommendations force Giovanna to follow the case from the police station, under the watchful eye of Manrico, who is very apprehensive. Giovanna is also anxious, she has not yet managed to confess to her family that she is pregnant.

The Chinese case turns out to be much more complex than expected, it is a real internal war between two mafia families with mysterious and disturbing implications. Meanwhile Luca and Valeria are dealing with a scam by a skilled door-to-door salesman, while their colleagues think of a farewell gift for Luca. Giovanna is still weakened by pregnancy-related disorders, while Mauro and Paula are in crisis again.

In a studio, Marico and Valeria discover the body of a photographer and near the body they find some red sequins. The investigation leads the two police officers to the home of a young couple, where they find the incriminating sequin dress: the two boys killed the photographer to rob him of a batch of marijuana. In the precinct Valeria realizes that she is not very loved by her colleagues and vents her anger with Giovanna who, in the meantime, has had to reveal to her mother that she is pregnant. The investigation into the Scalise attack continues and the circle tightens ever more around Saro who, having called his girlfriend Laura and given her a date, is followed by the precinct officers. Things between Mauro and Paula do not seem to be improving.

Sofia is a Romanian girl who was attacked. Vittoria and Mauro discover that behind the attack is a man who extorted fifteen million from the girl for a marriage that would give her Italian citizenship and thanks to the investigations, a real criminal organization also comes to light. Meanwhile in the district, Giovanna decides that Valeria would be perfect to meet Laura, Saro's girlfriend. Valeria, thanks to a stratagem, manages to meet Laura and, thanks to a series of clues, also discovers where the girl meets Saro: the place is a second-hand shop where the district agents will be able to arrest the attacker of Scalise. Finally, the reason that has put the relationship between Mauro and Paula in crisis seems to be the presence of Mauro's father, Tiberio, who lives in the house with them.

A dramatic story of jealousy involves two young people: long engaged, he does not accept the end of the love, and above all jealousy blinds him; the girl after some initial signs of violence from her ex reports him to the police of the district, but then reconsidering withdraws the complaint: this unfortunately will cost her life: her ex discovers her with her new lover stabs her; desperate he will attempt suicide but this time the officers will stop him. Giovanna confronts Saro, Manrico is close to her. Scalise would like to convince the boy to collaborate but to no avail. For the moment there is no evidence to arrest him and therefore they must release him, but the officers of the district are after him. In the meantime Paula asks Luca to investigate the seriousness of an airline that offers her a job as a hostess and asks Luca to keep this work appointment secret. Tiberio, in order not to weigh on the relationship between Mauro and Paula, decides to leave his son's house.

Saro and Laura are being watched. They want to escape and the girl, having learned from her boyfriend the whole truth about the attack, would still like to stay with him and escape; but Saro, having arrived at Laura's, is surprised by his future executioner: Vito Tonnara who kills him in cold blood in front of Laura and then escapes from the precinct officers. Later, Laura at the police station finally manages to identify Tonnara by giving a face to Scalise's persecutor. Meanwhile, in the precinct, Luca, following some investigations connected to a dog found at the end of its life, has discovered that a dog breeder is actually a crook who organizes clandestine fights, sending several animals to the slaughterhouse. Finally, Mauro is very angry with Paula who, having accepted the job at the airline as a hostess, must now leave for Milan.

Pablo the "Gitano" gets four days leave from Rebibbia prison and, in the company of his woman, steals a luxury sedan that he exchanges for a gun from a fence to rob a jewelry store. Mauro recognizes the robber following the jeweler's complaint: he was a childhood friend of his, Paolo Acerri, known as Pablo the Gitano. The boys of the district are now busy capturing him. Giovanna understands that she has become a personal target of Vito Tonnara who wants her dead to avenge the death of his son. Tonnara has been abandoned by the Sicilian dome, now he is a "loose cannon" who has nothing left to lose and will not find peace until he has killed Giovanna. Meanwhile, Parmesan and Ingargiola discover that Vittoria's boyfriend has a criminal record and would like to inform the girl of this. For Mauro and Paula things are not going well: he would like to spend more time with her who instead dedicates herself exclusively to work.

Mauro and Valeria finally manage to find Pablo the "Gitano"'s hideout, but with Mauro in handcuffs, he manages to escape with a hostage. Only later, after a tight chase, will the police be able to catch the criminal. Tonnara is in Rome and Scalise finds out about this. Meanwhile, Ingargiola forces Vittoria's criminal boyfriend to leave her alone: ​​she is desperate.

Professor Monti is on the terrace of a building in the throes of a suicidal crisis. Angela, who happens to be in the courtyard of this building, wants to help the man in the throes of a crazy crisis. Having reached the professor, everything seems under control when, a sudden and unexpected gesture surprises Angela who falls into the void in front of the eyes of her husband Roberto who is holding their daughter. Angela dies. In the meantime, Tonnara continues to spy on Giovanna Scalise, but there is news: she has two pistols well equipped with bullets.

Belli, saddened by the loss, decides to end his story with Paula. Meanwhile Tonnara, who has been monitoring the movements at the police station, intercepts Borsello and offers him a "deal".

Giovanna, very close to giving birth, discusses future prospects with Manrico. Tonnara is about to strike the final blow and Scalise is practically unprotected at the police station.

Commissioner Giulia Corsi is assigned to the tenth Tuscolano of Rome. Ardenzi has won the competition to become commissioner. A bank robber escapes due to an unforeseen event on a bus, on which Commissioner Corsi happens to be traveling.

A theft is reported and an officer's partner is suspected. Meanwhile, a man's body is discovered in a closed construction site. A recovered video reveals that Angela, Ardenzi's wife, was pushed and did not slip from the ledge.

An Eastern girl who works in a dry cleaner's is raped by her boss. Ardenzi discovers a clue by reviewing the film showing his wife's fall, but unwittingly ruins it. He decides to stay in Rome to investigate.

A teenager commits suicide. It is believed that the act was committed because of the sexual violence suffered by the boy at the hands of the owner of an arcade. Ardenzi searches for evidence on the terrace where the tragedy involving his wife occurred.

Ugo thinks he inherited from a relative. Corsi shoots in vain at a robber, seriously wounding a child playing in the street. Ardenzi tries to trace the owner of the ring worn by the man who pushed Angela.