The Mice must now face Limburger's latest machine from annihilating Mars. The machine attracts asteroids to the planet, to bring complete destruction.

The Biker Mice have to work double time to clear their names and save the mayor before Chief of Police Greasepit catches them.

When the Biker Mice finally capture Limburger, they must return with him to Mars to face trial. They discover that they are also thrown in prison for treason. The Mice have to escape and save Charley from Greasepit and Karbunkle while claiming that they have not done anything wrong.

Throttle, Modo and Vinnie...The Biker Mice from Mars...escape their planet as it it devastated by the fish faced plutarkians. Crashlanding in Chicago, the renegade rodents soon discover the Plutarkians next target: EARTH. Led by his supreme chessiness, Lawrence Limburger, and his devilish cohorts, Greasepit and the fiendish Dr. Karbunkle, the Plutarkians are already undermining the Windy City. It's tail whippin' time 'cause the baddest motorcycle mammajammers in the universe are riding to the rescue.

Limburger receives help from the Lugie Brothers, who are part of the Scum of the Universe. They must fumigate the city in an attempt to drive the citizens of Chicago out of town.

When Modo is covered in toxic substances, Limburger escapes with his bike. Modo does not want to rest while Charley and the guys rescue his bike.

The mice must travel back to the time of the dinosaurs to keep Chicago from disappearing before it was ever built.

Limburger hires Evil Eye Weevil to reign chaos on the town, causing mischief and mayhem and succeeds in driving the trio apart.

They still have to roost Napoleon Brie from Chicago where he's taken over in Limburger and the mice's absence.

Limburger's old Plutarkian rival, Napoleon Brie arrives on Earth to try and take over operations.

Charley and Karbunkle get whisked away when execs for a galactic company try to convince their boss that their pick is the better scientist.

Limburger has the unpleasant task of baby-sitting his nephew, who he manages to figure into his latest plan.

Limburger frames the mayor's kidnapping on the Biker Mice, so he can take over the city.

In order to steal all the steel from the town, Limburger offers Modo a new arm to work for him.

When intergalactic game hunters catch Modo's nephew Rimfire, he manages to escape in their ship and finds himself on Earth.

The Heavy Metal mouse that the mice despised on Mars, heads into Chicago, but with an all-new attitude.

The mice and Charley must race to save the Last Chance when Limburger manages to get the building legally condemned.

Limburger's incompetence finally lands him a demotion from the High Chairman. When the High Chairman appoints Greasepit in his place, he is able to capture The Last Chance garage.

Throttle's ladylove lands in Chicago to steal the last remaining specimen of a plant that is desperately needed for the Martian ecology to survive.

Limburger's latest villain manages to infect the mice's bikes, making them turn on their riders.

Dr. Karbunkle creates an inflation machine, which turns Greasepit into a giant. His perspective of Charley in a pile of Grease makes him fall in love with her. He brings her flowers, reads poetry to her, but she refuses at the end.

Two of the Biker Mice are injured when a new gang arrived in town, and stole all the gas.

Limburger's new plan is to literally cut the city free from the Earth and eject it to Plutark.

When the Plutarkian leaders are furious with Limburger for failing to capture the Last Chance Garage, he must prove himself worthy.

Limburger uses the gene scrambler to steal trees, while Karbunkle and Fred are caught in the gene scramblers rays and are scrambled together.