In Laceyville, PA, the town barber, Joe Colegrove, and his wife Marlene are thought to be perfect parents with a knack for raising strapping sons. But when half the family is slaughtered in their own beds, all eyes turn to the surviving kin.

In a wealthy suburb of San Diego, CA, a divorce attorney, Tim MacNeil, and his wife Doreen enjoy a charmed life with their two teenage children. When one family member is brutally murdered, a blood relative's diabolical conspiracy surfaces.

In Tucson, AZ, the churchgoing Sanchez family of six seems perfect. But when the decomposed body of one member is found in the desert, investigators find a killer living very close to home.

In Seminole, FL, police receive two frantic 911 calls from separate members of the Kyne family, each accusing the other of murder.

For the disciplined Kazigo family in Westchester County, NY, secrets bubble to the surface and all roads lead to murder. A hunt for the victim's body leads investigators to unmask one family member hell-bent on revenge.

In suburban Placentia, CA, the Jessee family does battle with cancer, never suspecting another killer lurks within their midst. With survivors pointing fingers at each other, police embark on an epic, decade-long murder investigation.

In the seaside town of Cary, NC, the Britt family lives a charmed existence until the housing market crashes, igniting a blaze of greed that will leave one family member dead and another behind bars.

In Tampa, FL, multimillionaire lottery winner, Jeffrey Dampier, is sharing the wealth with his extended family. But lady luck can be fickle, and this family's red-hot winning streak is soon to end in cold-blooded murder.

In the sleepy town of Bridgeville, DE, a beautiful autumn is interrupted by the mysterious disappearance of Billy Sproates and his uncle John Charbonneau. As investigators dig deeper, a family's disturbing secrets are revealed ... at the bottom of a shallow grave.

In the city of Rock Hill, SC, the Robertsons seems to have it all: wealth, success and two loving sons. No one suspects there are dark secrets locked within their home's brick walls or that one family member's greed will lead to murder.

When the quiet Connecticut town of Ledyard is shaken by the brutal murder of one of its most-colorful citizens, Buzz Clinton, investigators uncover a complex murder plot with a little girl at its dead center.

In the idyllic lakeside town of Nice, CA, Don and Mary Ann Duvardo seem to have it all: a dream home and three thriving children. But someone in the family is living a tangled web of lies. Soon, resentment and greed drive one blood relative to murder.

In idyllic Tifton, GA, the Evans family runs a charming flower shop and a successful trucking business and live seemingly perfect lives. But when infidelities threaten their bliss, desperate attempts to stick together end in murder.

In peaceful Green Gove Springs, FL, the Jones family lives the good life with a successful business and two beautiful daughters. But when a naive new houseguest finds skeletons in the closet, one family member will seek revenge by bloodshed. [also shown as S3:E2]

In the town of Libertyville, IL, Bruce and Darlene Rouse appear to have everything: wealth, success, and three wonderful children. But behind closed doors, a toxic mix of scorn, jealousy, and greed is about to boil over into a scene of shocking carnage. [also shown as S3:E1]

The Jackson family of Borger, Texas shares the same American values as their neighbors. But a dark family secret reveals at least one Jackson is a wolf in sheep's clothing poised to thin the flock by murder.

The forward-thinking Santaguida family enjoys a healthy, natural lifestyle in the hippie haven of Evergreen, CO. But when one family member is found brutally strangled, homicide detectives discover this peaceful image is all smoke and mirrors.

The Milo family's Arkon, OH, based cosmetics supply chain is one of the biggest in the country. But beauty is skin deep, and an integral fight for company control will expose an ugly underbelly of conspiracy, lies and murder.

The Allman sisters have deep roots in their tight-knit Oakland community. When drug dealers threaten the neighborhood, the family decides to stand their ground. But after their house goes up in flames, one family member hides a smoldering secret.

The Byrom family of Luka, MS, seem to have it all: love, success, and plenty of Southern charm. But they also have some very dark secrets. And soon, a penchant for sordid sex and a passion for poison will result in murder.

For the DeWilds of Edgewater, CO, family always comes first. But when one DeWild threatens to break that bond, the find the only way out of this family is murder.

With a Coral Gables mansion and membership to the local yacht club, life's a beach for accountants Ed and Maggie Locasio. But when suspicion and infidelity threatens to break family bonds, one family member will be hit by the death tax.

The Bautista family of Riverside, California is living the American dream with a nice home and two hard-working sons. But that dream will soon become a nightmare as one Bautista threatens to sever family ties and somebody loses their head.

For Starkville, MS, couple Joey and Kristi Fulgham, friends and family are one and the same. But when small town hospitality leads to dangerous liaisons, one family member decides the only way out is murder.

In the small town of Munster, IN, the Levine family real estate business is flying high. But life for these jetsetters is about to hit some turbulence as brotherly love turns into backstabbing, revenge and murder.