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Actor Ted Danson learns how human brains distinguish fact from fiction in a series of games.

Keegan-Michael Key welcomes billionaire CEO and reality star Mark Cuban ("Shark Tank") to the show.

Actors Kristen Bell and Dax Shepard face off in a series of Battle of the Sexes games designed to illustrate the differences between female and male brains.

Actors Anthony Anderson and Marsai Martin ("Black-ish) face off in a series of games with host Keegan-Michael Key.

Have you ever seen a ghost? Have you ever known something was going happen before it happened? If so, you may share a link with the paranormal. Or it might just be your brain playing tricks on you. Whether you're a skeptic or a believer in the supernatural, you have to admit there are things out there your brain just can't quite explain. This is an episode about your brain and the paranormal. Get ready for a series of games and experiments designed to prove you actually know more about the unknown than you think. We're going to put your sixth sense to the test by ...

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Actor-musician Jack Black and his Tenacious D bandmate Kyle Gass learn how music affects the brain.

Girls and boys. Guys and gals. Ladies and Gentlemen. No matter how you say it, it all comes down to the same thing: Male and Female. In this episode the male brain and the female brain go head to head. We’re going to pit teams of men and women against each other in a series of games and experiments designed to mess with your mind and show you how the genders are not created equally... from how we talk, to how we listen, and especially how we think.

Jason Silva travels to Israel to explore “The God Brain.” New research has uncovered that believing in God may be hardwired in our brains.

Whether it's full blown road rage or just the ever-present frustration at life's little inconveniences, we all feel a little mad sometimes. But what if getting angry had less to do with what's going on outside, and more to do with what's going on inside your brain? In this episode we'll explore why your brain gets angry and what you can do about it. Through a series of games and experiments, we'll prove to you that anger isn't always a bad thing, and how having a short fuse might not be the worst trait to have. Also you'll learn how to deal better with the anger of other people, and your own.

There's no better place than New York City to mess with your mind. Host Jason Silva leads viewers through a series of games and experiments designed to show that the brain has far more than just five senses, and how each of these work together to influence interactions with the world.

NFL football player Drew Brees puts his brain to the test with a series of mental challenges exploring how humans have hacked their brains; Keegan and Drew play a game called Draft Day, which shows how the brain must react quickly and be flexible.

Actress Rebel Wilson joins Keegan-Michael Key to explore the power of the subconscious when it comes to falling in love.

This is a show about your brain and trust. Does it sometimes seem like you have to be on your guard all the time against untrustworthy advertisers, politicians, and other people? So how do you maintain a level of trust in an untrustworthy world - and what is trust anyway? Through a series of fun and interactive games, you’ll learn to trust others a little more and your own brain a little less! Prepare to put your trust in Brain Games.

Whether you're trying to get to the head of the class, earn the big promotion, or just find a parking spot—every day, you're competing. With yourself... and with others. So what is it about the human brain that makes you want to win—sometimes at all costs? In this episode we'll explore your brain and competition through a series of competitions! Each viewer will be assigned a team and play along as our Red and Blue teams duke it out in a head to head battle to determine the winner of “The Brain Games.” Along the way you'll learn what drives you to compete, why some people may be born more competitive, and how a little healthy rivalry can help you climb the ladder of success.

This is a show about your brain and money. It's present in every corner of our lives-we earn it, spend it, manage it and often obsess over it, but how well do we really understand it? If you play along you'll understand why your brain gets excited when you think you're getting a deal, why there's no such thing as a free lunch, and you'll learn how to stop paying more for less.

Every time you make a decision, your brain enters an often invisible battle between risk and reward. Through a series of addictive interactive games, surprising experiments, and relatable experts you'll learn astonishing facts about how you make decisions - and how to get better at making them.

Whether it's remembering where you parked the car, or just finding the light switch in the morning, navigating your busy world can be tough. Luckily your brain has a built-in navigation system to help make sense of your surroundings. In fact, recent discoveries prove that the brain uses place cells and direction cells to help get us to where we're going. In this episode we explore spatial awareness. It's how your brain tells you where you are. Through a series of games and experiments we’ll test the boundaries of your brain’s hardwired sense of direction, and prove how you aren’t always aware of your surroundings or even your body. Plus you’ll learn a surprising technique to enhance your spatial memory.

Your mind and your body are connected in countless ways, some more mysterious than others. One might even call them "frenemies"—at times they work together like the best of friends, at others they fight like the fiercest of enemies. In this episode, we'll reveal what's happening when your brain betrays your body and the other way around. You'll learn some secrets about your body's reaction time as well as some physical feats that will baffle and amaze your friends.