The luckiest moment in a man's life gives way to a dark mystery when he vanishes after winning a multi-million-dollar lottery.

A small town is rocked when a popular hostess at the town's favorite tavern disappears; neighbors in the tight-knit community eye each other suspiciously, unaware that the answers may lie beneath the rolling Nebraska Sandhills.

When the popular owner of a boutique motel on an island paradise in Florida disappears amid signs of foul play, the deadly secrets of a quaint beach town slowly work their way up through the pristine white sand.

When a successful lawyer's body is found buried in a South Floridian canal, detectives use innovative technology to follow the gruesome steps taken by an evil killer.

An entrepreneur forges an unlikely friendship with a ragtag group of skateboarders; but when he vanishes and signs point to foul play, police wonder whether he was really a friend or a target.

A cowboy more at ease with horses than people vanishes into the desert after running into a group of California ranchers who believe he's done them wrong. Police must determine whether he rode off into the sunset or was the target of a deadly vengeance.

A California mom of three vanishes, and her car is found by the side of a desolate road with a suspicious flat tire. The case goes cold for years until a new detective takes on the case and is determined to get answers.

A night out on Hollywood's notorious Sunset Strip leads to a desperate search when a teenage girl doesn't make it home. The search for answers weaves though the strange side of Los Angeles before the tragic truth is uncovered in the Hollywood Hills.

When a high school student mysteriously vanishes, police must sort through the whispers, lies, and deeply personal secrets of a group of teenagers in a small Michigan town to unearth the deadly truth.

A missing young father in Utah returns home and confesses to an affair but vanishes again.

A Colorado woman vanishes shortly after moving in with a group of friends.

The discovery of a body buried in a Delaware backyard launches police into a twisted investigation.

A former judge retires to Florida and becomes the center of a mystery when he vanishes.

A weekend getaway becomes the center of a mystery when a respected college professor disappears.

A popular librarian vanishes after a night of dancing in Kentucky's capital city.

Police believe the discovery of a body in a backyard ends the desperate search for a missing woman.

A beloved Missouri couple is thought to be swept away in a record-breaking deadly storm, but when a closer look at the family farm points to foul play, law enforcement searches for clues long since washed away.

When a Michigan mother disappears on an afternoon walk, investigators pin all hope on their sole eyewitness: a 10-year-old boy who may have witnessed the unthinkable.

When a successful Arizona businesswoman disappears on a holiday shopping trip, investigators hunt for a kidnapper; when the killer takes his secrets to the grave, however, the only chance of finding her is a psychic's mysterious vision.

A young couple sets out from a holiday visit but never make it home as law enforcement search dangerous terrain fraught with derelict silver mines. In the black night and bitter cold, what happens when no one can hear you scream?

A spunky grandmother and former bail bondswoman is a no-show at work, leaving friends and family desperate for answers.

When a California mother wakes to find the door wide open and her daughter missing, law enforcement travel the country to find her until they discover a dark plot that began at the teen's doorstep.

When a widower disappears from his Southern California home, investigators find themselves caught up in a federal investigation involving the infamous hunt for skyjacker D.B. Cooper.

When a promising forensics student is found mutilated on a lonely stretch of Utah motorway, her Sheriff's department colleagues will stop at nothing to deliver justice.

Detectives attempt to trace a young woman's last steps as she leaves a casino and disappears into the night. An almost forgotten childhood memory helps find her buried in the backyard.