When Dean Loward finally closes a problem fraternity house, the university uses it for overflow housing, placing four freshmen under the supervision of the former fraternity president and his sometime girl friend.

Ophelia and Lisa go streaking across the campus and wind up stuck in the Dean's office where they hook up, but when Ophelia tells James about the encounter her informs her that the Dean has a security system taping all activities in his office. That sends the couple on a mission to recover the incriminating tape. Meanwhile, Jose and Freddy try to learn the secret of nerdy John Silverman's success with the ladies.

The co-eds are back but without womanizing party boy, James. Now that he is married to Ophelia he has gone to Florida to seek job opportunities. A series of sexual experiments wins Ophelia a research grant and the opportunity to travel to Florida with her research team, aka the co-ed housemates, in tow. Ophelia is excited about reuniting with her new husband, but can marriage really change the old James?

Students are caught up in a phony campus-wide scare when a video about a fictional serial killer is mistakenly released as real news causing everyone to believe a real killer is stalking unwitting coeds. Add a blackout to the mix and the result is mayhem of the erotic kind.

Dean Loward decides to let James graduate in order to be rid of him. Zach, Karen and Larry rent a dilapidated Frat House with incoming freshmen Victoria, Maxwell and Olga, and throw a farewell party for James. But will James really be able to leave college life and his merry band of friends?

Ophelia is having passionate flashbacks to her time with James, which disturbs her relationship with Ring. Larry turns to James for romantic advice. Karen is visited by a guy from her past (summer) and Emmanuelle amuses herself when not otherwise occupied.

When Jose naively attempts to help a young woman and is jailed his roommates plan a jailbreak.

The co-eds go wild as they try to out do each other in a Spring Break sex competition. Karen and Zack attempts to sabotage each other's sexual conquests may leave them both off the scoreboard. James' past secrets are revealed.

In the season finale, Ophelia receives the news that she won her grant and will be leaving for Borneo in a week. The end of the semester means that friends will be parting and the gang quickly plans a party where a number of surprising twists ensue.

Larry plans a Sci-Fi themed student film with the dual goals, a passing grade and the attention of the girl of his dreams. Cooper offers his unique vision to the project adding a pornographic slant to the production.

Karen's divorcing parents show up to the house. Emmanuelle finally tells Karen the truth about being a French Exchange Student. James goes in search of the lost engagement ring.

A wet t-shirt contest at Johnson's bar brings out the wild, side of the Co-eds. While the Co-ed men try to use seduction in order to score points for their bar, Double D's, the Co-ed women get serious about competing as they sponge down and bare all. A certain rock star from James' past is back in the picture.

The sale of "Vantastic" creates a rift between Zach and Karen, forcing them to seek guidance from a school counselor; James and Layla battle their feelings for one another; Ciara spends the day seeking the identity of her mysterious lesbian lover; the girls object to a male-oriented theme for the weekend's reunion bash at the bar and agree to a touch-football game to settle the issue.

The free spirited Karen has a past and when a man shows up she gives everyone, particularly Freddy, a major shock when she identifies him as her husband… who is being followed closely by la migra.

A sold out concert by pop star Minx excites Karen so she decides to enter the Omega House in a radio station scavenger hunt with the prize of free tickets. Sibling rivalry rears up as Larry claims the right to captain the team over Karen's objection. A search ensues for a DD bra and a picture of an authority figure in a compromising position. Both teams manage to obtain one of the items but will Larry and Karen set aside their family feud long enough to claim the prize?

Karen resorts to kissing a girl to push Brody to leave her. Dick Johnson wants Jenny back -- if not in his bed, then perhaps in his bar. James' brother, Jessie, is back in town and wants to see Layla.

On the morning after the party, Olga, Victoria and Maxwell wake to confront their actions of the night before. James discovers that his ex-wife, Layla, has enrolled as a student, while Larry gets paired up with his former girlfriend, Ciara, in film class. Dean Loward remains determined to get rid of James, and puts obstacles in the way of his success.

The bar is having financial problems, so Zack and Larry decide to raise money by making sexy co-ed party movies. James is upset because Ophelia is gone and becomes infuriated when Royce, Ophelia's cheating ex-boyfriend, shows up and makes the moves on his younger sister, Jenny.

In order to make money for the bar, James hires a hypnotist to perform. The co-ed gang each decides to use the hypnotist to jumpstart their sex lives. James wants to use hypnosis to reveal that Royce is being unfaithful to Jenny. But tapping into one's subconscious may not bring the results that they all hoped for.

Zack and Stacey put an artistic spin on their lovemaking. Royce and Dick Johnson battle for Jenny's affection. Karen is fearful that her relationship with Brody is over. James uses Blowjobs and Ball Sacs - his signature cocktails - to help keep Double D's from foreclosure.

It's a new school year and the gang's not all here. Dean Loward is determined to rid the campus of Omega House and his plan includes demolition. James attempts an intervention with the demo man by reviewing the events of the previous school year. One returnee is Karen who protests the destruction of he campus home. She returns along with her soon to be divorced father and stepmother. Daddy suggests that Karen and her friends live this year in his vacation home. Karen agrees and thus, Omega house moves to a luxury dwelling where James continues reliving memories of the previous year.

Rush week places the residents of Omega House in a variety of erotic positions.

Freddy's addiction to pornography causes his house mates to stage an intervention. He denies he has a problem but finally agrees to a challenge. If Freddy goes one week without any sexual gratification, they will leave him alone on the subject. Can Freddy do it even with Karen's sexy attempt at sabotage?

Larry is torn between his lust for his film muse Sophie and his affection for his film buddy Ciara while James and Ophelia begin to reconnect; Emmanuelle helps Karen and Cooper connect while she finds a new partner.

After Karen makes Lisa's sexual history public knowledge, she and the Omega House crew decide to help Lisa find her true love with an Omega House special, a wild Blind Date party.