Shock waves ripple throughout Clearwater, Florida, when an attractive waitress is found on her bedroom floor stabbed 16 times. As years pass and the case goes cold, police fear DNA might not even find justice for Laura Colannino.

Palo Alto's community sympathize with wealthy property developer Ken Fitzhugh when his wife of more than 30 years, Kristine, falls to her death down the basement stairs. But police are suspicious from the get go: there is just too much blood at the scene.

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Winston-Salem in 1982 is a city divided by race. And when a young white copy editor is raped and stabbed to death blocks from where she worked, the atmosphere is tense. Twenty years pass before Deborah Sykes' killer finally faces justice once and for all.

A McDonalds restaurant manager is murdered in a small Tennessee town and the police force goes into overdrive. But with a big list of suspects investigators are baffled and the case goes cold. Two years later, a tip brings them to Delma Ramsey's killers.

When Rachel Kosub is discovered naked, brutally raped, and strangled to death on her office floor, San Antonio police question who could commit such a vicious murder. They struggle to identify a killer until DNA analysis cracks the case, 20 years later.

A budding college football player's life is cut short when his 21st birthday party ends with his brutal murder. A gun shot to the head with a bullet wound so exact that Lexington police think it looks like a hit. But who would want to kill Trent Digiuro?

When Jim Webb, Co-Owner and Head Chef of the General Wayne Inn outside of Philadelphia, is found shot to death in his office, police hatch a plan so risky it could mean letting a killer run free forever.

When Wharton business student Shannon Schieber is found raped and strangled to death in her Philadelphia apartment, the city errupts with outrage as it's discovered that Shannon's death is the the latest in a string of rapes in the Centre City area.

A murderous attack in Park Slope, Brooklyn, leaves Sylvia Lugo dead and her girlfriend, Amanda Leach, raped and shot in the leg. Police struggle to pin down an assailant without any hard evidence, resulting in Leach being pegged as the prime suspect.