When the body of free-spirited Bonnie Ruphard, 47, is spotted by a runner in Lafayette, Louisiana, police suspect domestic violence; the case sits for a decade until DNA places a sprawling Bayou family under the microscope for her murder.

When Betty Jones and Kathryn Crigler are brutally attacked in a home invasion, the tiny community of Starkville, Mississippi, is left living in fear; decades pass and a detective devotes himself to cracking the case using new technology.

In 1991 Curtis "Cochise" Smith, 29, heads out for nappies in Plaquemine, Louisiana, and vanishes. Twenty-five years later, a body surfaces in the bayou and Cochise's murder case reignites. A local with a long rap sheet becomes the prime suspect.

When the supposed great-niece of Marilyn Monroe, Krystal Jean Baker, 13, is found dead beneath a bridge in Texas' Bayou Country, investigators are stumped. The quest to track down her killer will take investigators 14 years, and lead to a new law.

The town of Alexandria, Louisiana, is rocked when the body of Courtney Coco, 19, is found dumped 200 miles from home in Winnie, Texas; the case cools until a retired homicide detective turned podcaster discovers her killer hiding in plain sight.

When a young mother, Selonia Reed, 26, is found brutally murdered in her car, detectives turn over every rock in small town Hammond, Louisiana in search of her killer. Selonia's case languishes for more than 30 years before justice is finally served.