A cup of coffee in the 18th century takes James to the pioneering woman who discovered the structure of DNA, and a future with genetically engineered people. Will we want to be Super-Human?

James opens a cabinet of curiosities to discover how the French Revolution, wallpaper, and NORAD brought about the rise of big data – and a world where humans finally merge with the internet.

Dog pee, the Polaroid camera, and rocket fuel lead us to a future where AI is indistinguishable from human intelligence. If we can’t tell machines and people apart, what will that mean for humanity?

James connects the dots between Napoleon’s toothpick and the Nielsen TV ratings to see how scientists have built the quantum computer – a data-processing machine so powerful that it can predict the future.

James jumps in the sensory deprivation tank with a man who took LSD with dolphins to discover how syphilis in the French aristocracy kicked off a journey to the nanofabricator–a machine that can build anything you wish for, molecule by molecule, for free. What will that mean for the value of things?

How did a journey that began thousands of years ago with the Inca and the potato, connect to a mad scientist in a castle, and German beer, then bring us to the brink of a future with clean, limitless energy? And what will that future mean for humanity?