In their battle against the cartels, Customs and Border Protection flag a tractor-trailer transporting tanks of liquid methamphetamine; officers nab an exotic reptile smuggler; 36 pounds of cocaine are found inside a pickup truck.

Officers question a man traveling with two children that aren't his; a traveler is caught smuggling cash; drugs are found concealed in a flatbed truck; a drunken man is restrained in Progreso, Mexico.

Officers in Laredo, Texas, help a troubled 14-year-old; drugs sent through the mail are seized; a nurse in Progreso, Mexico, is caught smuggling fentanyl; a woman with children is stopped; a drunken woman bares all to officers.

At the Brownsville, Texas, point of entry, officers encounter drug trafficking, fraudulent documents and illegal merchandise; authorities seize $7 million worth of marijuana hidden inside a rolled carpet during a routine cargo inspection.

Meth is found inside the walls of a trailer; brothers are caught smuggling prescription medication; illicit Mexican delicacies are confiscated at the border.

Upon detaining a woman smuggling Tramadol and Xanax pills, officers discover she is part of a larger drug ring; officers arrest a daily crosser after finding cocaine in her vehicle; an officer's hunch leads to the discovery of 500 kilos of marijuana.

Officers discover methamphetamine hidden inside a truck's speakers and confiscate drugs packed deep within lead boxes; a woman denies trafficking pain pills; a man is interviewed to confirm his citizenship.

A man returning from Mexico requires emergency Narcan after a suspected opioid overdose; an unlikely family is caught trying to smuggle firearms into Mexico; a woman attempting to sneak prescription meds into the U.S. is caught red-handed.

A man who arrives at the border with a baby is concealing another valuable commodity; a couple who fails to declare Mexican avocados ends up causing a scene; a teenager claiming to be a U.S. citizen arrives looking to attend high school in Texas.

Following the work of America's Customs and Border Protection agency, whose job is to defend the border and stop terrorists, drugs and illegal weapons from entering the country.

The cartel tries to sneak one last shipment over the border just before midnight; officers uncover a delivery that isn't what it seems; a woman acting erratically is found with a Santa Muerte statue, indicating she may have cartel connections.

Methamphetamine is found hidden within a semi-truck full of frozen broccoli, a man is caught smuggling pills inside containers of protein powder, a traveler tries to bring a deer trophy across the border, and an intoxicated US citizen is detained.

A woman returning from a shopping trip in the US attempts to smuggle dirty money into Mexico; a van full of clothes is hiding an exotic shipment; a man finds a clever hiding place for prescription drugs; a family tries to bring in illicit fruits.

A drunk driver causes a three-car crash; a man attempts to import counterfeit goods; an investigation is launched into a pill-smuggling ring, and a shipment of cocaine is found inside office furniture; an armed robber on the run is captured.

Dirty cartel money is found hidden in a truck; an intoxicated minor requires medical treatment; a man tries to enter the US with a false visa, and two sisters are caught smuggling meds; a large quantity of cocaine is found hidden inside trash bags.

Officers stop a man suspected of money laundering. Cocaine is found hidden in an unexpected area of a shipping truck. A traveler is caught trying to bring weaponry into Mexico. A father is stopped when trying to smuggle medication for his son.

An illicit shipment is disguised in bags of concrete. Officers identify a criminal wanted for burglary when he attempts to cross the border. A woman is caught smuggling too many diet pills. A retired police officer almost carries a gun into Mexico.

Officers find a surprise in a car that hasn't crossed the border before.

Agriculture specialists deal with cattle arriving without required seals.

An elite team prepares for the extradition of a cartel Sicario, or hit man wanted for murder in his home country; with the sale of guns and ammo strictly controlled in Mexico, cartels turn to America for the weapons to wage their wars.

K9s save the day, identifying gallons of paint and beer bottles filled with more than the officers bargained for; a man with a warrant for his arrest is concealing something suspicious; officers question the intentions of a chatty traveler.

An officer catches a woman trying to use a forged visa to get into the US; a rookie officer takes part in a major cocaine seizure; officers suspect a traveller claiming to be a pastor on the way to a religious conference may not be who he says he is.

Officers see a trend of narcotics being smuggled inside car dashboards.

A new officer makes one of the biggest drug busts her bridge has ever seen.

A couple from Mexico arrives with candy unfit for children's consumption.