Hard-working family man Chris MacCallum disappears while on a camping trip deep in the forest along the border of California and Oregon. And when detectives start to unravel the mystery, all roads lead to an unthinkable suspect...

In Silicon Valley, young mother Reina Swierski is reported missing not by her husband Gary, but by her lover Ted. The search to find her goes on for years, eventually unmasking a violent and deadly predator.

When the murdered body of Miami pediatric nurse Beverly Jackson is discovered under the most shocking of circumstances, her family is devastated. In the end, it takes the bravery of one young witness to finally crack the case.

A troubled young mother mysteriously vanishes from her new home in Benson, Arizona where she had moved for a chance at a fresh start. Police uncover the truth of Devvra's disappearance when tips lead them through the seedy underbelly of Benson.

In the shadow of the nation's capital, a mysterious death on a Marine base confounds the NCIS -- was it an accident, or was it a homicide? It won't be long before police are hunting a violent sexual predator whose trail leads right back to the base.

In El Cajon, California - a haven for Iraqi refugees - a young mother is brutally attacked in her home and left fighting for her life. A note left at the crime scene lead police to believe it was a hate crime. Was Shaima's Iraqi community also in danger?

When beautiful fitness-fanatic Donna Zinetti is discovered brutally stabbed to death on a jogging path, detectives immediately suspect her recently-estranged husband, Keith Longtin. But not everything is as it appears.

A woman driving solo to visit a friend on Florida's I-95 mysteriously vanishes. Her divorce leads police one way, but when her body is found it suggests something horribly different. Another woman who reads about the case has a hunch she knows the killer.

The peace in a small town is shattered when a Muslim couple is gunned down on the street. Though badly injured, the husband survives and tells police the gunmen yelled racial slurs before firing. But was hate the only motivation for this heinous crime?

When 91-year-old Washington VIP Viola Drath is found dead on her bathroom floor in her tony Georgetown townhouse, it appears she's simply the victim of a nasty fall. But the subsequent investigation into her death unravels a lifetime of violent secrets.

Police discover a woman shot dead in a Catskills vacation house, just before it goes up in flames. The terrible conflagration masks even more terrible secrets, three deaths and a mystery that spans years - in this stranger-than-fiction tale.

A brazen assassination in a small Texas town sets the community on edge. With the killers on the loose, a team of special investigators tries to solve the case. They uncover a vicious revenge plot, but can they nail the killers before they become targets?

A terminally ill 87-year-old man is found dead from an apparent fall down his basement steps. But detectives soon realize the scene has been staged. Who stands to gain from the quick death of a dying man?

When the body of a murdered young woman is found floating in the Gulf of Mexico, detectives spend years trying to identify her remains. But then a family stumbles across her description, leading to a 30 year old murder mystery that demands justice.

When a 3-year-old child goes missing from a Cincinnati Park, the community mobilizes in a massive hunt. But before long, detectives realize that not all is as it seems to be and uncover a terrible secret.

When Chicago detectives launch a program to identify the remains of eight victims of an infamous serial killer, they find themselves unexpectedly solving a 35-year-old homicide.

A body is found engulfed in flames in a Los Angeles alley. He's thought to be the victim of brutal gang violence, but a tip soon leads police to the victim's ex. When new evidence is unearthed years later, it's clear the police were dead wrong.

Ruth Vosseler's estranged husband takes their two young sons on an overnight trip in 1986, but they never return. Ruth's frantic search for her fugitive ex-husband and two young boys spans 28 years and unearths dark family secrets.

When the nearly naked corpse of an older man is found along a horse path in Westchester, no one seems to know who he is. But after unraveling his identity, detectives are led on a four-state investigation -and learn his murder was based on a mistake.

Corey and Monique Kitts seem to be living the American dream with two children, a successful business, and a beautiful home. But when Monique and her children discover Corey's bullet-riddled body, the truth about their picture-perfect lives is revealed.

28-year-old Army veteran and beloved father of three, Joey Fulgham, is shot dead in his bed in May 2003. With so many suspects - Joey's wife, her jealous boyfriend, and even her protective teenage brother - police have a lot of ground to cover.

A strange case of a missing college co-ed pulls detectives into a disturbing online world. The investigation spans the globe and ends in Minnesota where an internet predator is unmasked.

When an Arkansas outdoorsman disappears, authorities wade through a series of accusations and rumors in their hunt for the missing man. As they zero in on a suspect and the body count rises, detectives rush to capture the killer before it's too late.

When a young woman vanishes from a New Mexico convenience store, two detectives discover tracks in the dirt that may lead them to answers. After a second woman disappears, it's a race against time to stop a potential serial killer.

A missing cheerleader. A seemingly unrelated roadside fire. As two cases converge, police juggle numerous suspects and motives, until a cryptic surveillance video brings the investigation to a shocking conclusion of betrayal, devotion, and murder.