Addicts, dealers and law enforcement officials speak about Baltimore's transformation into "the heroin capital of America."

As Memorial Day weekend approaches in Chicago, cops strive to get weapons off the street while drug dealers prepare for an influx of buyers.

South of the border, drug traffickers use every trick in the book to push mass amounts of marijuana into the United States.

On the rough streets of Oakland, law enforcement searches for a mysterious RB rumored to be driven by a high-profile drug distributor.