Eric and Erica have been kidnapped by their sister, Robin. They plan their escape from the bizarre school of brainwashed victims. Detective Ryan refuses to lie in a hospital bed while his partner’s murderer is on the loose.

Robin Cross has kidnapped Detective Ryan's daughter, Layla. Eric Cross joins in the search to find her. Tiffany Bradshaw is the new doctor at Mercy Hospital that is hell bent on destroying Erica Cross' life.

As Dr. Erica Cross plans for a wedding, she is shocked to find out her Ex-Love Doctor Cintron is now working in the ER. Detective Candice and Detective Ryan detain and question Erica’s twin brother Eric Cross about a murder that occurred across the street from his home. After coming to the Aid of her brother Eric, Erica faces the truth about her relationship with Doctor Bradley.

Eric helps his twin sister Erica out of a life-altering situation. While Eric searches, he and Erica commit the ultimate crime together. Dr. Cintron pursues Erica as he wants to mend their friendship. Meanwhile, Eric has an attraction for his new neighbor Gi.

After having made a pact to get rid of the local sex trafficking ring, Eric tortures Chauncy; a street thug, for answers about the missing girl Keisha Jarvis. Doctor Cintron admits his true feelings to Erica which she does not reciprocate. Detective Ryan sends Detective Candice home after she shows up to a murder scene intoxicated. While in the ER, Erica suspects a patient of sex-trafficking.

Lopez hones in on Erica concerning the disappearance of Dr.Lowes. Detective Ryan and Detective Candice suspect foul play in Kevin’s death. Eric gets one step closer to finding out who runs the sex trafficking ring. Nurse Brian manipulates to get Erica; the woman of his dreams.

Eric puts his hunch to the test and puts in a plan of action to rescue missing girl Keisha Jarvis. Dr.Cintron and Erica clash about their relationship. Detective Ryan and Detective Candice get a search warrant for Eric’s house.

The season finale explodes as Detective Candice and Detective Ryan finally attempt to arrest Erica. Detective Candice vows to attend rehab. Doctor Cintron and Erica can't help their feelings for each other despite the trials of their relationship. Eric tells Gi about his little Sister Robin. Eric and Erica have a stand-off with the Police.

After a tumultuous escape from Robin and Imani, Eric takes Erica to his lab to hide out from the Police. There, she discovers the depths of Eric’s vengeance on child traffickers. Robin and Imani have a power struggle over who’s in charge.

Erica reunites with Dr. Cintron who concocts a plan to retrieve the evidence that will get the murder charges against her dropped. Eric reunites with an ex-girlfriend to retain her services as an attorney to help Erica. Detective Ryan and his wife, Tanya, are having marital troubles.

Robin has to decide if she will go to war with Imani over her twin siblings. She comes face to face with Detective Ryan. Erica returns to her profession as a Doctor in the ER, only to put together the clues about Nurse Brian. Eric is in turmoil over how to rescue Robin from a life of crime.

Nurse Brian faces his ultimate fear of Eric’s wrath. Detective Ryan finds out Robin’s true identity after Officer Lopez regains her memory of the horrible night they were gunned down. Erica is forced to attempt the rescue of the children alone.

Imani is dead set on moving to a new location. Robin tries to stop her while making the ultimate choice between her siblings or a life of crime. Erica and Nurse Brian team up for a rescue operation. Eric sits in a cell in turmoil knowing Erica confronts danger alone.

Nurse Brian struggles with his mental state as his dark side emerges. DeAndre joins the hunt with Robin to right her wrongs in the search for Layla. Eric has an encounter with Keenya; a beautiful waitress that may have the missing pieces to the puzzle in his search for the missing girl.

Tiffany tries to convince Cintron to confess their past relationship to Erica. Meanwhile, Nurse Brian and Tiffany have immediate sparks between them. Erica keeps her radar up when it comes to her old college roommate.

Layla plans her escape from the kidnapper. Tanya and Officer Lopez team up to go after the clues that may bring them closer to finding Robin Cross. DeAndre comforts Robin as she faces her demons. Erica comes to help her sister Robin in her time of need.

Eric and Tiffany are becoming closer than either of them expected. Detective Ryan plans to infiltrate the auction in hopes of rescuing his daughter. Erica and Cintron struggle to hold onto their relationship.

Cintron and Erica’s relationship reaches its breaking point. Eric and Erica go undercover at the Mansion to find Layla while Robin has the same idea unbeknownst to anyone. Everything comes full circle as the siblings are willing to make the ultimate sacrifice for each other.

There is no time to spare for the Cross Siblings. Erica Cross has to figure out how to save her twin brother Eric and her sister Robin.

Dr. Tiffany and Nurse Brian cause turmoil in the Hospital among the staff; Erica finds an attorney to help her sister Robin.

Erica and Eric are blamed for Robin's escape from prison as the three siblings learn the identity of Gemini Cross; Nurse Brian's fears come to a head as a mysterious man named Cade enters town, terrorizing anyone in his path.

Eric searches for Keenya, having to go to Benny; Erica confronts Dr. Tiffany about the attempted murder on her twin brother; Gemini must stop Cade from destroying the siblings for disrupting his trafficking operations in the Heights.

Tanya gets her groove back with a younger man. Erica proves she is her brother's keeper and avenger.

Nothing can take the siblings down faster than the truth. They try to hold it together as the truth unravels in their pursuit to rescue Keenya.

Erica and Eric Cross are confronted with the ultimate nightmare, Eric's baby has been taken. The Cross family hits the pavement to find their baby. There is a new "Mother" who will do whatever it takes to win the favor of Cade Cross.