Damaso and Quino fight to take over the organization of El Chapo. El Chapo learns about the problems between Damaso and Quino and demands that they respect each other, but he knows that he must rush to escape from prison or they could ruin the organization.

After escaping the Puente Grande Penitentiary, Joaquín Guzmán Loera asks ‘Chito’ to turn himself in to the police and declare that only he helped him break out in a laundry cart. 'El Chapo' and 'Don Sol' agree to finish off the Avendaño Brothers.

El Chapo is taken to Mexico by the military forces. Conrado Sol has to make a press conference to present El Chapo as the most important drug trafficker of Mexico.

Joaquín Guzmán Loera promises 'Don Sol' he can end the failed Drug War and bring peace to the country. Thousands of innocents suffer the consequences of the conflict between 'La Federación', 'Los Emes' and 'Chente'.

Ramon will do anything to take revenge on El Chapo. Mr. Sol meets with Gabriela to question her about the murder of colonel Blanco.

Joaquín Guzmán Loera receives a visit from his second wife Graciela. After Amado’s death, Benjamín and Ramón Avendaño become the new drug-trafficking lords.

El Chapo gets upset to know that one of his women is with another man. After a long time in the punishment cell, El Chapo returns to his cell where he thinks he will rest from so many humiliations.

El Chapo asks his men to do social work on behalf of Esteban Prieto so that people vote for him. Esteban wins the elections and Don Sol is appointed Secretary of Governance.

El Chapo proposes Herrerias to give him part of his merchandise in El Salvador as long as he becomes his ally. El Chapo is summoned to talk about business with Herreria, but it is a trap of lieutenant Rosado to hand him to the police.

Arturo Bernal Leyda acts as peacemaker between Joaquín Guzmán Loera and 'El Cano' and 'Chente'. 'El Chapo' betrays the two fundamental partners of 'La Federación' to get one of his sons out of jail.

Joaquín Guzmán Loera heads to the funeral of his brother, 'El Pollo', murdered by 'Chente' and Raciel. 'El Cano' invades 'La Federacion's territory to kill 'El Chapo's men.

El Chapo is arrested by the army and Don Sol informs Esteban that the world will find out that they caught the most important drug trafficker in the world. Don Sol meets Franco and his wife discovers him.

El Chapo begins to get contacts in jail to avoid being extradited and escape. Esteban asks his wife to publicly clarify the problem he has with one of his properties and Don Sol is enraged when he realizes it.

El Chapo makes clear the distribution of his power if he could not take over the organization. Franco tells Don Sol that he will go to work in another state because he is tired of having to hide so nobody knows about their relationship.

Don Sol tells El Chapo that they must get a man to pose as him so that he can remain free. El Chapo asks an actress to make a film about him so that people always remember him.

Chino visits Ramon to give him information about the whereabouts of El Chapo in exchange of five million dollars. Ramon goes after El Chapo and turns the airport into a battle field.

Joaquín Guzmán Loera orders 'Don Sol' to avoid Andrés Labrador from becoming president of Mexico; he fears their business would be incompatible. Conrado schemes a fraud to make Felipe Alarcón the new Mexican ruler.

Joaquín Guzmán Loera is the leader of a drug war sponsored by Felipe Alarcón and 'Don Sol' against 'El Cano', 'Los Emes' and 'Chente'. 'El Chapo' bribes the jury of a beauty pageant in order to make Elba Coronado the queen.

Joaquín Guzmán Loera orders the hunt of Arturo Bernal Leyda, who attacks him in his territory of Sinaloa with the help of 'El Cano' and 'Chente'. Nazario Moreno walks out of 'La Federación' after 'El Chapo's new war.

Pain gets hold of Joaquín Guzmán Loera after the murder of his son, 'El Moreno', so he leaves Ismael in charge of the war. 'Don Sol' fears that 'El Cano', 'Chente' and Arturo Bernal Leyda might use 'El Chapo's weakness in their favor.

Gabriela is killed for having the copies of the files of El Chapo. El Chapo begins his days in jail and thinks about how to escape.

Joaquín Guzmán Loera escapes the GAFES’s arrest and later convinces them of working with him. 'El Chapo' organizes 'La Federación' with the ultimate leaders of drug trafficking after the Avendaños's fall.

El Chapo and his men find the perfect place to build the world's largest drug lab. Don Sol gives Franco money and demands that he stay away from him, but he rejects it. DEA analysis shows that the Sinaloa cartel has rapidly expanded operations in the entire world.

Isidoro leaves a message for El Chapo demanding him to defend his place, since he is determined to be his worst enemy. Elba tells El Chapo that she is expecting twins.

El Chapo and his men steal Isidoro's merchandise and destroy his laboratory. The army tries to catch El Chapo, but he manages to escape and Don Sol gets upset because he knows that it will be more complicated now to arrest him.