Tropical disease specialist Dr James Logan joins the team. Dawn and James travel to Thailand to look for embarrassing souvenirs Brits could be bringing home with them after a trip overseas. James infests himself with parasitic hookworm. In the United Kingdom, Pixie talks to Carol who has an addiction to coffee enemas. Christian attempts to help a woman who was one of the first to have breast enhancement surgery.

James continues his experiment of living with hookworm inside his intestine. Christian attempts to help a woman who had some botched cosmetic surgery in Thailand. Pixie talks to a patient whose huge breasts are ruining her life. Caroline's diabetes is damaging her sex life.

Christian is on the party island of Ibiza attempting to tackle the issues of too much sun, sea and sex. Back home, Dawn meets a man whose buried penis is causing problems going to the toilet. Pixie meets a young girl with an extreme case bad breath caused by swollen tonsils. James the dentist is back to treat different dental disasters.

This week Christian attempts to help a patient with a vasectomy. Dawn talks to a woman whose bowel condition has left her with really bad stomach scars. The seaside tour stops at Skegness, where the team attempt to help a man with a wriggly bottom and another man with a worrying lump on his testicles. Christian asks a team of BMX bikers to produce some sperm samples.

52 year old Patrick visits Dr Pixie about problems with anal leakage. Dr Pixie refers him to a consultant surgeon to find out what the cause is. The consultant discovers that Patrick has a limited diet which is very low in fibre, causing severe constipation. He is then referred to a dietician for advice on improving his situation by changing what he eats. Specifically the dietician recommends Patrick eats more fibre and drinks more fluids. On his return to the clinic he tells Dr Pixie there has been a big difference and he is able to do more than he used to.

The team are in Tamworth this week , where Pixie attempts to help a man whose bottom wound hasn't healed in six years. Christian talks to a woman with a mysterious whistle. Pixie pays a visit to a pop festival in Staffordshire, where microbiologist Professor Val conducts a forensic examination of the toilets. Dawn offers her top tips on nipples.

Ian sees Dr Pixie about some side effects he has suffered after slimming down. He weighed 27 stone and his rapid decline in weight has left him with a lot of excess skin on his chest and abdomen. The saggy situation is affecting his sex life because he has a large flap of skin and fat covering his penis. Dr Pixie refers him to a plastic surgeon because the skin has stretched too far to heal itself and will need to be removed. The surgeon removes skin and fat from his chest and abdominal area in a major operation lasting over three hours. During the operation about a stone in weight is removed from Ian’s body. Once healed he’s thrilled with the results and says he can now go running and swimming, activities that were previously physically impossible.

Caro visits Dr Christian at the clinic. For eight years Caro’s eyelid has been closed over. It started bleeding from the corner and has become progressively worse: lumpier, redder and it bleeds regularly. Dr Christian diagnoses it as arteriovenous malformation (AVM). This condition is essentially an overgrowth of blood vessels and can occur anywhere in the body. It’s very rare in the eyelid. Treatment is highly risky so close to the eye, so Dr Christian sends Caro to Mr Omar Durrani at the Birmingham Eye Hospital for more tests. Mr Durrani presents one option as being major surgery that would solve the problem but runs a 30% risk of damage to Caro’s eyesight. Caro goes for an angiogram from Dr Saleh Lamin. The procedure shows that her AVM can be treated without major risk to her eyesight, so Caro can now make a decision about what course of action to take, without the stakes being quite so high.

Nine months after they first met, the team catch up with the woman who had two large cysts on her head. Dr Dawn is in the Costa del Sol to see a man with a massive hernia. Dr Pixie revisits a woman who picked food out of the pits of her tonsils.

The team revisits memorable cases, including a man leaking milk. There's also transgender Jenny-Anne on her wedding day. And Dr Dawn and Dr Pixie show how to self check for breast cancer and which lumps to worry about and what to get checked out.

The doctors catch up with some of the show's most sensitive and scabby cases, all of them concerning the skin, from oozing, smelly underarms to a bottom wound that wouldn't heal. Dr Pixie catches up with a man who, having lost ten stone, went under the knife to deal with the problem of excess skin. Dr Dawn hits the beaches of Thailand to discover how a tropical skin complaint can turn into a holiday horror story. She also helps beach lovers keep watch on their moles. And Dr James Logan recruits Dr Dawn and Dr Christian to find out just what happens when 50 mosquitoes start munching on the skin.

The doctors catch up with some of the people who have come to the clinic looking for post-op help. For many ailments, surgery is the only answer. But sometimes surgery goes wrong. Dr Christian catches up with one of the first generation of women to have a boob job back in the 70s. Having followed the dramatic reconstruction of her breasts he returns to see the final 'cherry on the cake', with the making of her new nipples. Dr Pixie catches up with a man reeling from the results of surgery on his bottom. Dr Dawn meets woman who was left with terrible tummy scars. And Dr Christian advises some bold BMX bikers how best to keep your semen in tip-top health.

The doctors catch up with some of the most memorable problems involving the face. Dr Christian continues the story of a woman who opts for radical surgery hoping to see the end of her facial malformation. Dr Pixie catches up with mother of two who's on the mend after an extreme bout of teenage acne left her in despair. And Dr Dawn meets a woman whose face takes a bashing every time she goes to bed. Resident dentist Dr James is at the Stockton weekender flogging the benefits of flossing; and is on hand to help a woman who's badly stained smile has crumbled her confidence. And Dr Pixie has her nasal polyps checked out, a procedure not to be sniffed at.

n May and June of this year, nearly a hundred patients consulted Dr Christian Jessen and Dr Dawn Harper for medical advice over the internet. What Happened Next? catches up with a number of patients who took part who have already benefited from the advice or treatment they received. Among the many men and women featured, there's the student rugby player who memorably ripped an intimate piercing, and needed reconstructive surgery on his penis, and the woman who wanted help reducing the size of her particularly large breasts.

Dr Christian revisits two women who have gone to extreme measures to dramatically change their bodies. Their very different personal stories provide an insight into what it means to change sex. The programme follows the women's journeys and the lengths they've gone to in order to achieve their goal - from stories of love and bullying to butchery abroad and eye-watering surgery. Over a year later the programme catches up with them to see how life has changed since being in the clinic.