Fleeing fraternity boys who plan to gang-rape her, a figure skater is hit by a car and crippled. However, a mysterious old man sells her an antique wheelchair at a garage sale. The wheelchair is one of the cursed items, and allows the girl to use it to kill her victimizers and regain the use of a bit of her body with each death. Micki and Jack are out of town trying to recover an antique, so Johnny must deal with the matter on his own. He initially leaves the girl with the wheelchair out of pity, but she continues to kill. Ultimately, the girl is killed, and Johnny recovers the chair.

Johnny inadvertently screws up when he sells a box of junk to a retarded neighbor without checking the Manifest. A cursed antique car radio is among the items sold. The retarded man's brother, a car repairman and a racist, discovers that the radio can be used to travel back in time when smeared with a murdered victim's blood. He plans to travel back to the 50's in the South and prevent his father from being arrested and killed on murder charges, by killing the black lawyer his father tried to kill. Johnny and Jack, holding on to the car during the racist's second trip, travel back in time with him and manage to stop him. Ultimately, the racist ends up being burned at the stake by his father and other KKK members, who mistakenly think he is working with the black civil rights lawyer he was trying to kill.

20 years ago, a man's fiancee is stolen by vampires and transformed into one. Obsessed, he hunts vampires until the modern day, when he stumbles upon a cursed antique cross that lets him not only repel vampires, but incinerate them. Of course, he must kill someone to get the cross to work. Jack's friend, a priest, is the first one killed by the cross and Jack becomes involved as a result. Ultimiately we find out that the man's fiancee is now a willing vampire. Ultimately, everyone is killed, including the vampire hunter and his fiancee.

In the first few minutes, Micki and Johnny recover a yin-yang amulet that lets the user switch bodies after killing someone. They steal it from a wife and her lover trying to kill her husband, and manage to escape. But, on the way back they run out of gas and stumble on a home lived in by two brothers. The brothers are psychopaths who have stuffed their family to keep around the house, and they want Micki. Johnny breaks his leg, but uses the amulet to switch places with the younger brother. He eventually convinces Micki of who he is, and they eventually manage to restore Johnny to his original body. The younger brother is killed, and the other dying brother uses the amulet to inhabit the stuffed body of one of his family members. However, Micki and Johnny manage to puncture enough holes in the animated body that all the stuffing is blown out by the high winds of a storm.

Micki is sent through a two-way time portal contained within a painting and finds herself at the mercy of the Marquis de Sade.

Adam Cole and his partner run a vaudeville-style mental act using secret passwords. However, the act threatens to fall apart since Cole is losing his hearing. While being treated by a doctor, he finds an antique hearing aid in the doctor's collection. Using it, he discoveres that he can read minds, but the mental messages ultimately build up and kill the user...unless he discharges them into a victim. Either way, the result is a messy death. The trio track down Cole performing his new act. Left with nowhere to run, Cole can't ""discharge"" the accumulated thoughts and dies a gory death.

Desmond Williams, a director, is obsessed with the role that his now-aged actress-wife played 50 years ago: that of femme fatale Lili Lita in a film-noir crime film. He finds a cursed reel that lets him bring the Lili character to life, by pushing an innocent female victim into the film itself while its playing. The victim is forced to relive the entire movie...which ends with the character they are stuck as being killed. Meanwhile, the movie version of Lili emerges into the real-world for the same period of time. To stay alive, Lili must convince Desmond to kill her aged real-life counterpart. The character is also increasingly dissatisfied with her limited ""life"" as a sex toy for Desmond. Ultimately, the aged actress shoots her husband when she finds out what is going on, and decides to enter into the film (replacing a trapped Micki) so she can have her youth back. Trapped with nowhere to go when the film ends, the film Lili is destroyed for good.

A lonely, somewhat twisted mortician stumbles upon the cursed properties of an antique embalmers' aspirator. He can use it to kill one person, to resurrect another without memory. He kills someone with it and then uses it to resurrect a young woman he has fallen in love with. Unfortunately, the woman's husband begins to suspect, and the resurrected woman starts to remember her past life. Ultimately the mortician is killed after he starts a fire, and the women decide to remain in the fire and die again, leaving the trio to recover the indestructible antique from the ashes.

In the opening segment (to be repeated throughout the first two years), we see Lewis Vendredi try to recover the cursed antiques, and end up condemned to hell. Distant cousins Ryan Dallion and Micki Foster find out they have inherited an antique shop from Uncle Lewis. Micki wants to simply sell off the place, and Ryan reluctantly agrees. They sell off the antiques in the store, but then are greeted by Jack Marshak, Vendredi's partner and procurer. They find out about Vendredi's deal with the devil, and realize that some of the antiques they sold were also cursed. The first antique they recover, a toy doll, comes to life and kills for its owner, a young girl. They recover the doll, and vow to recover the other antiques as well.

A magician creates a new death-defying act using a pair of cursed antique ""magic boxes"" created by the famous magician Houdin. Anyone placed in one box can survive any danger...because someone placed in the second, hidden box suffers all the harm. Jack, a magician himself, enters a magic competition as the trio try to ferret out who is using the magic boxes.

A gardener's assistant gets hold of a cursed mulcher. The more wealthy and valuable the person you feed into it, the more money that comes out. The trio manage to feed the assistant into the mulcher, and nothing comes out. Meanwhile, Micki's fiancee Lloyd tries to convince her to give up the antique business, but at the end she declines, feeling obliged to continue recovering the cursed antiques.

A old and embittered comic book writer, Jay Star, gets hold of a cursed comic book that allows him to transform into Ferrus the Invincible and take vengeance on the individuals who stripped him of his legal rights to the superhero character he created.

A small farming community has excellent harvesters. Little do they realize that one of the farmers uses a cursed scarecrow. She must pin the pictures of three victims on the scarecrow's chest. When it claims all three victims, tracking them down and beheading them, the result is a good harvest. Micki and Ryan come looking for the scarecrow, but the scarecrow's owner soon realizes what they are up to and tries to use Micki's driver's license to make her the scarecrow's third victim.

Jack is asked by a friend to investigate a ""faith healer"" who uses a cursed glove to heal one person...by transferring their ills magnified tenfold to another victim. Jack must not only recover the glove, but deal with his friend, who is dying of cancer and needs the glove to cure himself.

A cursed broach possesses several strange abilities, including the ability to transform its wearer into a vampire and the ability to, when daubed with blood, let its wearer travel through time. Micki and Ryan find that the broach's owner, a female vampire, is trying to transform her new male tenant into a vampire. They manage to kill the female, but the transformed tenant, Frank, uses the broach to travel back into time to London in the late 19th century. Micki and Ryan managed to follow him. Befriended by a destitute writer, Abraham, and his fiancee, they manage to track down the vampire and kill him, but not before Abraham's fiancee is killed. They return to their own time, and Jack can only speculate that ""Abraham"" may have been Bram Stoker.

A homely girl, overshadowed by her prom queen sister, gets hold of a vanity which she can use to bedazzle any boy into falling in love with her. However, as soon as they do, she must then kill them. She eventually takes over her sister's boyfriend and has him hang her up by a noose. Micki and Ryan manage to save the girl, but the younger sister eventually commits suicide along with the boyfriend. The vanity is lost (although it will resurface in the second season episode ""Face of Evil"").

A young man, Tommy Chow, gets hold of a set of tattoo needles. He tattoes an innocent victim, and the tattoo then comes to gory life and kills the victim. In return, Tommy, a compulsive gambler, gets good luck in the games. The trio team up with Tommy's grandfather, Lom, a Chinese medicine man, and try to save Tommy's sister, the next victim, before the snake tattoo kills her. Unfortunately, Tommy is playing a game of high-stakes Russian Roulette when they save his sister.

An innocent man is condemned to the electric chair, but manages to survive. Embittered, the man buys the electric chair from Lewis Vendredi. A dentist, he takes a job in an orphanage and disguise it as a dentist's chair. He then kills the orphans and covers up their disappearance by claiming they are runaways. The killings let him electrically charge himself into a living dynamo, so that he can go out and kill those responsible for finding him guilty at his trial. The trio must ground him before he can kill again.

Jack and Micki, depressed because Ryan stayed with the Pennitites, learn that the Quilt of Hathor they have is a forgery when they are able to harm it (all of the cursed antiques are indestructible). They return to the religious community to discover that Reverend Josiah, Ryan's father-in-law to be, is using it to destroy his enemies in their dreams. Josiah, unhappy with an outsider romancing his daughter, has framed Ryan for the deaths. Ryan must fight in an old Testament-style trial by combat while the others recover the Quilt.

Winston Knight, a TV anchorman, gains great fame because a serial killer, the Machete Killer, will only contact him. What no one knows is that Knight is using a cursed camera that lets him create an exact duplicate of himself that goes out and kills for him, providing him with an ironclad alibi and great ratings. As long as he destroys the negative within the allotted time, Knight is fine. Unfortunately, Ryan's new girlfriend Cathy witnesses one of the murders and realizes Knight is somehow the Machete Killer. One of Knight's photo-duplicates kills her, but the trio are close on Knight's trail. Knight eventually fails to destroy one of his indestructible duplicates in time, and disintegrates. However, the duplicate has little time to savor its new life before it dies of previously inflicted wounds.

Tracking a cursed foghorn, Micki and Ryan arrive at an isolated community. Initially unbeknownst to them, the local lighthouse keeper is using the foghorn to summon up the ghost of pirate Angus MacBride, who kills his descendents in return for revealing more and more of his hidden treasure to the keeper. Ultimately the keeper discovers that he is the last descendent of MacBridge, and the pirate captain completes his crew at last.

Ryan's father Ray, a small-time inventor, rolls into town and announces that he's achieved great financial success and is planning to finally marry. Ray's managed to do so with the aid of a pipe given to him by Lewis Vendredi, which allows him to totally disintegrate first the young inventor whose ideas he stole, and then his rivals in the company he's working for. Eventually Ryan and Micki discover the truth. When Ray tries to kill Micki with the pipe, Ryan throws himself in the way. Ultimiately reconciled with his son, Ray then takes the blast of smoke for himself, dying to save his son.

Two desperate parents were given an antique cradle by a symathetic Lewis Vendredi. The cradle belonged to a female passenger aboard the Titanic. Trying to rescue her child, she accidentally capsized a lifeboat that killed seven passengers, but her child floated to safety. Now, the curse of the cradle lets the parents cure their ailing baby if they kill seven people by water while the baby is in the cradle. However, they must do so before the anniversary of the Titanic's sinking. Ultimiately, trying to kill the child's babysitter, the parents themselves both manage to die by water, inadvertently giving their lives to save their child. The babysitter ends up with the cured baby, and the trio recover the cradle.

Lewis Vendredi was defeated in the previous episode Bottle of Dreams, but he has another plan. Vendredi is using a mirror that he prepared before his death, hidden away in an old home that the cousins were unaware their uncle owned. The mirror will open a doorway to hell, and let Lewis escape. Vendredi possesses the body of one of two escaped convicts who has fled to hell. Jack must enter the doorway and destroy it from within, which he manages to do.

During a local voodoo celebration, Jack meets an old friend, Hedley, who is a voodoo houngan, and the ""Keeper of Fire"". Hedley's granddaughter Stacey is to be initiated as a priestess. However, the other three priests of the other elements are being killed off by Cole, a rich young man using a cursed voodoo mask. He is working for Laotia, a priestess who has promised him power but plans to take it all for herself once Cole has killed the priests. We eventually find out that Laotia and Hedley were married, and that Hedley had killed his wife years ago when she turned to evil. The cousins, Jack, and Hedley must defeat Laotia once and for all.