A homely record-store clerk is obsessed with pop diva Angelica, and happens to stumble upon a jewelry robbery where the thieves drop one of the items: a cursed pendant that first belonged to Dr. Mesmer. The curse lets the clerk fulfill his every wish by mesmerizing a victim into doing whatever he wants them to. He wishes first for attractiveness, and then for the diva's love and the chance to be close to her. Ultimately, however, none of this is good enough for him, and his final wish is to _be_ Angelica. The wish is successful, but Micki and Ryan, close on his trail, manage to intercept him/her at a concert and grab the necklace, undoing all the benefits it bestowed.

A woman and her boyfriend get hold of a cursed pocketwatch that lets the owner stop time for one hour (13 o'clock) if they kill a victim at a particular train station. Two street orphans witness one of the killings, and meet up with Ryan and Micki. By holding on to the couple, Ryan manages to enter their ""frozen hour"" and manages to get the watch away from them, leaving them trapped in time for eternity.

A Satanic cult leader gets ahold of the cursed Coin of Ziocles, and needs it to resurrect three powerful witches. Flip the coin and it comes up heads...killing the victim and allowing the user to resurrect someone else. Unfortunately, while spying on the cult Micki is captured and killed by the coin! Jack and Ryan are deeply hurt, and Ryan plans to quit antique-hunting once they've defeated the cult. Fortunately, they are able to substitute Micki's body for that of the third, mummified corpse, and the cult leader, Sylvan, inadvertently resurrects her instead. As the temple begins to crumble, Ryan grabs the coin and tosses it at Sylvan to deter him...but it's a fake. Unfortunately, Ryan loses the real Coin as well, leaving it buried under tons of rubble.

Two children trapped in an abusive home stumble upon a cursed playhouse. The playhouse lets them enter a fantastical world of clown and parties in return for them luring in a child. The trail of missing runaways attact our trio's attention. Micki and Ryan have to enter the house where they confront its sinister presence. They manage to convince the two children to reject the house, which frees the other trapped children. The missing children are returned to their homes and the two siblings are put into a foster home.

A mysterious snowglobe is mailed to Curious Goods. When Micki gives it a shake, an old boyfriend of hers shows up, and convinces her to join him at a bed & breakfast. Then Jack and Ryan are both visited by old friends when they shake the globe. It turns out that each of the three newcomers is working for Satan. If Micki can be tricked into sleeping with her boyfriend, then she will be considered wedded to Satan as she ""willingly"" did so. Jack and Ryan, lured to the hotel, are separated from her, able to witness what is going on but unable to contact Micki. It turns out they are trapped in the hotel within the snow globe. Ultimately, Ryan's ex-girlfriend helps them, and they manage to drive a car into the edge of the globe, knocking it off the shelf it is resting and shattering it (and freeing themselves) before Micki can consummate her wedding with the Devil.

In an insane asylum, a doctor is using a cursed antique radio to enact miraculous cures on his patients. The cost, as usual, is that the radio then kills another doctor's patients, by bringing their greatest fears to life. Tracking down the radio, Micki and Ryan must break into the asylum and recover the antique.

The trio become involved in a movie production when they loan some (non-cursed) antiques out to a set. Handsome actor William Pratt is the star, and Micki and he soon fall in love. Unfortunately, Pratt has two secrets: he is actually a disfigured ""monster"" actor named Jeff Amory, and he owns an antique: a cursed make-up case that belonged to John Wilkes Booth. Using the case, Amory can temporarily hide his disfigurement by mixing a victim's blood in with the make-up. Unable to bring himself to kill Micki whom he truly loves, he reverts to his normal features but Micki loves him anyway. He is locked up and the make-up case returned to the Vault.

An outcast college film student is obsessed with werewolves. Mercilessly teased by frat boys and rejected by the girls, he stumbles upon a cursed movie camera. When he films someone with it, he sees them being killed by a werewolf through the viewfinder. The victim is then actually killed by a mystically summoned werewolf. According to the camera, when the student kills three victims, he will get his fondest wishes. He does so, and becomes a werewolf himself. Ultimaitely, he tracks the trio back to Curious Goods, where they kill him by strangling him with the camera's film...made out of silver nitrate.

An eccentric wax sculptor and his wife tour with a carnival. Not so coincidentally, a series of ax murders follow the carnival and the ""Hall of Horrors"" wax museum the sculptor runs. Ryan falls for the wife, only to eventually learn that she had actually rejected the sculptor...who killed her and turned her into a wax statue. Now he uses a cursed handkerchief to reanimate her and force her to love him. However, she must be sent out to kill to maintain the curse. Ultimately, the wife, realizing what she has become, kills herself and her ""husband"" in a flaming tent.

An antiques collector, Atticus Rook, makes a fortune selling new antiques from the Civil War era. It turns out that they are "as-new": by fueling a cursed "magic lantern" with the blood of a victim, he can travel back in time through a slide of wherever he wants to go, until the lantern "fuel" burns out in three hours. Ryan and Micki follow, but Ryan is captured as a spy trying to get close to Lee (whose sword Rook is trying to grab). A local woman, Abigail, helps Ryan only to be killed by Atticus. Ultimately Micki helps Ryan to escape, and they go back to the present and blow out the lamp... just as Rook emerges behind them, dying a particularly gruesome death caught partway in a wall where the image was projected.

A doctor is trying to develop a cure for a childhood syndrome lending towards hyperviolence. Due to his mistake, his daughter was inadvertently infected with the disease from a contaminated needle. Now, the doctor uses a cursed silver syringe to suck out the essence of a small gland that controls violent behavior from unwilling prostitutes, and inject it into his daughter to give her a temporary cure. Unfortunately, the process renders the donor hyperviolent as well. A friend of Micki's is grabbed by the doctor and submitted to the treatment. Trying to locate her friend, Micki herself is kidnapped and subjected to the process.

While Micki and Ryan are on vacation, Jack has nightmares of his World War II experience when he was captured by the Nazis and nearly killed by Rausch, a commandant known as The Butcher. The Butcher used a garrotte made of barbed wire to kill his victims. Jack was saved by the rest of his battalion then, but now in the modern day his surviving friends are being killed off one by one with a barbed-wire garrotte. It turns out that an escaped Nazi, Mueller, is using a mystic talisman, the Amulet of Thule, to resurrect Rausch. Rausch, masquerading as a right-wing radio talk-show host named Walden, is seeking revenge on Jack and the others. Although the Amulet is not an antique, Jack must recover it to defeat Rausch and send him back to the grave.

A demented bee keeper, McCabe, uses a cursed antique beehive in a complicated scheme. First he turns loose the bees in the beehive, which kill someone and make a blood-honey. Then McCabe sells the honey to dying businessmen in return for lots of money. The businessmen must then kill their ""replacement"", and they take over their victims' bodies, abandoning their old lives. However, they have to keep eating the blood-honey (and paying McCabe more money) to maintain the bodies' health, or they revert back to their original dying infirmity. The trio get wind of the scheme, and kill McCabe with the help of one of the businessmen who finds that his new life isn't worth the loss of his loving, abandoned wife.

A crook names Railsback gets hold of a World War II kamikazi jacket. When smeared with the blood of a murderered victim, it lets the wearer become invisible. Railsback is in prison, but uses the jacket to escape and try to recover the stolen loot. He has to kill his former gang members to get it, a task made easier by the jacket. Railsback ends up killing Johnny Ventura's father, a security guard at a storage depot where some of the money is hid. Johnny is arrested for the crime, and put into the same prison as Railsback. He finds out about the jacket and tries to recover it, while Micki, Ryan and Jack try to clear his name from the outside. Ultimiately, Johnny manages to douse the invisible Railsback with gasoline and set him on fire, killing him and leaving the indestructible antique intact to be put into the Vault. Johnny is cleared of the charges.

In the opening segment (to be repeated throughout the first two years), we see Lewis Vendredi try to recover the cursed antiques, and end up condemned to hell. Distant cousins Ryan Dallion and Micki Foster find out they have inherited an antique shop from Uncle Lewis. Micki wants to simply sell off the place, and Ryan reluctantly agrees. They sell off the antiques in the store, but then are greeted by Jack Marshak, Vendredi's partner and procurer. They find out about Vendredi's deal with the devil, and realize that some of the antiques they sold were also cursed. The first antique they recover, a toy doll, comes to life and kills for its owner, a young girl. They recover the doll, and vow to recover the other antiques as well.

A magician creates a new death-defying act using a pair of cursed antique ""magic boxes"" created by the famous magician Houdin. Anyone placed in one box can survive any danger...because someone placed in the second, hidden box suffers all the harm. Jack, a magician himself, enters a magic competition as the trio try to ferret out who is using the magic boxes.

A gardener's assistant gets hold of a cursed mulcher. The more wealthy and valuable the person you feed into it, the more money that comes out. The trio manage to feed the assistant into the mulcher, and nothing comes out. Meanwhile, Micki's fiancee Lloyd tries to convince her to give up the antique business, but at the end she declines, feeling obliged to continue recovering the cursed antiques.

A old and embittered comic book writer, Jay Star, gets hold of a cursed comic book that allows him to transform into Ferrus the Invincible and take vengeance on the individuals who stripped him of his legal rights to the superhero character he created.

A small farming community has excellent harvesters. Little do they realize that one of the farmers uses a cursed scarecrow. She must pin the pictures of three victims on the scarecrow's chest. When it claims all three victims, tracking them down and beheading them, the result is a good harvest. Micki and Ryan come looking for the scarecrow, but the scarecrow's owner soon realizes what they are up to and tries to use Micki's driver's license to make her the scarecrow's third victim.

Jack is asked by a friend to investigate a ""faith healer"" who uses a cursed glove to heal one person...by transferring their ills magnified tenfold to another victim. Jack must not only recover the glove, but deal with his friend, who is dying of cancer and needs the glove to cure himself.

A cursed broach possesses several strange abilities, including the ability to transform its wearer into a vampire and the ability to, when daubed with blood, let its wearer travel through time. Micki and Ryan find that the broach's owner, a female vampire, is trying to transform her new male tenant into a vampire. They manage to kill the female, but the transformed tenant, Frank, uses the broach to travel back into time to London in the late 19th century. Micki and Ryan managed to follow him. Befriended by a destitute writer, Abraham, and his fiancee, they manage to track down the vampire and kill him, but not before Abraham's fiancee is killed. They return to their own time, and Jack can only speculate that ""Abraham"" may have been Bram Stoker.

A homely girl, overshadowed by her prom queen sister, gets hold of a vanity which she can use to bedazzle any boy into falling in love with her. However, as soon as they do, she must then kill them. She eventually takes over her sister's boyfriend and has him hang her up by a noose. Micki and Ryan manage to save the girl, but the younger sister eventually commits suicide along with the boyfriend. The vanity is lost (although it will resurface in the second season episode ""Face of Evil"").

A young man, Tommy Chow, gets hold of a set of tattoo needles. He tattoes an innocent victim, and the tattoo then comes to gory life and kills the victim. In return, Tommy, a compulsive gambler, gets good luck in the games. The trio team up with Tommy's grandfather, Lom, a Chinese medicine man, and try to save Tommy's sister, the next victim, before the snake tattoo kills her. Unfortunately, Tommy is playing a game of high-stakes Russian Roulette when they save his sister.

An innocent man is condemned to the electric chair, but manages to survive. Embittered, the man buys the electric chair from Lewis Vendredi. A dentist, he takes a job in an orphanage and disguise it as a dentist's chair. He then kills the orphans and covers up their disappearance by claiming they are runaways. The killings let him electrically charge himself into a living dynamo, so that he can go out and kill those responsible for finding him guilty at his trial. The trio must ground him before he can kill again.

Jack and Micki, depressed because Ryan stayed with the Pennitites, learn that the Quilt of Hathor they have is a forgery when they are able to harm it (all of the cursed antiques are indestructible). They return to the religious community to discover that Reverend Josiah, Ryan's father-in-law to be, is using it to destroy his enemies in their dreams. Josiah, unhappy with an outsider romancing his daughter, has framed Ryan for the deaths. Ryan must fight in an old Testament-style trial by combat while the others recover the Quilt.