The Eiffel Tower beomes the latest monument to vanish into the ground as Dr. Claw begins collecting the world's monuments. Gadget and the Gadgetinis investigate the tunnels leading from the tower and capture a teenage mutant ninja gopher (I'm kidding about the ninja part). Gadget figures the case is solved but Penny realises the gopher is young and that its even bigger mother will come looking for it.

Cold temperatures strike beach resorts around the world while Antarctica becomes a tropical paradise. Gadget is assigned to go to Hawaii to investigate but suddenly decided to go to the South Pole instead after seeing an infomercial by Cindi, the head of the new "Down Under Estates" condominum development. Penny investigates and finds subliminal messages in the ads which are luring in buyers and realises her uncle's heading straight into a MAD stronghold.

After suffering a serious attack of stress-induced pimples, Colonel Nozzaire decides to take his therapist's advice and keep Gadget as far away as possible with work missions. So, he sends Gadget to Hong Kong (the first place he thinks of) to buy office supplies for WOMP. Meanwhile, in Hong Kong, control of the Banan business empire has just passed to Amanda Banan as a graduation present from her father. Amanda's being targeted by Dr. Claw who wants control of the corporation and thinks she'll be easier to crack than her father. MAD agents are sent in to infilitrate the headquarters of Banan Communications and take over the top two floors, which is how Amanda finds herself on the roof tied to a satellite dish with the choice of signing control of the company over to MAD or being roasted by a high power transmission that's due at noon. Thanks to one of his usual mixups, Gadget is wandering through the building convinced it's a stationary supplies warehouse.

WOMP unveils Super Gadget Girl (but since that's a bit long everyone calls her Super GG or just GG), a state of the art fembot who is tougher and smarter than Gadget. But unlike him she's entirely machine with programmed emotions and programming can be changed, which Dr. Claw intends to do so she'll steal the world's gold reserves for him and eliminate Gadget once and for all.

Albert Alkaline (aka AA), the world's major battery manufacturer, is worried that MAD intends to kidnap and ransom his extreme sports fanatic son Alan Albert Alkaline (aka AAA). Since he's offering a large reward and WOMP is low on funds again Genral Sir agrees to protect AAA. After hearing that all the other bodyguards AAA had got mangled trying to keep up with him during his extreme sports events, Colonel Nozzaire is happy to assign Gadget to the case.

The 10 biggest banks in New York have been robbed but despite the break-ins happening in broad daylight there are no eye witnesses, the security cameras shut down and no one can remember what happened. The only clue is that everyone who was in the banks remembers hearing bagpipe music before the robbery. The police have no clue so WOMP is called in and Gadget is sent to Scotland accompanied by Penny & the Gadgetinis to investigate the only clue - a security camera closeup of the name McIntosh's Magic Bagpipes Inc. on the pipers bagpipes.

Gadget & Colonel Nozzaire are sent to the Colonel's old desert Foreign Legion post to investigate rumors of female criminals converging on the area. What they don't know is that Dr. Claw's archeologist, Professor Suzuki, is looking for a lost temple holding an ultimate weapon that requires 12 women to unseal it.

The tiny Himalayian country of Goldmanchu's only export is the gold created by the midas touch of the simpleminded mystic Golda (whose right hand turns things to gold and left hand turns things to wood). Golda's existence was a closely guarded secret but WOMP fears Dr Claw has learned of him and intends to use his golden touch to destabilize the world's economy so Gadget is sent to Goldmanchu. Unfortunately, Golda has already been replaced by an imposter with orders to eliminate Gadget.

With General Sir in the hospital and Colonel Nozzaire finally getting a field assignment trying to track down Dr. Claw, there's no alternative but to make Gadget the acting head of WOMP. While Gadget uses General Sir's secretary Miss Miffet as a model for his ideas for new WOMP uniforms, Colonel Nozzaire is captured and brainwashed to recommend that the Board of Megapowers shut down WOMP. Can Penny and Chief Quimby work together to get Gadget to save WOMP?

Dr. Claw has a MAD scientist build a time machine then travel back to 1957 to prevent Gadget's parents Jules and Annie from meeting. Back in the 21st century, Gadget begins to fade away and so does Penny and the Gadgetinis since she can't exist without her grandparents and if she's never born there's no one to build them. While the scientist delays Jules, he still manages to crash his bicycle into Annie's and everyone reappears. The Gadgetinis and Gadget travel back in time to find the scientist who gets Gadget locked up but Gadget breaks out of the police station accompanied by his cellmate Marilyn, who was destined to meet Gordon Claw in the holding cell and eventually become Dr. Claw's mother. So, now the scientist has to try and get them together while breaking up Jules and Annie's budding romance and the Gadgetinis have to stop him.

General Sir thinks MAD might kidnap global rock and roll superstars "The Mummies Boys", so Gadget is sent to protect them. Since the Boys are Penny's favorite band, she tags along, unaware that Dr. Claw has bigger plans. Backstage at the stadium for their soon-to-air global concert, Penny overhears their new Soundman talking to Dr. Claw about putting a mind control signal into the broadcast which will be watched by about 2 billion people. He spots Penny and leaves her tied up in a trunk. Meanwhile, the opening act "Pharoah's Men" is booed offstage so they load up their bus and leave taking Penny in the trunk with them. Turns out Penny's wristwatch still has the laser from the original series so she cuts herself free then persuades the band to go back and save the crowd who rejected them. Meanwhile, the Soundman arranges to eliminate Gadget with the show's special effects during the concert and as always Gadget is oblivious to the danger.

A microscopic implant has been detected in the brain of General Gastritas. It's suspected to be a MAD mind control device and since he's about to be made Supreme Commander of the Mega Powers militaries, WOMP can't afford to take chances. So a volunteer is needed to be miniaturized by an experimental process and injected into the General's Brain to remove the device. It's a one in a millon chance of surviving the mission so Colonel Nozzaire is happy to volunteer Gadget. Gadget, the Gadgetinis and the Gadgetmobile are shrunk and injected into the General's skull to face angry white blood cells who don't like intruders and miniaturized MAD agents ready to defend the mind controller. Just to complicate things further, the scientists made a miscalculation when they shrank them and they have only a few hours rather than days before they return to normal size.

Dr. Claw's mother (the one person in the world he fears) orders him to take care of his nephew Billy while he's on summer vacation from his boarding school. She also tells him that Billy is unaware of their family's criminal history and that's the way she wants it to stay. Far as Billy knows, he's being sent to stay with his Uncle Gordon, a wildlife biologist studying the animals on a tropical island. So that's what he tells Penny when he meets her at the airport when she arrives on the same island for a camping vacation with her uncle. Gadget's arrival infuriates Dr. Claw and gives him the problem of how to eliminate his enemy while keeping his nephew from knowing he was involved in Gadget's demise. Fortunately, his experiments on controlling the wild animals of the island offer a solution.

Dr Claw is stealing vintage aircraft either for his personal collection or to build up a private airforce. Either way, Gadget has to find him and save the day, which, thanks to Penny and the Gadgetinis, he once again manages to do.

Gadget is successfully abducted by MAD Scientist Dr. Von Headcase who intends to brainwash him. Penny spends a week trying to locate him. Having exhausted all her computer resources and knowing that Colonel Nozzaire isn't seriously looking for her uncle, she turns to the only person in the world who might be able to help - the now retired and gadget-phobic Brain.

Gadget is sent to Neutralia, the world's only source of the supermetal neutronium, to rescue King Olaf who has supposedly been kidnapped by the ghost of King Thor. It turns out that Thor seems all too real and intends to take over the country and give MAD the neutronium so Dr Claw can build an invincible army.

Colonel Nozzaire (pronounced Nosehair according to the Colonel) is captured by aliens who think that he is Gadget. They do tests to see if he is Gadget, which he fails. Gadget tries to find him, but when he finds the aliens, he doesn't realize who they are. When the aliens trick Gadget onto boarding their ship, when find out they have a deal with Dr. Claw where they'll exchange Gadget for the moon. One of Claw's agents tells them that Gadget is really dangerous, so the aliens put a device on Gadget that will reverse his brain waves. Thinking that he is really smart, but acting stupid, they put it on him. Gadget ends up being really smart and saves the day by stopping Claw and telling the aliens that no one owns the moon, so they can live there if they want.

Colonel Nozzaire decides to follow his therapist's advice about reducing his stress level and fires Gadget but Gadget thinks he's being sent undercover. After a couple of disastrous menial jobs, he's hired by a Temp agency that's a front for MAD to send him to do their dirty work under the guise of doing odd jobs.

The Colonel is taking his first vacation in twenty years, so it's Gadget mission to protect him from any MAD agents and let him have a good time.

Dr. Claw hires two corporate headhunters to find him the ideal second-in-command and they use Halloween as cover to invite candidate criminals to a Halloween party in a trap filled house so they can be tested. Guess who stumbles into the party while trick-or-treating with Penny.

The reason Santa's workshop has never been seen by polar explorers is because it's located under the North Pole. Once a year, Santa opens the passageway to the surface, but this year MAD is waiting and takes over the workshop to begin manufacture of a MAD Agent kit designed to hypnotize all the kids in the world and turn them into junior MAD agents. On Christmas Eve, someone sends a report to WOMP but Colonel Nozzaire thinks it's a joke; however, Gadget still believes in Santa and heads for the North Pole stopping enroute at the Last Resort, the only hotel that far into the Arctic. Penny has stowed away in the Gadgetmobile and learns from Santa's undercover reindeer George that the resort is under MAD control just like Santa's Workshop and the MAD agents running it intend to dispose of her uncle before he makes it to the North Pole. Can Gadget save Santa and Xmas before it's too late?

One of Dr Claw's MAD scientists creates a cloning machine that creates evil duplicates and plans to use it on the World Leaders meeting at a summit in Paris. Since Gadget is head of security the scientist creates a duplicate of him to abduct the world leaders so they can be copied while the real Gadget is dumped into a quicksand pit which he thinks is a spa mudbath. Penny is captured by the duplicate Gadget so it's up to Fidgit and Digit to save the day without her advice.

Dr. Claw tries to take over a petroleum rich country where wrestling is the national sport by planning to stage a coup when the King attends the Royal Wrestling Championship. Colonel Nozzaire (who was having a pleasant daydream about Gadget's funeral at the start of the episode) sends Gadget undercover to investigate the Championships.

In England, people whose homes have been ransacked keep turning up wandering the streets in their nightclothes with no idea how they got there. Gadget is sent to investigate but has become sidetracked with trying to sell toystores the handcarved toy soldiers the hospitalized Colonel Nozzaire has been making to relieve his stress. The toy stores aren't interested because all everyone wants is the hot new toy The Wuzzley. While Penny thinks it's cute, she's noticed a connection between it and the robbery victims. Now, if only she can figure out how to get her uncle to investigate.

Gadget is sent to investigate Bigfoot sightings which he thinks are a hoax but will give him the chance to enjoy some camping; but there's something roaming the mountains.