After a jetliner crashes Melinda faces the overwhelming task of helping hundreds of passengers crossover. While Melinda faces this task she finds that the “Wide Brim Man” is working against her. Melinda must also try to work with the crash investigators who are trying to find out how Melinda knew that the plane was going to crash.

Andrea’s friend has gone missing during a hike and Melinda’s called in so she can use her abilities to find him.

Melinda comes across the spirit of an infuriated young boy, who's terrorizing his mother and baby sister.

Melinda experiences a sense of dread when she realizes that a plane is going to crash when the spirits of the pilot and flight attendant contact her.

The ghost of an elderly man suspects Melinda's new neighbor of killing his granddaughter.

Melinda must help the ghost of an African-American man who had been attacked and killed by a white co-worker in the 1970's. The ghost is haunting the prosecutor who had enough evidence but still failed to file charges against the white co-worker. Melinda tries to help the ghost find justice and help his son to change his racist views before they're passed on to the next generation.

A boy who was killed in a collision with a train wants Melinda's help to ensure his mother that his death was not caused by her.

Sam has a brush with death as he risks his life to save Melinda from harm.

After a stand-up comedian commits suicide, he's left in between worlds. Melinda tries to help him find closure.

When a traveling circus arrives, Melinda meets the bitter ghost of a magician who accuses his envious brother of his death, deemed to have been accidental.

A head injury caused by an accident puts Melinda's abilities at risk. Melinda must deal with the possibility of permanently losing her gift as she attempts to help a young girl whose boyfriend has recently died.

Melinda and Jim go away on a romantic cruise and Melinda comes into contact with an angry ghost who haunts a newlywed couple.

Melinda worries that Andrea is being influenced not to cross over. Melinda seeks the help of an expert in history and the occult in helping to identify the wide brimmed hat man.

Melinda meets a man who has the same abilities to see and talk to the dead. Melinda later learns that he has a different plan for the dead. A ghost enlists Professor Payne to help Melinda.

Melinda visits the Mayor of Grandview and asks him to cancel the memorial dedication they are holding. She speaks to the ghost of a mail person and is looking for a young girl named Kristen. Later, Melinda and Professor Payne search for missing children after their Nanny says that they left with a man named Gabriel. Meanwhile, a mysterious man tries to get Melinda to stop helping the good guys.

Melinda helps a group of college girls after one of their friends dies and begins to haunt them. Melinda must get Rachel to believe she is not Bloody Mary.

Melinda's life is in danger when she tries to help the victim of a stalker.

Melinda discovers the truth about her family's past through a series of bodily possessions.

Dark forces are fighting for the soul of a little girl that cannot escape the haunted house she has been trapped in for years.

Melinda encounters the ghosts of three boys who died in the fire of an orphanage. They must cross over prior to the demolition of the building holding them inside.

An evil spirit is haunting Jim, causing him to begin doubting his sanity. Melinda must help this spirit, even though he is dangerous, in order to help Jim. .

The spirit of the mother of a teenage boy attempts to communicate with her son via white noise. Melinda must find a way to get her messages across.

Melinda and Jim become foster parents temporarily for a young girl whose mother is missing. The ghost of the mother comes to Melinda and tells her where Melinda can find her body. The mother confesses a secret to Melinda and Melinda and Jim set out to help the little girl.

Five accidents, and four signs, something else is going to happen. Melinda becomes concerned for the safety of the people she loves when a ghost prophet shows her visions of the future. The fellow Ghost Whisperer, who Melinda doesn't trust is still in Grandview.

Melinda and Sam's relationship hangs in the balance after Melinda shares some devastating news.