After a jetliner crashes Melinda faces the overwhelming task of helping hundreds of passengers crossover. While Melinda faces this task she finds that the “Wide Brim Man” is working against her. Melinda must also try to work with the crash investigators who are trying to find out how Melinda knew that the plane was going to crash.

Melinda experiences a sense of dread when she realizes that a plane is going to crash when the spirits of the pilot and flight attendant contact her.

Sam has a brush with death as he risks his life to save Melinda from harm.

Melinda and Jim go away on a romantic cruise and Melinda comes into contact with an angry ghost who haunts a newlywed couple.

Melinda is forced to remember how her relationship with her mother became strained after Melinda’s first ghost emerges. Melinda’s mother could not understand how to deal with Melinda’s gift. Melinda must reunite with her mother to help the ghost.

Melinda worries that Andrea is being influenced not to cross over. Melinda seeks the help of an expert in history and the occult in helping to identify the wide brimmed hat man.

Melinda meets a man who has the same abilities to see and talk to the dead. Melinda later learns that he has a different plan for the dead. A ghost enlists Professor Payne to help Melinda.

Melinda visits the Mayor of Grandview and asks him to cancel the memorial dedication they are holding. She speaks to the ghost of a mail person and is looking for a young girl named Kristen. Later, Melinda and Professor Payne search for missing children after their Nanny says that they left with a man named Gabriel. Meanwhile, a mysterious man tries to get Melinda to stop helping the good guys.

Melinda helps a group of college girls after one of their friends dies and begins to haunt them. Melinda must get Rachel to believe she is not Bloody Mary.

Melinda's life is in danger when she tries to help the victim of a stalker.

Melinda discovers the truth about her family's past through a series of bodily possessions.

Dark forces are fighting for the soul of a little girl that cannot escape the haunted house she has been trapped in for years.

Melinda encounters the ghosts of three boys who died in the fire of an orphanage. They must cross over prior to the demolition of the building holding them inside.

Five accidents, and four signs, something else is going to happen. Melinda becomes concerned for the safety of the people she loves when a ghost prophet shows her visions of the future. The fellow Ghost Whisperer, who Melinda doesn't trust is still in Grandview.

When a child's imaginary friend disrupts a wedding, Melinda tries to calm the ghosts causing chaos.

Melinda and Sam's relationship hangs in the balance after Melinda shares some devastating news.

Jim's hospital is being haunted by the ghosts of kids from an abandoned polio ward in the early 1900’s. And the connection of Aidan, Melinda, the Shinies and the Shadows will come to a climax and Melinda and Jim will realize that they know almost nothing about Aiden's powers.

Melinda and Jim become foster parents temporarily for a young girl whose mother is missing. The ghost of the mother comes to Melinda and tells her where Melinda can find her body. The mother confesses a secret to Melinda and Melinda and Jim set out to help the little girl.

Gabriel returns to Grandview and Melinda learns more about what is lurking below.

Melinda becomes involved with a couple of ghosts who refuse to cross over after she finds that they are causing trouble for another couple. The ghosts make Melinda play a game of twenty questions.

Melinda reveals her gift to Sam, but his reaction is not what she had expected.

A young woman in Eli's apartment building is being haunted.

Jim and Melinda's wedding is overtaken by an ambitious wedding planner while Melinda deals with dreams that seem to threaten her child. Elsewhere, Eli's ex, Zoe, is caught up in a book sale with tragic consequences.

When the ghost of a little girl who passed away from leukemia befriends Aiden and threatens Melinda to stay out of her way, Melinda worries for her son's safety.

A boy who was killed in a collision with a train wants Melinda's help to ensure his mother that his death was not caused by her.