With Godzilla seemingly dead, the team journey to Jamaica to help the U.S. military investigate the ongoing disappearances in Jamaica.

Shady promoter Maximillian Spiel entertains wealthy ticket holders with a series of “cage matches” between giant mutations like the Shrewster and the Giant Centipede. For his next bout, Spiel sets his sights on the “ultimate monster”… Godzilla.

From their secret base on Isle del Diablo, the aliens assemble their forces; H.E.A.T. desperately fights to resist.

Acting on confidential information from Phillipe, H.E.A.T. investigate an abandoned lab in the Amazon rain forest where, 50 years before, French scientists succeeded in creating a creature made of pure DNA.

While on a romantic cruise in Alaska, Nick and Audrey’s ship is attacked by a Giant Turtle.

As the aliens and their mutation allies attack Earth, H.E.A.T. escapes captivity. They battle to defeat the alien onslaught and free the mutations from their control to help humanity fight back and save the planet from conquest.

H.E.A.T. heads for Scotland after Dr. Hugh Trevor of the Pisces Marine Research Institute claims his facility was attacked by the Loch Ness Monster.

As tension threatens to break up the H.E.A.T. team for good, major problems arise: a Giant Bat is terrorizing the countryside of Nigeria, the U.S. military has dredged the Leviathan ship from the bottom of the Pacific, and worst of all, the aliens are back.

A trip to Japan to investigate a number of mysterious disappearances leads to a battle of wills between H.E.A.T. and the Japanese military, who perceive Godzilla to be a threat.

After Godzilla battles robotic insects, the team encounter their creator: Cameron Winter, a powerful technology mogul and an old rival of Nick's from college.

H.E.A.T. investigates the tropical island of Santa Marta in the wake of a devastating volcanic eruption. But what they find on the island is that, due to irradiated lava, a hideously mutated ecosystem has developed, including carnivorous plants and gigantic bees.

While Craven is laid up sick back at H.E.A.T. headquarters, Nick, Randy, Elsie and Monique assist Godzilla in a battle with a Mutant Jellyfish. The Heat-Seeker is engulfed by a mysterious storm which propels the team into a bleak, post-apocalyptic future where Godzilla is dead and the world is dominated by genetically engineered, 5-legged mutations known as Dragmas.

A traveling carnival arrives at Madison Square Garden, and it's run by a crooked ringmaster known as Theodore P. Bunkum, who specializes in putting various captured mutations on display for public amusement. Bunkum places a hefty bounty on Godzilla, determined to add this most famous mutation to his carnival side show, and this incites H.E.A.T. to attend one of his shows, where they are quickly appalled by his treatment of the various mutations featured in it.

While scouring the sewers of New York, Nick Tatopoulos discovers one of Godzilla's eggs has survived.

H.E.A.T. are called to help the Central America Republic of Costo Rojo to deal with "El Gusano Gigante", a mutant worm that is devouring untold amounts of crops.

A mutant giant rat emerges from the sewers of Manhattan.

The team are called to help a rescue mission for xenobiologist Alexander Preloran, who disappeared while on a mission to explore the Leviathan, an alien spacecraft buried at the bottom of the Pacific Ocean for 65 million years.

When villages in Mexico are attacked by a strange winged creature, ornithologist and Elsie's old fiancé Lawrence Cohen calls H.E.A.T. for help.

While conducting another creature investigation in the valley of Blind Rock, Wyoming, H.E.A.T. meets up with a girl whose brother went missing after he entered an abandoned mine in the area where the sightings took place. Upon entering the mine themselves, the group discovers one of the strangest mutations they have yet encountered, a huge two-headed kaiju known as the Silver Hydra, on account of the fact that it has the ability to spurt a silvery fluid that hardens once it surrounds a living being, thus transforming them into the equivalent of a silver statue, a fate that obviously befell the girl's brother.

H.E.A.T. is charged by the Pentagon to investigate the growing population of spiders near an Army base in the Canary Islands.

The Techno-Sentient, an alien piece of technology, falls to Earth and begins to bond with all manner of human technology, growing to gargantuan proportions.

Elsie is suffering from a family problem of a personal nature, along the lines of sibling rivalry: her sister's wedding is soon to take place, and she is chagrined due to the disproportionate amount of attention and familial adoration that her sister has received in contrast to her. Further, she feels that her family has little respect for her choosen vocation, i.e., her activities with H.E.A.T. [that must be quite a hard family indeed to show a lack of appreciation for a daughter who has routinely risked life and limb for her planet by investigating and battling dangerous, life threatening giant monsters, and even helping to thwart an alien invasion! Her sister must truly be the world's most talented ass-kisser].

While tracking Godzilla to Fort Armstrong, New Mexico the team discover a gigantic mutated scorpion, called Ts-eh-GO by the locals, is on the rampage.

In response to a sanitation workers' strike, a colony of petroleum-eating microbes, controlled by nanotechnology, are released to try to curb New York's garbage problem.

When a strange electrical creature known as the Crackler attacks seemingly random locations in Manhattan, the team investigate.