An urgent case involving a liver transplant between a father and son is brought to Ik-jun's attention. Jun-wan has big news for one of his patients.

Worries about Ik-sun plague Jun-wan's ever-busy days. While watching over a patient post-surgery, Heo Seon-bin experiences a critical lesson.

Jeong Rosa fears the worst when her memory continues to decline. Song-hwa grapples with the unforeseen diagnosis of a loved one.

The five friends leave for vacation together, but not all of them make it to the destination. Jae-hak and his wife navigate one surprise after another.

One of the hospital's doctors is rushed into the emergency room. A patient with an unanticipated condition poses a challenge for Song-hwa and her team.

Gyeo-ul receives a disturbing noise complaint about one of Ik-jun's patients. Seok-hyeong opens up to Song-hwa, who gives him a piece of advice.

From student to intern for Yun-bok and Hong-do, and resident to fellow for Gyeo-ul, every step forward comes with plenty of hiccups — and new learnings.

A hospital ping pong tournament brings out each department's competitive streak. Ik-sun and Jun-wan make plans to meet for a proper chat.

A series of tough choices and sudden crises keeps life at the hospital as busy as ever. Through it all, the five friends continue to follow their hearts.

Kim Jun-wan waits for a response from Lee Ik-sun, who says she needs some time. Jeong-won breaks painful news to the family of his longtime patient.

An unforeseen problem just before a surgery forces Jeong-won to make a tough decision. Meanwhile, Jun-wan is put on edge in the operating room.

Distracted by a problem in his personal life, Do Jae-hak struggles to get through the day. Meanwhile, Chu Min-ha finds herself drowning in work.

Put in a stressful situation, Jae-hak looks to Jun-wan for advice on the right thing to do. Ik-jun accidentally uncovers an extraordinary secret.

Ik-jun handles a sensitive request from the troubled wife of a patient. A sudden piece of news threatens Seok-hyeong's peace.

As doctors and as humans, the five friends each face a maze of life's questions and decisions as they figure out their next steps.

Ik-jun’s team deals with a patient’s anxious brother — and his overbearing attitude. Chu Min-ha leaves a bad impression on a visitor in the cafeteria.

Jang Gyeo-ul can't get one kind word out of Ahn Jeong-won, who seems especially cold to her. A difficult professor joins the cardiothoracic department.

An urgent call sends Song-hwa rushing to the hospital to tend to a young patient. Ik-jun receives a plea from a desperate father.

Traveling to and from Seoul, Song-hwa takes on a VIP client in need of surgery. A woman with pregnancy complications fights to keep her baby alive.

The hospital's med students are inspired by the doctors, who each look after their patients in their own ways. Lee Ik-jun gets a welcome visitor.

Yang Seok-hyeong's aloofness frustrates someone on his team. Jang Yun-bok and Jang Hong-do witness a surprising side of Song-hwa outside the hospital.

As life at the hospital goes on, the five friends' growing pains continue. Gyeo-ul is disquieted by frequent visits from a patient's mother.

For the first time in 20 years, everyone's finally working under the same roof. A patient with a familiar name finds Chae Song-hwa.

Five friends whose friendship goes back to their days in med school are brought back together when a phone call interrupts each of their busy lives.