Lyle Menendez speaks from behind bars to Chris Cuomo, more than 25 years after he and his brother Erik were convicted of first degree murder.

On October 25, 1994, Susan Smith reports that a carjacker has abducted her two young sons, Michael and Alexander. This report sets off a nationwide search for the boys. While the world waits for news about the boys, investigators deliver shocking news.

For nine days, the nation waits for news as to the whereabouts of missing 3-year-Michael and 14-month-old Alex Smith. Then, there's a shocking break in the case. The boys' father, David, shares his heartbreaking story.

Authorities search for missing mother of two, Susan Powell, in every nook and cranny of the desert in Western Utah while her friends and family wait for a break in the case. Her husband Josh is named a person of interest as suspicion about his involvement in her disappearance grows. He and his father wage a counter-attack and a war between Susan and Josh's families erupts in the glare of the public spotlight. Shocking revelations about Josh and his family come to light--evidence of violence, obsession and sexual perversion. The family drama leads up to a shocking and unimaginable conclusion.

Recent scientific advances have uncovered new secrets around the Titanic sinking, challenging previous notions about the ship's fate. This chapter continues to analyze the wreck and a recent underwater expedition that claimed more lives.

The fateful Titanic shipwreck of 1912 intertwines with a recent underwater OceanGate voyage that cost more human lives. Interviews with historians, wreck analysts, and descendants of Titanic passengers shed light on both tragedies.

HLN highlights the shocking motive that turned these brothers into killers.

Saint Patrick's Day 1990, robbers stormed Boston's Gardner Museum, making off with 13 priceless artworks, never to be recovered. Valued at half a billion dollars, the whereabouts of the missing pieces remain a mystery.

David Kaczynski, the brother of convicted Unabomber Ted Kaczynski, discusses the hunt that led to the capture of his infamous sibling.

Deborah Jean Palfrey threatened to expose names on her client list and was found hanging on her mother's property.

Actor-musician David Cassidy ("The Partridge Family") experiences the pressures of fame as a teen idol in the 1970s. In the end, his death is surrounded by mystery, leaving his family, friends and fans with more questions than answers.

In an exclusive prison interview, Timothy McVeigh himself describes how events in his personal life - and in the ever-changing world around him - inspired him to take action against his fellow Americans.

In the dark hours of June 23, 1993, in Manassas, Virginia, a man lies fast asleep on his bed, while a woman looms over his prone body with a kitchen knife and proceeds to slice off his manhood. A stunning end to the broken marriage of Lorena and John Bobbitt, but what outrageous situation led two young people to a horrifying silent scream in the night?

On Oct. 28, 2007, 23-year-old Stacy Peterson, the wife of veteran police sergeant Drew Peterson, goes missing. As police launch an intensive search to find Stacy, the case raises shocking new questions about her husband.

On April 19, 1995, Timothy McVeigh, a 26-year-old U.S. army veteran, detonated a 7,000 pound truck bomb outside the Alfred Murrah Federal Building in downtown Oklahoma City, claiming the lives of 168 innocent people.

Susan Powell, a 28-year-old mother of two, goes missing in December of 2009. Her husband Josh claims to have taken their two young sons winter camping in the Utah desert and says he returned the next day to find her gone. Questioned by detectives, he doesn't behave like a concerned husband and his version of events doesn't match his son's. The mystery about where Susan's is deepens as more details about her marriage to Josh and their life behind closed doors emerge. Susan's family and friends do everything they can to find her while Josh insists that she ran out on him and their two little boys. The search for Susan Powell plays out on a national stage with everyone wondering: did she run off? Was she taken? Is Susan Powell dead or alive?

Uncovering Prince's secret struggles from his earlier years to the final days leading up to his shocking death.

Examining the factors that led to the crash that killed John F. Kennedy Jr. and a never before seen interview with a person who may have been the last person to speak to JFK Jr, moments before the crash.

The chilling account of a man who survived his encounter with the notorious serial killer, who managed to evade police scrutiny for years.

Heath Ledger's death is examined.

Uncovering how Anna Nicole Smith's lavish lifestyle may have contributed to her mysterious death.

Revelations of what Michael Jackson's children and staff witnessed prior to his death.

Revelations of what Michael Jackson's children and staff witnessed prior to his death and an investigation into the claims that Jackson took his own life.

Investigating a wide range of suspects and evidence in the killing of JonBenet Ramsey.

The aftermath of the investigation into the murder of JonBenet Ramsey.