In the slums of Bhopal, a failed drug with disastrous side effects, S93R, finds its way into Mangu's family. Dr Saira Sabharwal joins Manthan hospital and challenges the status quo.
The drug trials cause adverse effects on Dr Vivek Shekhawat's patients. At Manthan, Dr Shindey and Dr Gauri Nath lock horns over the latter's dream project.
As Deepali's past and her connection to Roma is revealed, Gauri gets challenged by the Chief Minister and Dr. Shindey. Mangu takes a risky step to save his mother.
While Saira's husband, Neil, begins his assignment on the Bhopal gas tragedy, Gauri decides to topple the CM. Tired of his situation, Mangu involves Deepali in his next move.
With Gauri's plans moving closer to fruition, Deepali struggles as the experiment advances to the next stage. Saira's home life takes a hit when Neil questions her.
