After Anne Bailey's husband is killed by Native Americans, she defies the social norms of the frontier and becomes a horseback courier, risking her life to deliver vital supplies to isolated forts and settlements.

Naturalist William Bartram risks his life exploring the unmapped regions of the South to document the native fauna and flora. Over thousands of miles of terrain, he faces hostile Native Americans, dangerous wildlife, and deadly disease.

Legendary frontiersman Daniel Boone faces the biggest challenge of his life when the Shawnee take him as their prisoner. If he can't escape, he won't be able to warn the settlement of Boonesborough, and his family, of a looming attack.

Astronomers Charles Mason and Jeremiah Dixon brave deadly terrain and hostile Native Americans to resolve a border dispute in Colonial America. With science and courage, they survey their famous Mason-Dixon Line with pinpoint accuracy.

When frontiersman James Harrod founds Harrod's Town on Native American hunting grounds, he soon finds his new settlement under attack. His leadership is tested as he defends the first European settlement west of the Appalachian Mountains.

After successfully mapping the rugged Ohio Country, frontiersman and surveyor Christopher Gist is hired to lead a young George Washington on a perilous diplomatic journey to deliver an ultimatum to the French forces in the Ohio wilderness.

When Chief Pontiac organizes a coalition of Native American tribes to attack British forts, frontier trader George Croghan risks his life on a perilous journey into the wilderness to find Pontiac and attempt to negotiate a peace agreement.

Robert Rogers leads an elite fighting force of fearless rangers behind enemy lines to fight French forces in Colonial America, but one mission tests his men as never before when they must trek 200 miles through the wilderness without food.