A mysterious arm reawakens the Greeed from their slumber and decides to use Eiji Hino, a cheerful wanderer, as his means of getting back what he desires as Kamen Rider OOO.

Ankh explains the Greeed and the purpose of the Medals to Eiji, even as the human desires to merely use his new power to fight for good instead of for selfish needs.

Ankh becomes troubled when Eiji prevents him from eliminating his possessed body's sister while another Greeed uses a man's gluttony to create more Medals.

Ankh threatens to leave OOO for Kazari and the Greeed while investigating the evolution of humanity while Eiji tries to find more about Hina.

Kougami asks for a share of Eiji and Ankh's Medals, while Mezool decides to use Hina's shopaholic classmate to create a new Yummy.

Hina confronts Yamano's shopping addiction when her father goes bankrupt while Ankh confronts Kougami about his share deal of the Cell Medals.

Eiji tries to research a husband bullied by his wife that is being mocked by Gamel while Ankh follows a lead for a missing Core Medal.

Eiji gets to the root of the Komoris' problem involving greed and loss of ambition while Ankh fights for survival after a failed confrontation with Uva.

A serial bomber tied to a nest of Yummies leads to Eiji to reveal his past to Hina and forces him to encounter a strange man he believes is Mezool's victim.

Eiji must figure the means of stopping the mad bomber and his Yummies to prevent any more lost lives, even with Maki observing the creation of his worker's monsters.

Eiji's traveler friend becomes manipulated by Uva into becoming famous as he steals others attributes; while Gotou doubts Eiji's effectiveness as OOO.

Eiji teaches a lesson to Tsukuba and Gotou about going forth to gain what is desired; while Ankh tries to figure a way to manage the flying Ageha Yummy using Gamel.

Ankh becomes sick of dealing with the problems of working with Eiji as Kazari targets a famous surgeon who believes she is not getting the treatment she deserves.

Eiji rushes to find Ankh to save Shingo's life while Tamura discovers the truth about what it means to be a surgeon.

Kazari uses a transport truck of Cell Medals, a Core Medal of Ankh and a captured Hina to lure all sides into a free-for-all showdown.

Maki and Kazari experiment with Gamel in determining the use of a Greeed for a Core Medal container as Eiji approaches Kougami in finding out more regarding the artificial beings.

Eiji and Ankh try to figure out Akira Date, the man who has become Kamen Rider Birth, as Uva creates a peculiar Yummy from a kendo girl who wishes to be stronger.

After a second Yummy splits off from the original with a different motive, Eiji and Akira must work to figure the true desire Rie held in order to figure how to truly destroy the creation.

Kazari creates an "evolved" Greeed using the desires of a convict to get back at a traitorous hoodlum and Shiro in order to pursue Ankh.

After being abandoned by Ankh desiring the return of one of his Core Medals from Kazari, Eiji is found by the cowardly hoodlum Yasu while he continues to ponder if his partner can really be trusted.

Uva uses the desires of a troubled father to serve justice for the sake of his son to create a Greeed that assist him in creating this desire.

Eiji and Shintaro work to try and stop Susumu and his son from going too far as they use the power of their Yummy to attack greater targets for the sake of justice.

Akira decides to bond with Eiji to investigate his travels while Kazari slowly awakens the sleeping desires within the scientific sister of a beauty company president.

As Eiji becomes smitten with the elder Yumi sister, Akira tries to reach out to her sudden obsession with being the most beautiful under her awakened desire.

Ankh starts acting suspicious when a new bird Yummy emerges created to help a washed-up boxer stand in the ring once more.