Seth takes a closer look at Republicans coming up with increasingly insane arguments against Biden’s vaccine requirements before speaking with Amy Adams and Lee Daniels and welcoming musical guest girl in red.

Seth’s brother, Josh Meyers, delivers a message to Californians as California Gov. Gavin Newsom about winning the recall election before Seth speaks with Bill Burr, Keith Morrison and Abby McEnany.

Seth takes a closer look at progressives in Congress pushing forward with a transformative $3.5 trillion climate spending plan before speaking with U.S. Special Presidential Envoy for Climate John Kerry and Jim Gaffigan.

Seth takes a closer look at stunning new details about a memo one of Trump's lawyers wrote on how to overturn the results of the 2020 election, then speaks with Ike Barinholtz and Jenny Slate.

Seth takes a closer look at Fox News banning Rudy Giuliani as both Giuliani and the network face defamation lawsuits, then speaks with Billy Bob Thornton and Miriam Margolyes.

Seth teams up with Amber Ruffin and Jenny Hagel for a brand-new Jokes Seth Can’t Tell, then speaks with Ray Liotta, Natasia Demetriou and Spencer Ackerman.

Seth takes a closer look at centrist Democrats holding Biden’s agenda hostage while Republicans threaten to crater the economy, then speaks with Demi Lovato and Neal Brennan before welcoming musical guest Audrey Nuna featuring Saba.

Seth takes a closer look at two centrist Democrats blocking the entire Democratic agenda without saying what they want, then speaks with Colin Jost and Michael Gandolfini.

Seth takes a closer look at progressive Democrats staging a collective show of force against the two Senate moderates holding up President Biden’s agenda, then speaks with Blake Griffin and David Chase.

Seth checks in with his monologue writers and holds a surprise inspection to review the quality of their jokes, then speaks with Jason Momoa & Dave Bautista, Alessandro Nivola and Anthony Doerr.

Seth takes a closer look at Facebook’s disastrous week before speaking with guests Blake Shelton and Brett Goldstein and enjoying a performance by musical guest Cuco.

Seth takes a closer look at the damning new details of Trump's coup attempt before celebrating speaking with Ted Lasso’s Jason Sudeikis, Brendan Hunt & Joe Kelly.

Seth takes a closer look at Rep. Steve Scalise refusing to say the 2020 election was not stolen before speaking with Ron and Clint Howard as well as Hillary Clinton and Louise Penny.

Seth lets Amber Ruffin respond to President Trump saying he’s done more for religion than any other president before speaking with Sen. Elizabeth Warren, Succession’s Matthew Macfadyen and comedian Rickey Velez.

Seth takes a closer look at Republicans falsely blaming Biden’s vaccine mandate for Southwest’s chaos before speaking with guests Chris Hayes and Sarah Snook.

Seth takes a closer look at a possible criminal referral for Steve Bannon and Trump telling Republicans not to vote before speaking with James Spader and enjoying a performance by musical guest Tate McRae.

Seth takes a closer look at a bombshell new report that ties GOP members of Congress to the January 6 insurrection before speaking with guests Anderson Cooper and Cobie Smulders.

Seth lets Late Night writer Amber Ruffin perform a special song about Halloween before speaking with Amanda Seyfried and Rebecca Ferguson and enjoying a musical performance from Broadway's Caroline, or Change.

Seth takes a closer look at GOP members of Congress facing growing scrutiny over their roles in the attempt to overthrow democracy before speaking with guests Beanie Feldstein and Norman Lear and enjoying a performance by musical guest Lady A.

Seth takes a closer look at Democratic leaders and President Biden claiming they have reached a deal on a framework for a massive bill before speaking with Olivia Munn, Roy Wood Jr. and Jason Blum.

Seth takes a closer look at Republicans fully embracing Trump as he still tries to cover up what happened on January 6 before speaking with guests Tracy Morgan and Colin Quinn.

Seth steps away from bleak and depressing news to share a news story before speaking with Willie Geist, Steve Schirripa & Michael Imperioli and Fortune Feimster.

Seth takes a closer look at beltway insiders ludicrously blaming progressives for Republicans winning in Virginia last night before speaking with guests Keri Russell and Joe Pera and enjoying a performance by musical guest Jake Wesley Rogers.

Seth takes a closer look at Republicans hoping to repeat the strategy they used in Virginia in the 2022 midterms before speaking with Kumail Nanjiani and Jonathan Majors.

Seth takes a closer look at Rudy Giuliani admitting in a deposition that he didn't try to verify his insane voter fraud lies, then speaks with Pete Davidson and Emily Ratajkowski.