Mirtha Macri must overcome challenges to deliver her child. David fights for his team's expansion while a colleague receives a devastating diagnosis.

John's team deals with the crushing loss of a beloved patient. Mitch returns to work. Amanda comes to grips with a new development in her pregnancy.

Halloween keeps the ER busy while the neurosurgeons operate on a young Brazilian woman whose surgery is prolonged by surprising lab findings.

The neurosurgery team retreats to David's beach house, where Mitch Levine shares his news. Amanda's husband inadvertently reveals the baby's gender.

John Boockvar gives a family a grim update. David performs Mitzie's delicate procedure. The two doctors recall how their fathers shaped their careers.

An up-close depiction of the overwhelming spread of COVID-19.

Amanda Little-Richardson copes with a rare diagnosis for her unborn baby. David Langer's flawless brain surgery on Mitzie has an unexpected result.

A tough delivery has a happy outcome for Amanda, who prepares to leave New York. John's patient faces the end as David's team continues to grow.

Two neurosurgeons, an ER doctor and an OB-GYN fight to give their patients quality health care despite professional and personal challenges.