Fresh off "Sesame Street," Big Bird squares off against actor Jason Schwartzman.

Actor-rapper Pooch Hall takes on his "Ray Donovan" on-screen brother, Dash Mihok.

Serena Williams guest stars in a husband vs. wife battle as tennis legend Andy Roddick takes on actress and supermodel Brooklyn Decker.

American Ninja Warrior hosts Matt Iseman and Akbar Gbaja-Biamila go head to head and battle it out in the ultimate arena, the Lip Sync Battle stage.

It's a "Superstore" super battle when Ben Feldman battles co-star Lauren Ash for the LSB Championship belt.

Legendary diva Mariah Carey graces the stage as Darren Criss ("Glee," "American Crime Story") takes on rapper Jermaine Dupri with amazing performances of their favorite Mariah songs.

Special guest John Legend joins the crew as singer/songwriter Andy Grammer takes on "Riverdale's" Vanessa Morgan, and they battle it out for the LSB championship belt.

The "Queer Eye" Fab 5 grace the stage in an epic battle.

Husband Boris Kodjoe (Station 19) and wife Nicole Ari Parker (Empire) battle on the LSB stage as they square off for household bragging rights and the LSB championship bel

Actor Nico Tortorella ("Younger") squares off against co-star Molly Bernard.

It's a small-screen battle royale as Brandon Micheal Hall of "God Friended Me" takes on "black-ish" star Marcus Scribner for the Lip Sync Battle belt.

Prince Royce and singer-internet sensation Lele Pons heat things up on the stage as they compete for the coveted championship belt.

It's a battle for the ages as Serayah ("Empire") takes on Rotimi ("Power")