When a radical group called The Watchdogs emerges with plans to eliminate the Inhumans, Agent Mack and his brother become caught in the crossfire. Meanwhile, Simmons discovers a powerful chemical compound that could alter the future for Inhumans.

Scattered across the galaxy, the team works to find their footing in the wake of losing Coulson.

After finding themselves in yet another gambling dilemma, a mysterious stranger offers Enoch and FitzSimmons a ride home where, it turns out, two shrikes aren’t better than one.

Coulson and the Agents of S.H.I.E.L.D. are thrust backward in time and stranded in 1931 New York City. With the all-new Zephyr set to time-jump at any moment, the team must hurry to find out exactly what happened. If they fail, it would mean disaster for the past, present and future of the world.

Coulson and his S.H.I.E.L.D. agents travel to Peru to investigate an object of unknown origin, codenamed 0-8-4. But when he runs into Comandante Camilla Reyes, more than just sparks fly at 30,000 feet.

Coulson and his team are haunted by a ghost that threatens to destroy them all, and only a secret from May's past can save them.

Hunted and running out of solutions, Phil Coulson puts his team right in the line of fire in the hopes of saving them all. But with General Glenn Talbot, HYDRA, and Carl Creel all on the attack, can they possibly survive? Meanwhile, a mysterious Doctor harbors some dangerous secrets that could destroy one of our core team members.

Coulson and General Talbot are forced to team up and attend a worldwide symposium on Inhumans, where they suspect Malick has an inside man. As the S.H.I.E.L.D. team gets closer to the truth, an unexpected traitor is revealed.

Daisy goes to battle Ghost Rider at a terrible cost, and Coulson faces the new Director, and his bold agenda surprises them all.

While Fitz and Enoch struggle in space, Sarge and his team move forward with their mysterious mission on Earth.

After being unexpectedly stranded in 1982, Mack retreats to his childhood home to process the death of his parents, while Deke gets to work scouting a chart-topping group of new agents. With no idea if or when the team is coming back for them, time seems to finally be on their side … at least until the killer robots show up.

When the brilliant scientist, Dr. Franklin Hall, is kidnapped, Agent Coulson and his S.H.I.E.L.D. agents must race against the clock to locate him. Skye is their only way in–pushing the team to their limits when the entire plan turns upside-down.

An elusive girl in a flower dress may hold the key to the mystery that brings Coulson and team to Asia to rescue a young man with an unusual and dangerous power; and Skye has a secret that jeopardizes her relationship with the team right when they need her most.

In the aftermath of his trip to Maveth, Coulson is more determined than ever to get to Gideon Malick and put an end to HYDRA once and for all. Daisy and the team encounter more Inhumans who have powers like they've never seen before, but will they be friends or enemies of S.H.I.E.L.D.?

It’s a wild night out on the planet of Kitson for the agents. While Leo and Enoch try their luck at the casino, nearby, Daisy and Simmons find themselves in a much... groovier situation.

Yo-Yo and Keller take things public; parasitic aliens threaten the human race; and someone really needs boba.

Sarge has May; Atarah has Daisy, Enoch and Simmons; and now, there are two planets that need saving.

Out of answers and running out of time, the agents must face the ghosts of their past in order to move forward.

With the identity of the timeline-unraveling "thread" revealed, the team's mission to protect him at all costs leads each agent to question their own values. Is preserving the future of the world as they know it worth the destruction they could prevent?

With the Zephyr’s time drive malfunctioning, the team is quite literally hurling toward disaster and Yo-Yo may be their only hope. The only problem? To get her powers back, she’ll need to enlist the help of an old adversary and revisit part of her past long hidden away.

After Enoch’s sacrifice propelled them out of the time storm, the team arrives back in 1983 where Nathaniel and Kora are hard at work building an army of hand-selected anarchist Inhumans at Afterlife. When the agents split up to cover more ground, Daisy is tasked with protecting Jiaying and is compelled to confront her mother for the first time since her death; while the others quickly learn they’ll need to face yet another supercharged former enemy in order to stop Malick.

With the help of Kora on the inside, Sibyl and Nathaniel continue their fight to shape a dark new future for S.H.I.E.L.D., managing to stay one step ahead of the agents along the way. If the team is going to turn this one around, they’ll have to get creative, and maybe even a little out of this world.

After the events of The Avengers, S.H.I.E.L.D. Agent Phil Coulson assembles a small team of agents to investigate a mysterious group called the Rising Tide. In doing so, they encounter Mike Peterson, a man who has acquired superhuman powers.

Agent Coulson and the S.H.I.E.L.D. team try to track down a mysterious woman who has single-handedly committed numerous high-stakes heists. But when the woman’s identity is revealed, a troubling secret stands to ruin Coulson.

Dangerous secrets are being kept from Coulson's Team, and he works the system to save Ward and Fitz when they are sent on a Level 8 classified mission that may end in tragedy.