Allison's old flame, Clay Bicks, appears at her doorstep moments after dying, unaware that he is dead. When he accepts the fact that he's dead and will never get to be with the woman he loved, he decides he's going to stay in Allison's house so he can at least be close to her. This upsets Joe, and Allison decides that something must be done to get rid of Clay. Meanwhile, Allison shares a bunch of odd dreams with Bridgette, except Bridgette's dreams keep coming to her in the form of cartoons for some reason.

When Allison becomes a lawyer and Joe starts a new job, the Dubois family is forever changed on the series finale of Medium.

Joe brings a reluctant Allison with him to a party at a prospective employer's house. Later on, the employer's daughter disappears, leading Allison to connect her recent dreams about Paris to the disappearance. Now it's up to Allison to save the daughter, which coincidentally will also secure Joe a job.

Allison meets Meghan Doyle, Joe's new business partner. Meanwhile, her old car stops working and Joe surprises her with a nice looking used car. The car ends up being the center of a horrible unsolved crime though.

Allison has dreams that help Scanlon in his search to find out who killed a wealthy local drug dealer. Allison and Scanlon are dumbfounded when Allison's dreams lead them to a severely impaired man with a bullet stuck in his brain. Meanwhile, Joe's partnership with Meghan Doyle is put in jeopardy.

On the 100th episode of Medium, an infant is kidnapped and Allison investigates the disappearance. But when she becomes too obsessed with the infant, Joe starts to get worried about her. Meanwhile, Bridgette and Joe are surprised after Marie manages to play the clarinet without any issues even though she hasn't attended any classes, while Bridgette is struggling to play.

A series of mysterious fire-related deaths may be tied to Allison's dreams of a blaze. Allison must also think about where her professional career is headed, as Devalos starts thinking seriously about running for mayor.

Allison runs into the man who kidnapped her daughter in one of her dreams at the District Attorney's office. She learns that he is a "Good Samaritan" who witnessed a robbery and is fully cooperating. After learning that he has kidnapped multiple young women, Allison reaches a roadblock in her investigation that leads her to yet another unbelievable breakthrough in the case. Meanwhile, Joe tutors Ariel in math, which in turn brings Allison to another shocking discovery.

Allison has visions of a friend of Scanlon and Lynn DiNovi dying in a home mishap. This causes her to struggle with connecting some recent "accidental" deaths, consequently putting her own health in jeopardy.

After a neighbor is murdered, Allison's fears for her own family prompt her to install a high-tech talking burglar alarm, which she later suspects may be communicating with Marie. Also, Ariel meets a ghost who could help her get into the college of her choice.

When an animal rights activist working undercover at a farm goes missing, Allison befriends a pig that could hold the key to the woman's whereabouts. Also, Joe's special birthday gift from Marie leaves him wondering how she was able to obtain it.

When Allison gets a skin graft on her hand after a burn, she is puzzled when the same hand acts with a mind of its own, gesturing uncontrollably. Also, Bridgette keeps her real role on the soccer team a secret from her parents.

Allison helps with the location of a missing child. Afterwards she gets a vision about the child's future and is not sure anymore what she should do to help the child.

Delavos receives help from Allison when he investigates the murder of his friends sister. But the case is taken into an unexpected direction when when Allison's visions involves the friend's former husband and current spouse. On the domestic front, Bridgette finds herself in trouble at school when she is caught drawing pictures of her teacher in the nude.

Allison investigates when a brother and sister report the disappearance of their mother. Meanwhile, Joe's sister moves in with Joe and Allison after walking out on her husband Ryan, but Joe's father has advice from beyond the grave about her relationship.

When Allison's friend with cancer suddenly dies she suspects a hospital employee may be at fault. Meanwhile, Bridgette writes a story that closely follows what later happens at Joe's job interview.

While investigating a rash of murders, Allison sees floating symbols above people's heads, signs that she thinks could match them with their perfect mate. Also, Joe is put in a tough situation when one of his employees accuses another of sexual harassment.

When Allison begins having flashes to a specific time in the future, her sense of dread grows as she feels more and more powerless to stop a catastrophic event from occurring.

Suddenly unable to understand the spoken word, Allison's marriage shows signs of strain and she develops an unexpected friendship with a linguist. Unable to communicate with his wife, Joe reaches the limits of his patience being married to a woman who is a slave to her visions.

Allison's dreams question her brother's recent good fortune; the Devalos campaign sees Bridgette as an asset.

Allison questions her powers when her old boss asks for her help in selecting a jury that will reinstate the death penalty for a murderer/rapist. This causes Allison to suspect that she has helped put the wrong man on death row.

Allison's recurring dream about two young boys racing a train is analyzed by Dr. Leonard Cardwell, but Allison soon learns that he's involved. Devalos investigates the case of a 14-year-old who confessed to murder.

Evidence shows that a pilot is indeed guilty of his wife's murder. However, in Allison’s dream, when the pilot is put in jail, there is a plane crash where hundreds of people are killed. Should Allison put forth the evidence to land this guilty man in jail, or let him go free in order to save hundreds of innocent lives?

Allisons helps the District Attorney trying to find a missing brother of a close friend. She becomes paranoid about antiterrorist agents from the government. Joe gets uneasy when he suspects that Bridget might be communicating with a dead author.

Allison is called to help Devalos investigate the shocking death of a well-respected assemblyman, but for some reason she has visions of a young boy trapped in a well mixed in with her visions of the assemblyman. She must figure out what the dreams of the young boy mean because the dreams of the assemblyman alone aren't enough for her to solve the assemblyman's death.