After being separated from Lani for five years, her soldier-husband Noel tries to woo her back by telling her that he is resigned from the army. Lani takes him back, and they start a new life with their daughter Cristina. Everything seems to be going well for them until they find out that Noel is afflicted with leprosy.

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Fatherhood takes a traumatic turn for Ruben after his wife abandons him for another man and confesses that the son he raised since birth is not biologically his own. This bitter fact provokes Ruben's anger that inevitably extends to the innocent boy, Benjie. But it is through Benjie's chaste love that Ruben learns that fatherhood exceeds the boundaries of flesh and blood.

Is blood really thicker than water or is there a remote possibility that justice can still prevail in the name of friendship? Can a mistake be rectified by vengeful violence? These are the questions that continue to plague Edna, whose simple but happy life shatters when the uncle of family friends Manny and Malou guns down her husband Rod in broad daylight.

To see her perfect home go down in shambles was a remote possibility for Sandy until her husband brought home a son he sired with another woman. Unwilling to sacrifice her peaceful family life and aware that the boy is innocent, Sandy tries to get over the past, but she realizes that it is difficult to coexist with the living proof of Danny's infidelity.

After the death of her parents, Rosing carries the burden of taking care of her mentally ill sister Amanda. She works hard to fend for the two of them, oblivious to the time passing by and her husband slipping away. While taking out her frustration on her mentally disabled sister, Rosing's philandering husband Emil returns to her. Rosing hopes of better days ahead until Emil assaults the helpless Amanda.

During a dark period in her past, Linette was convinced an abortion was her only chance to escape a failed relationship with a married man and to pursue a career in music. She finds new happiness in her mentor, David, whom she eventually marries. But Linette's life strikes a sour note when her past mistake catches up on her, and she becomes incapable of fulfilling David's dream to start a family.

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Marlyn devotes her life, even foregoing romance, to Louie, the abandoned child of her cousin Edith. But amidst her happiness as Louie's surrogate mother, she finds love and a prospective partner in Ronald. Life couldn't be better for Marylyn until Edith returns to reunite with Louie and her former lover who turns out to be Ronald.

Alvin was born with a silver spoon in his mouth, but he grows up unhappy in spite of his extravagant life. He trades luxury for a modest life as a truck driver and to be with the woman he loves. Though they work hard each day in order to get by, Alvin and Gigi are happy, until the wrath of Alvin's wealthy father wrecks their joy. Gigi's life is endangered by a terminal illness, and Alvin's father refuses to shell out a single cent to help them.

Terry is an old maid by choice, and Rocky is a playboy at heart. When they met, sparks flew, but their diverse personalities made romance a distant possibility. As a result, Rocky contented himself as Terry's employee, but an impassioned encounter left them in a compromising position. Rocky expressed his willingness to commit, but Terry wished to remain in her comfort zone until her sister's breakup with a longtime beau opened her eyes to the definition of a fulfilling life.

Though orphaned at an early age, Esther is blessed to be adopted by her kind godfather Alfredo. She grows up close to him like a real daughter and even ends up marrying his son Eric. While building a new married life with Eric, Esther sadly watches Alfredo's marriage turn sour because he suspects that his young, second wife is unfaithful. While helping her godfather keep his sanity, Esther comes close to losing hers when she learns that her own husband is the source of Alfredo's marital woes.

Smart and beautiful Christy's perfect life and career suddenly crumble because of imperfect choices, particularly in her choice of mate. Her marriage to Axel turns her into a mother and a homemaker patiently adjusting to her husband's measly income. When the opportunity of a bright career comes to her again, Christy deems this as a chance to give her family a comfortable life. She is unaware that this dream is about to turn into a nightmare.

Almost in his thirties, Ramil has never been in any romantic relationship. His mother attempts to arrange a date between Ramil and a girl from a prominent family, but his heart is won over by the very first woman he made love with- Salve, a prostitute. Despite the insults from his mother and his friends, Ramil marries Salve, and their happiness together seems to obliterate her dark past. But with Ramil's business down the drain and Salve's mom in a critical illness, can Salve resist the call of her old trade?

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For more than a decade, Nadine has proven her worth as a dedicated housewife and mother. Now that her children are all grown-up, Nadine gives in to her longtime dream of getting a job. Although Nadine's decision causes a rift with her husband Butch, she soon finds fulfillment in her role as a working mom. As Butch grows more stubborn with the adjustments in their home, Nadine fails to foresee that going after her own happiness would cause her own family.

Patty is thrilled at the prospect of experiencing her very first summer love, but she is doomed to spend a vacation at the house of her father's new wife whose son, Jet, gets on her nerves. While their parents are away on a trip, Jet and Patty get to know each other and find out that their unpleasant first impressions are wrong. Patty's dream of first love begins to take place, but never in her wildest imagination did she think that it would be her surrogate brother.

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Sibling rivalry is common among children, but in the case of Dolor and Lourdes, this problem goes on to their old age, affecting their marriages and their own children. Dolor is younger but more mature in her relationships. Her source of happiness is her husband, son Dennis, and their simple but happy home. Lourdes, on the other hand, marries for money and spoils her only son to taunt Dolor and the latter's incapacity to buy nice things for her son.

Benjamin is not bothered by the fact that his friendship with his gay professor, Joey, is mocked by people in school. The jokes turned into nasty rumors and resulted in their unjust suspension. Benjamin turns to his family for support but his homophobic father's response aggravates the situation. While trying to prove that his friendship with Joey is pure, Benjamin discovers a dark secret involving his father.

Several years ago, Sonia is a hair's breadth away from bliss as her longtime boyfriend, Jake, promises to marry her. Now, she is miserably raising her daughter, Annie, alone, and to make things worse, Sonia takes out her anger on the innocent child. Rumors of Sonia's ruthless abuse of her daughter reach the knowledge of a police detective. The investigation begins and the only way Sonia can justify herself is by going back to the dimmest chapter of her wretched past.

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