McCauley and two astronomers are on the Moon on Christmas day, and one of them is stricken with appendicitis.

His family watching from mission control, Col. Edward McCauley who is commanding the first rocket into outer space must make a desperate gamble when the second stage of his rocket fails to jettison.

Senator Jim Sloane questions the need for and cost of a mission to the moon after McCauley's first effort to the moon fails and his second effort leaves a crewman seriously injured during takeoff.

McCauley races against time in order to save an astronaut who is trapped when assembling the prefabricated units of a space station. The astronaut is the son of a air force general and trapped when his sleeve catches between sections of the space station.

When an astronaut is stricken by a heart attack on the Moon, McCauley must find a way to get him back to Earth.

When an experimental nuclear-powered missile goes out of control, its creator insists on accompanying McCauley into space to try and disarm it before it can strike the moon and wipe out a twelve-man expedition.

Trailblazer I is on route to the Moon when one of the crew gets word his wife has been hurt in a car wreck. Although distracted, the crewman needs to focus all his skills and abilities to overcome a major accident.

Returning from the Moon with valuable spore samples the crew of MR7 are rendered unconscious. Earth sends a rescue mission but a decision has to be made that could put everyone's life at risk.

An asteroid straying close to Earth becomes the subject of an experiment. It is decided to scout the asteroid with a view of turning it into a mobile space station. If not the rock must be destroyed.

Shortly after leaving the Moon a spacecraft is hit by an asteroid destroying their oxygen supply. The three man crew now become engaged in a life and death battle to extend their oxygen supply long enough to make it home.

Test continue on a new alloy for re-entry. On one test the ship acts erratically and although the crew is saved the ship is lost. A second mission is launched to try and understand what went wrong.

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Two scientists who can't get along are assigned to the same space station, and McCauley has to keep the peace.

It is decided to attempt fuel transfers between space craft while flying in orbit. The requirement for precision control of two spacecraft is met by using a pair of specially trained twins. Safety is the primary concern, but ensuring this, they overlook one potential fatal flaw in the mission

Col. McCauley is training a young cadet who wants to be an astronaut, and pushes the young man almost to his limit. When an onboard accident knocks out McCauley, the nervous young cadet has to bring the craft back to Earth on his own.

Four men a stranded after their spacecraft crash lands on the Moon. Their only hope of survival is to walk to Moonbase. All goes well till they realize the oxygen tank they are carrying to resupply themselves has a faulty valve. There is a way around the problem, but the cost may be too high for the team to accept

An eager, space-enthusiast technician (played by Robert Reed of The Brady Bunch) installs a smaller Guidance Control System he designed into the rocket ship. There is now room in the equipment bay for him to stow away on the next flight. But during the 12G takeoff his improvised couch crushes the equipment rack, causing the ship to lose all power before reaching orbit. The uncontrollable ship will quickly re-enter and burn unless repairs can be completed.

A mission is sent to explore a cave system on the Moon in the hope of finding ice. Having a source of water available would enable the colonization of the Moon.

A maverick journalist wins an opportunity to visit the Moon base. An opportunist he will look for anyway to manufacture a story, and his gambling habits put him at odds with the base commander.

A scientist's wife warns McCauley that her husband Perry's's co-worker Hal Carter is jealous of his success. McCauley doesn't believe her, but when Perry's theory about radioactive gas on the moon prove correct, Hal plots to kill Perry.

McCauley must take four scientists back to the moon to find a deposit of a valuable mineral that one of them stole, so that he can trick the thief into revealing himself.

Tensions mount as final crew selections go forward for a special observation flight of the sun. At the core of the conflict is the potential for one of the crew to be a woman. The other candidates fail to treat her as a highly trained crew person and only see her as a vulnerable woman. Ultimately she uses her gender to solve the problem

Col McCauley, while serving on the space station gets word his son has been seriously injured in a hit and run accident near the rocket base. Tension mounts as word comes through the driver of the car has been identified, and appears to be on duty on board the space station. With nowhere to run and nowhere to hide on the station, how will this terrible emotional conundrum be resolved?

While on a routine flight one of the rockets is hit by a meteor fragment. On Earth they run tests to discover the meteor is not only made of metal, but appears to have been artificially created. A second flight is launched immediately to retrieve more samples. What they discover may solve one of the greatest mysteries known to man.

A Moon survey mission finds a curiously-shaped rock formation. A month later, members of the return mission encounter other mysterious events and suspect that they are not alone.