Despite $1 trillion spent on enforcement and 2.5 million death toll, more illegal drugs are being produced, trafficked, and consumed than ever before. Featuring interviews and action filmed with key players on both sides of the law, this 10 part series will examine the drug wars - both past and present - to explain why.

How a group of marijuana traffickers created Mexico’s first-ever drug Cartel and committed murder to protect their billion-dollar operations.

El Chapo Guzman’s rise to cartel leader through his ingenious cocaine-smuggling tunnels and a war with the Tijuana cartel unleashes narco terror.

Pablo Escobar goes from cocaine tycoon in the late ‘70s to full-blown narcoterrorism by 1985, waging war against the Colombian state.

Pablo Escobar goes to war against both authorities and his rivals, the Cali cartel, as his terror sees airliners blown up and politicians assassinated.

One drug lord uses millions of drug dollars to bribe soldiers to desert the army to form The Zetas, the most feared cartel in Mexico’s history.

Upon Escobar’s death, the Rodriguez brothers take over as the new cocaine kings, specializing in corruption and buying Colombia’s presidents.

Meth kingpin Nazario Moreno turns a drug cartel into Mexico’s first narco cult: the gruesome Knights Templars.

The search for the world's most-wanted drug trafficker - El Chapo - as told by two women in Chicago whose drug-dealing husbands turned against the man who supplied nearly half of America's narcotics and the key DEA agents who finally brought him to justice.

In the mid-1990s, left-wing guerrillas and far-right paramilitaries plunge Colombia into a civil war financed by the profits from cocaine trafficking

Carmine Galante was the mafia boss who industrialized heroin smuggling into the United States. A brutal psychopath, he let nothing stand in his way…

The rise and fall of Philadelphia mobster Long John Martorano, who built a meth empire worth $500 million; told for the first time by those closest to him.

In 1980s New York, John Gotti kills the boss of the Gambino Crime Family to protect his drugs empire, breaking the Mafia’s most sacred rules and becoming the infamous ‘Teflon Don'.

Sammy The Bull attempts to go straight in Arizona, but gets sucked into a major ecstasy-dealing ring after his kids get a taste for raving.

Henry Hill was just a low-level Mob associate. But his 1980 arrest for drug dealing brings about the downfall of the Mafia’s wealthiest crew…

The Rizzutos were one of the longest ruling dynasties in Mafia history. They built a multibillion dollar cocaine empire that spanned two continents.

In this enhanced episode, an army veteran helps flood Harlem with heroin.

Drug lord Khun Sa floods New York, N.Y., with purity heroin until the DEA hatches a plan.

The mob connects with the Mujahideen to create an ambitious heroin pipeline.

DEA agent Jeff Higgins sets out to avenge 9/11 by taking on an Afghan heroin kingpin and proving the close link between narcotics and terrorism.

Party bro and convicted felon Chris George floods the U.S. with addictive pain medication, until the FBI hatch a plan.

How rogue chemists and street gangs brought fentanyl to America - and the vicious Mexican cartel that controls this deadly opioid today - the CJNG