With the drug trade out of control in Las Vegas Lt. Farlowe convinces the brass that it is time for new methods with a different breed of cops. He pulls together the wildest and best of the Vegas force to form a super-secret strike force, he calls the North Town Narcotics Bureau, dubbed The Nasty Boys by local press. The Nasty Boys begin taking the drug dealers rings apart apiece at a time. Payday, the leader of one of the drug gangs, is not willing to simply wait and let the Boys come to him. He takes his fight to them head on, leaving Lt. Farlowe dead.

Cruz goes undercover to infilitrate a deadly poker game run by a maniacal drug lord, leaving Lt. Krieger to watch over Serena when she goes into labor.

Illegal automatic weapons are hitting the streets of California and Vegas is the funnel. It's up to the Boys to stem the flow before the streets of Cali run with blood. Each of the Boys begins tackling the problem using their own talents and snitches. Wheeler goes undercover as a dancer in a casino in order to get close to a woman involved in the weapon sales. Wheeler is in over his head when he falls for his target and has to kill her brother.

The Boys take a trip to LA to bring down an Australian drug ring. Lt. Franklin makes a comment about trying to loose weight when offered a piece of Connie's birthday cake. In retaliation to the Boys trip to LA Serena Cruz and her child, Connie, are terrorized with Connie kidnapped as a bargaining chip. In protective custody for Cruz's family is put under strain. Cruz tries to make a deal with Australian drug ring, an exchange, Connie for members of the ring in federal custody. Cruz spills the beans to the rest of the Boys who set a dangerous plan in motion to get Connie back. It fails and Cruz's marriage reaches the breaking point. Cruz breaks with the Nasty Boys vowing to get Connie back his way. Krieger forces an old undercover associate to find Connie whatever the cost.

The man running for governor is gun down just days before the election as he declared an all-out waragainst crime. The Nasty boys move into a new hide out. The would-be Lt. Governor throws his hat in the ring saying he will pick up where his friend left off. His supports of the Nasty Boys boost his approval ratings and the current Governor who is anti-Nasty begins to suffer. Wanting to see what a day in the life of a Nasty Boy is like the politician takes a ride with Wheeler and Larson he shots dead the assassin. The ensuing IA probe could prove to be the end of the Nasty Boys. Larson's father drops a bombshell that the Governor-to-be is dirty. Krieger and the Boys begin digging only to find Larson's father was right. Bribery, extortion, and election fraud are in this guys closet. It's up to the Nasty Boys to punch his ticket.

The Boys are given Federal Marshall status and off to LA, once again. This time Wheeler's undercover as a cop, Cruz and Kee as drug dealers, and Morrisey and Larson as a couple of drug running bikers. Who's the target of such a wide sting? The LAPD Narcotics Unit. With three detectives, a LT., and a Capt. stealing from drug dealers, keeping the money, and selling the dope Wheeler has got himself in deep. When the dust settles four cops are dead and the LAPD in shame. Will Wheeler cross the line to avenge the death of an innocent cop?

A gang war erupts between the Asian gangs in LA. Kee is called home by is mother for the funeral of his other uncle. As it turns out his uncle is the leader of one of the competing gangs. Kee's cousin runs a dojo as a way to stay out of the gangs. Krieger thinks Kee could use some help and sends The Boys as back up. Kee's uncle drops a bombshell on him when he decides Kee should now lead the family gang. The war begins to heat up as the Boys arrive on their unauthorized assignment to take down Kee's uncle.

Serena's mother falls ill so she is off to the hospital with Connie in tow. Cruz on assignment is unable to watch the baby so is up to the Boys. An old Nemesis of Krieger is getting under his skin. The Boys raid his house and confiscate a stash of expensive basketball tickets. Wheeler's cousin is feeling the pressures collage basketball from the bookies, school, and the league. Wheeler's cousin on his first try OD's on crack. With A high profile basketball player dead the Boys kick it into overdrive to bring down a corrupt sports agent.

Wheeler's snitch Moe, who runs a helicopter service, has came across a major drug labor in the dessert. The word is that a large shipment is going out and the lab is to be shut down and moved. In the rush to get to the lab neither Krieger or Larson can be reached, leaving the team short two. When the short-handed team finds the drug lab the are out numbered 3 to 1 and severely outgunned. It's a running firefight across the dessert for nearly a day when the Boys are corned and captured. BY them Krieger and Larson have begun a search for their missing comrades. Their search leads them to Moe who is not telling that he abandoned the Boys is the dessert. Faced with a grizzly execution the Boys desperately try to free themselves.

Drug dealers are being killed by a vigilante. With a personality profile the Boys begin a door to door search for the killer. Larson begins to doubt the team's effectiveness while he attempts to get a gang-banger out of the life with out blowing his cover. Taking a leap of faith Larson breaks his cover in a act of faith to the gangster. On his own Larson goes after the vigilante, almost getting himself trapped. In a last ditch effort to get the vigilante Larson and the gang-banger put themselves in the snipers crosshairs. The trap works but the courts kick the sniper loose, who takes his revenge by killing the reformed gang-banger. He then takes Cruz and a drug dealer hostage threatening to blow them al up unless he get air time on TV and to perform a trail against the dealers and the cops.

Drug dealers are being killed by a vigilante. With a personality profile the Boys begin a door to door search for the killer. Larson begins to doubt the team's effectiveness while he attempts to get a gang-banger out of the life with out blowing his cover. Taking a leap of faith Larson breaks his cover in a act of faith to the gangster. On his own Larson goes after the vigilante, almost getting himself trapped. In a last ditch effort to get the vigilante Larson and the gang-banger put themselves in the snipers crosshairs. The trap works but the courts kick the sniper loose, who takes his revenge by killing the reformed gang-banger. He then takes Cruz and a drug dealer hostage threatening to blow them al up unless he get air time on TV and to perform a trail against the dealers and the cops.

A group disguised as the Boys hits a crack house leaving ten bodies in the wake and the Nasty boys locked in the sights of Internal Affairs. With the police brass breathing down his neck Krieger refuses to divulge the names of the Nasty Boys. It is not long before the mastermind behind the Nasty Boy's problems is revealed as an old enemy, Payday, last seen in the pilot movie. Payday killed the Boys first leader and now the Boys are out for a little payback.

The Boys fear being shut down with the lose of Capt. As it turns out despite some negative aspects of the Nasty Boys the police Brass can not argue with their results. The brass sends out a new team leader, Lt. Krieger, who is drastically different leadership methods that class with some of the Nasty Boys.