After a Marine's wife is kidnapped for ransom, the NCIS team uncovers dark secrets as they race to track down her abductor before it's too late. Meanwhile, Sam seeks Ernie's expertise decrypting a computer program that may have deadly ramifications.

When a high-value bioweapons expert is murdered in a secure facility on Hawai'i, NCIS and the NCIS Elite team join forces to track down the killer and discover an even deadlier threat.

Following a devastating ambush with a deadly bioweapon, the NCIS team must track down a mysterious terrorist group before they can strike again.

The NCIS team investigates the death of a Navy sailor and goes head-to-head with a ruthless local criminal organization. Also, Lucy looks for a new apartment.

When a Marine corporal dies in a tide pool after being exposed to fentanyl, the NCIS team must quickly find the source of the drugs; Alex talks to his parents about taking a gap year; Ernie reveals personal news to Lucy.

When Commander Chase is abducted from her home by an Army Ranger accused of murder, the NCIS team must act quickly to find her and the suspect.

An experimental Naval aircraft crashes on Oahu, and Tennant and her team must find who is behind it before classified state secrets are exposed.

The NCIS team's investigation takes them deep into the world of illegal street racing after a Marine staff sergeant's body is discovered in a junkyard. Also, Tennant is concerned Alex is hiding something from her, and Whistler is anxious about introducing Lucy to her co-workers.

When Navy residents discover their vehicles were burglarized overnight, the NCIS team connects it to a series of peculiar crimes and tracks down an unlikely bandit. Also, Whistler struggles with an uncooperative CI and Alex weighs his college options.

Following the crash of a prisoner transport plane, the NCIS team must find the convicts that escaped onto the island. Meanwhile, Sam Hanna and Tennant are tasked with locating a high-profile Russian prisoner known as "The Chemist".

After a brazen daytime robbery of a Navy Federal Credit Union, the NCIS team tracks down a group of adrenaline-seeking thieves. Meanwhile, Tennant grows suspicious of Sam Hanna's reasons for being in Hawai'i.

When evidence to put away a drug kingpin is stolen, Lucy goes undercover at an underground poker tournament to find out which high-roller is behind the crime. Also, Lucy’s feelings are in turmoil when Whistler’s ex-girlfriend arrives in town.

After Tennant passes her medical and psych evaluations, she's surprised to see Sam's conducting her final interview to clear her return to work. Also, when the team discovers a breach in the U.S. Marshal's database, Sam joins Tennant in Las Vegas to locate the hacker.

Kai goes undercover with one of Hawai'i’s oldest surf gangs when a petty officer who’s trying to help wayward kids find a new path in the Marines is murdered.

Tennant, Jimmy Palmer and Sam Hanna find themselves captured with a woman who claims to be a CIA agent demanding intel from the team. Also, Jesse, Ernie, Whistler and Alden Parker learn about an asset that arrived in Hawai’i who could be connected to several overseas assassinations. The crossover starts on NCIS S20E10 Too Many Cooks (I). It continues on NCIS: Los Angeles S14E10 A Long Time Coming (III).

When Special Agent Pike is ambushed while working undercover with a local Japanese crime family, the team must find the person responsible for orchestrating the attacks. Also, Kai goes deeper into his investigation regarding an old friend turned criminal.

When an elite special forces Marine captain is murdered, the NCIS team finds a suspect in a really unusual place.

When the murder of a captain and his wife echoes a previous case, the NCIS team brings in a former team member to help determine if they are dealing with a copycat killer.

When a marine is shot, the team investigates. They start by talking to him, he tells them that he went riding and he got shot probably by a hunter. They check out his story and learn he wasn't telling the truth. They go back to see him but he left the hospital, not fully healed. They learn a relative came and helped him. They see the relative, who doesn't know much but they find a bag filled with drugs. They think the bag belongs to his son. So they try to talk to him but he disappeared. They think the boy was asked by a drug ring to deliver the drugs but he changed his mind which means his father is trying to protect him. But the gang will stop at nothing to get them, so they try to find them. When Kai's father doesn't see his doctor, Kai needs to put aside his feelings to help his father.

When a Japanese sailor is killed on American soil and evidence links the case to the previous murder of the victim’s girlfriend back in Japan, NCIS must find the murderer before the wrong person is accused and the case triggers a diplomatic crisis.

When Tennant and NCIS are tasked with finding a kidnapped globe-trotting social media star, they find that she is not who her husband, or her followers, think she is. Also, the team is at odds with Whistler, who has an agenda of her own.

When a Navy petty officer is murdered, Jane and the team investigate while protecting the victim’s friend and colleague.

When an anti-capitalist protestor is murdered, Jane and the team investigate and find themselves caught in a war between eco-activists and a tech billionaire fighting over a piece of land. Also, Jane and Captain Joe go on a date.

NCIS crosses paths with Whistler's team while investigating a shipping container filled with contraband weapons; Tennant debates arresting Alex's friend's dad, knowing it will cause her friend to move away.

Kai goes undercover as a chef in a local restaurant to gather intel on a notorious criminal kingpin who has a connection to the eatery. Also, Jane discovers that a school on the mainland has recruited Alex on a baseball scholarship, which he's kept secret from his family.