Follow Nishant, Sakshi and Huma, first year MBBS students, as they navigate the first few weeks of college and meet quirky, unique people. An incident in the dissection hall ends with Nishant figuring out how to apologize to the two girls.

A month into the first year of MBBS, Nishant, Huma and Sakshi balance an infinite syllabus, difficult practicals and the desire to actually enjoy their college life. But as their party comes to an abrupt end, they learn something about Nishant which changes their perception of him.

Mid term results are in for our students and they're in for a surprise. As they celebrate their results, they realize that there's something much deeper at play which they need to address.

As Huma struggles to gain back the confidence she's lost, Rukmini gives her a tricky solution. Meanwhile, as the three hold on to their resentments against each other, a heartbreaking event forces them to reconsider what it is that really matters to them.

Huma, Nishant and Sakshi gear up for their final exams. As Huma considers whether to cheat or not, the others learn something about her which irreversibly changes her image.

The second year of MBBS is known to medical students as the honeymoon period before things begin to get really tough. But as our trio settle into this new phase, they realise they’ll have to dig deeper than they expected, especially with one particular case of coronavirus taking a personal toll on all their lives later on!

ABJMC is turned into a COVID hospital and the entire medical staff is debriefed on the upcoming protocol. Tracking back a few months, we see Sakshi learn some truths she wished she hadn’t while both Nishant and Huma find help from unexpected sources.

With hospitals running out of beds, the atmosphere threatens to get violent. The Dean must step up and find a solution. As we track back a few months, semester exams are back. However, our students aren’t as prepared as they thought they were.

Yash realises a tough lesson as he's faced with the toughest challenge of his medical career. Meanwhile, everyone's dealing with the first challenges of the lockdown, as Sakshi finds out a truth about the Dean she never expected.

In the Season Finale of Operation MBBS, our students tackle the final days of their lockdown within the college. With a massive shortage of supplies, the Dean rallies her troops and finds a solution through an unlikely source.