Baek Beom, a medical examiner, performs an autopsy on a young victim. Cha Soo Ho, a detective, watches the procedure from behind a glass. He mentions the disappearance of the victim’s underwear and skirt and tells Beom that the victim was raped and murdered. However, after a short while of examination, Beom tells him that it is a car accident disguised as rape and provides medical evidence.

All the evidence that they find point toward Soo Ho. Although he cannot re-member much from the night before, he implores that he did not kill Yeon Mi Rae. Due to Sol’s relationship with Soo Ho, Kang Hyun is appointed as the lead prosecutor for the case, and Sol is only allowed to work with him. Although she cannot find any sturdy evidence that can help Soo Ho, she feels it in her stomach that he is not the murderer.

A female victim is taken to the hospital with seven stab wounds on her body. She says that her boss tried to kill her, however, the suspect denies all the charges against him. Prosecutor Eun Sol is in charge of the case, and at the trial, she encounters Doctor Baek Beom who comes to the court to provide his expert opinion on the stab wounds.

As soon as they thought they get some rest after solving a case, another murder occurs. The scene of the murder is rather clean, but the body is mutilated and burned. Both the NFS and prosecution rush over to collect evidence and figure out what happened.

Eun Sol continues to find more evidence related to the case and visits the female victim’s house. Meanwhile, two members of a gang are found dead, and Baek Beom is asked to perform autopsies on them. In the middle of the autopsy, unexpected guests visit Baek Beom and his colleagues.

Everyone believed Cha Joo Hee died in a car accident, but according to Baek Beom’s opinion, her accidental death is now a homicide. And based on a chemical substance found in the female victim’s body, the female victim’s sister Cha Do Hee is now the prime suspect.

The prosecution and the NFS keep working on finding out the real culprit who killed Cha Joo Hee and made it look like an accidental death. They continue to follow the evidence and end up suspecting more than two people as suspects.

A married couple dies in two different car accidents almost at the same time. After their death, the bereaved families of the husband and the wife starts to fight over the inheritance. In order to find out the time of death of the two people, Baek Beom and Do Nam perform autopsies on them.

The prosecution and the NFS continue to work hard to find out the truth behind the couple’s death. Through security camera footage and a background check on Cha Do Hee, the female victim’s sister, Eun Sol realizes that Cha Do Hee has fabricated the time of death of her sister.

As if one body wasn’t enough, they find a second victim. The body and the murder scene, however, are too similar to the first victim. The prosecution thinks this is a spree killing case and mobilizes the police to search and apprehend the culprit. Meanwhile, The NFS conducts autopsies on the two bodies.

Ji Han finds Hee Joo's tablet and starts investigating further. He, however, gets criticized for not being present at the crime scene with the newly discovered body parts. Meanwhile, the autopsy for the two victims take too long, and the result is inconclusive.

Eun Sol, a newbie prosecutor, holds hands with Baek Beom and Cha Soo Ho to investigate a murder case of a conglomerate’s son’s wife. Sol and Beom specu-lates that the husband beat her, who was pregnant, to death. However, Beom tells her never to trust the corpse itself because once a body decomposes, new scars may show up, and existing wounds may vanish.

Although the trial seems to be leaning in the defendant’s favor, Sol does not lose heart and begs Beom to analyze the heels that she wore to the crime sce-ne. The results show that on the carpet where Hee Kyung was found, traces of pills are found. Sol immediately believes that Man Sang has replaced the con-tents of Hee Kyung’s pills into those that would kill her.

Sol goes on her 99th blind date and is not impressed with the low self-esteemed mama’s boy. To his mother who has been watching them the entire date and has handed her three million dollars in order to convince her to marry him, Sol tells her that her son should learn how to grow his self-esteem and figure out his own life. Meanwhile, Deuk Nam’s three sisters find out that their brother’s body is missing and goes berserk.

Suspecting the late Jang Deuk Nam’s death to be a murder case, Sol indicts his three sisters and his wife, Choi Hwa Ja, for murder. Meanwhile, while talking with Kang Hyun regarding the murder case, Hyun tells Sol not to trust Baek Beom too much. When she asks him whether there was a conflict between him and Beom, he just warns her to be careful.

All the wicked deeds that Choi Hwa Ja has done are revealed, and the dead body turns out not to be Jang Deuk Nam. In addition, Hwa Ja had a lover on the side, and the corpse belongs to that man. It is revealed that Hwa Ja murdered both of the men all because of the inheritance. Despite the result claiming that Hwa Ja’s kid is actually Deuk Nam’s and not her lover’s, Sol requests a heavy verdict.

Prosecutor Do Ji Han firmly believes that the killer is the same killer from 30 years ago, and therefore, is a serial killer. Realizing the graveness of the situa-tion, a new team is formed solely for this case, and Pyo Yoo Seong takes the lead. Although Sol repeatedly tells Ji Han that they cannot ignore the possibility of a copycat, Ji Han refuses to listen.

Eun Sol is shocked to see Baek Beom stand as a witness for the conglomerate son, Oh Man Sang. Beom testifies that the cause of Kwon Hee Kyung’s death is not assault. Meanwhile, due to the lack of evidence, the trial is postponed for three days. Will Sol be able to find more evidence to prove that Man Sang is the killer, or will Man Sang be set free?

Baek Beom finds Choi Hwa Ja’s fingerprints on the dead Byun Soo Kyung’s blouse. He immediately calls Kang Dong Sik to ask where Eun Sol is, only to find out that she has left to meet Hwa Ja. Frantically, Beom calls Sol’s phone. Meanwhile, after waving to Sol and telling her to come in, Hwa Ja mixes an un-known substance in Sol’s drink.

Soo Ho’s shoe is found at the house of Yeon Mi Rae, who has been found dead. Sol and Dong Sik immediately go to his place to find him reeking of alco-hol. Soo Ho is taken to the police station as a suspect. When Dong Sik asks him what happened last night, Soo Ho tells him that he cannot remember.

This time, Sol and Beom are faced with a car accident case. The driver of the car, Choi Mi Jin, has died at the scene of the accident while her boyfriend, Jeong Ji Hoon, came out unscathed. While performing Mi Jin’s autopsy, Beom finds it odd and tells Sol that Mi Jin was not behind the wheels from the beginning.

While helping Beom with the autopsy of a man suspected of MERS, Sol feels faint and gets her palm cut by a scalpel. Not being able to get any help from an-yone outside due to being quarantined, Beom stitches her palm himself. Hyun rushes over to the autopsy room and becomes enraged by what has happened to her.

Ma Do Nam becomes enraged when he hears that his late son, Sung Jae, has probably committed suicide. He shouts at Beom, telling him that his son would never do something like that. However, the autopsy result shows that Sung Jae has committed suicide approximately four hours after eating, which is around the time he was alone.

Eun Sol arrives too late and finds the body already in the process of cremation. However, Beom tells Hyun that if he can obtain even one piece of the bone, the autopsy can be performed. Hyun, who’s hesitant at first, orders the body to be brought to the NFS. Dong Sik doesn’t understand why Beom is so determined to prove that it’s a homicide since that will only make Beom himself suspicious.

Lee Kyung Ja, a past victim and survivor of the Wuseong Serial Murder case, is found dead. Pyo Yoo Seong leads the autopsy himself while Beom grudgingly obliges to be his assistant. During the autopsy, Beom smells something odd and starts sniffing around. Meanwhile, news reporters ask Do Ji Han if he is to blame for the death of Kyung Ja.