Gus Huffle, the owner of the Pixley Bijou movie theater, has decided to close due to lack of business. Sam says that a big part of the problem is that Richard Arlen and Charles 'Buddy' Rogers, who were supposed to come to the Bijou for the world premiere of their Academy Award-winning Wings (1927 film), decided instead to attend a premiere at the Roxy in New York City. Joe decides to write a nasty letter to Arlen and Rogers. After receiving the letter, Arlen and Rogers think that attending a world premiere of the movie at the Pixley Bijou - despite being forty years late - would be good publicity. When they arrive in Hooterville, the community pulls out all the stops, including a parade and musical performances.

Norman Curtis, who has fallen in love with life at the Shady Rest, is still staying there for free without Kate yet knowing his true identity. He accidentally breaks the throttle handle of the Hooterville Cannonball and folks can't get to Kate's annual Shady Rest Jamboree. Norman decides to come clean about his identity. The problem is no one believes him. In fact, they all believe he's crazy. But the executive tries to make amends with a determined effort to obtain the nearly-nonexistent replacement part. Norman brings three of his friends in to help, who everyone also think are hobos. Thanks to Norman, the Jamboree is a success.

Kate receives a telegram from Railroad President Norman Curtis that he is sending Homer Bedloe with someone named Fred. Fred is actually Mr. Curtis' housekeeper's aged basset hound. Curtis believes Fred needs some good country air and space to re-energize himself. Curtis also hopes that Bedloe will soften his ways in the process. Bedloe comes up with the plan to "ruin" Fred and have him return to Curtis in worse shape than he arrived. That will hopefully sour Curtis' view of the Shady Rest and what it stands for. Kate figures out a way to bring back spirit to Fred and a way to break Bedloe's spirit.

Jealousy will permeate the Shady Rest Hotel. After he agrees to go to the turnabout dance with Bobbie Jo, Tommy Johnson has to back out due to another commitment. As Billie Jo and Steve recently had a fight and Billie Jo isn't speaking to him anymore, Bobbie Jo feels that Steve is fair game. Steve accepts Bobbie Jo's invitation. Tommy tells Bobbie Jo that he now can make it to the dance since the other commitment is no more. Since she already has a date with Steve, she now refuses Tommy. Feeling Tommy is now fair game, Betty Jo wants to ask him to the dance. Tommy says yes to Betty Jo's invitation. The problem with these pairings is that the girls are now jealous about each others boyfriends. Add to the mix Jerry Massett, a mechanic friend of Steve's from his air force days, who is visiting Hooterville. Jerry ends up asking a free Billie Jo to the dance, which makes Steve jealous. A storm helps the girls get together with their proper boyfriends.

C&F W Railroad President Norman P. Curtis is incensed that ace troubleshooter Homer Bedloe utterly failed to scrap the Hooterville Cannonball. Taking matters into his own hands, he decides to do it himself, incognito. Although Curtis doesn't intend on appearing as such, he comes across to Kate and others in the valley as a hobo after he takes a tumble in a field, ripping and dirtying his suit and losing his wallet in the process. But, he has a change of heart when he experiences Kate's hospitality and kindness.

Norman Curtis, President of the C&FW Railroad, is currently on vacation in Europe. He left instructions not to do anything to the Cannonball while he's gone. However, Homer Bedloe has a scheme to shut down the Cannonball for good. He hopes to do it without disobeying Curtis' orders. The plan entails Bedloe being appointed Superintendent of the Cannonball. He would then enforce an efficiency program with an impossible to meet new schedule. He expects Charley and Floyd will eventually just give up. Kate and the gang go to the stockholders meeting where she believes they've got a secret weapon to ruin Bedloe's plans.

There's a dance on Saturday. Billie Jo and Bobbie Jo will only accept a date from either Steve or Don, the new young doctor in the valley. Neither Steve or Don have asked anyone to the dance yet. Billie Jo believes she has the right of first choice being the oldest. Left out is Betty Jo, who feels she has the right to be included in the dating discussion. Not wanting to take it anymore, Betty Jo decides to strike out on her own by moving out and getting a job. Through a series of misunderstandings, Billie Jo and Bobbie Jo wind up going to the dance with Eb and Betty Jo shows up with Steve and Don. It's not long before the girls are paired off with the boys they should've been with all along.

Baby Kathy Jo almost misses her ffirst birthday party when she lands in jail with Uncle Joe.

Homer Bedloe, trouble-shooter for the C&F W Railroad, is sent by railroad president Norman P. Curtis to the little community of Hooterville to find out why a branch line doesn't connect with the main line. The branch line carries the "Cannonball" train, and is vital to the Shady Rest Hotel, run by Kate Bradley, her three grown daughters and "Uncle Joe" Carson. If Bedloe succeeds in shutting down the Cannonball, Kate faces ruin. John Ashley appears as passenger Fred.

The Bradleys, Sam Drucker, Herby, Charlie and Floyd are decorating the Cannonball for its annual Christmas Eve trip of caroling, gift-giving and merriment around the valley. But, Homer Bedloe is determined to be a Scrooge and take possession of the train on Christmas Eve. Railroad President Norman Curtis finds out what Bedloe is up to and goes to Hooterville to stop him.

Kate's first boyfriend, Walter O'Connor, who is now a major league baseball manager, is coming to stay at the Shady Rest. While Kate is excited to see Walter, she is still just as anxious and nervous about him actually asking her to marry him. Regardless of Walter's intentions, his being there makes Sam come to the realization that he too has feelings for Kate. Walter proposes to Kate, but she turns him down.

Kate uses a combination of charm, subterfuge, and wiles to prevent Homer Bedloe from catching the Hooterville Cannonball and getting to Pixley in order to initiate proceedings that would permanently terminate the train's operation. She has to keep him at the Shady Rest long enough to convince him that the Cannonball is an integral part of the valley's life. When all else fails, Kate gets Sam, the Hooterville Jack of all professions, to scare Bedloe into changing his mind.

The Cannonball and its primary passenger, Uncle Joe, are pelted with eggs after the Hooterville Hornets, coached by Uncle Joe, are drubbed in what may be their worst game ever. Another unexpected passenger on that run is Homer Bedloe, who is surprisingly cordial and pleasant. Uncle Joe doesn't see anything wrong with Bedloe being cordial and taking it like a man in defeat in his efforts to scrap the Cannonball. Kate on the other hand believes Bedloe is up to no good. News gets to Sam that John Fisher and Max Thornton, two bigwigs from the railroad, are coming for a surprise inspection the following day. When Kate learns this news, they have to go clean-up the Cannonball. Plus, they have to keep Bedloe preoccupied so that he won't know what they're up to. And third, they have to railroad the visiting bigwigs about how deluxe the service on the Cannonball is. Fisher and Thornton are very impressed with the service.

A brochure made by Uncle Joe describing the incomparable Shady Rest Hotel of the future is accidentally mailed to The Centerville Sun Express travel columnist Gladys Stroud. In the brochure was the vision of what he hoped the hotel would one day be, including indoor ice rink, bowling alley, and swimming pool. Gladys decides to come and review the Shady Rest. Now the family has to scramble to keep her from finding out the truth and closing them down for lying. Despite their best efforts, Gladys finds out. Uncle Joe manages to sweet talk Gladys into not closing them down.

Business is bad at the Shady Rest and Kate needs to make a $200 bank loan payment. Uncle Joe meets Henrietta Boswell and Gertrude Hawley, who are lost and looking for Madame Bovary's Hideaway Reducing Farm. He convinces them that the Shady Rest is the most exclusive reducing farm and charges them $200 for a week. The catch is that Uncle Joe provides them with a money back guarantee. Uncle Joe tries to hide from Kate why the women are staying at the hotel. With a rigged scale, Joe has to convince the two that the secret to weight loss is to eat whatever they want as long as it is combined with turnip greens. He also has them do what would normally be considered all his chores. Ultimately, the two women do whatever they can to find what they believe is Kate's miracle weight loss and youth secret.

Kate's former grade school teacher returns to Hooterville. Kate and her children reminisce how Miss Adelaide "Genghis" Keane was so strict on all the children, and she was a dreaded teacher. Kate and the girls are surprised to find that the elderly schoolteacher is no longer the tyrannical disciplinarian she used to be. They all get together to bring Miss Keane's confidence back. It doesn't take long for Miss Keane to become a disciplinarian again and Kate and the girls are beginning to regret what they did. Before Kate can confront her, Adelaide acknowledges that she has gone too far and is scaring people off. Kate finds a way for Miss Keane to be happy again.

It's the Christmas season, and everyone's in a rush to decorate the Cannonball in preparation for their annual caroling and gift delivery runs. Their plans are placed into jeopardy with the arrival of Homer Bedloe. He says that what they are doing is against railroad policy and he won't allow it. Kate hopes that Bedloe will have some heart, and she tries to use her best Christmas spirit in treating Bedloe with kindness to change his mind. Only Norman Curtis, the President of the Railroad, may be able to make Bedloe change his mind.

Uncle Joe spends Kate's money to buy cases of lousy smelling men and women's cologne to make a fast buck reselling it. The money was intended to put screens in the hotel that will keep mosquitoes from chasing away paying guests. Kate figures out a way to sell all the cologne to salesmen Mr. Blake and Mr. Gordon. The men are going to sell it as insecticide.

Two young men, Arthur Gilroy and Lowell Rightmeyer, are on their way to rob the bank in Pixley. They change their plans when they learn that the next day, the Cannonball, without any armed guards, will make its run from Hooterville to Pixley for the bank shipment. Arthur and Lowell decide to stay the night at the Shady Rest. Kate and the family are happy to have two polite and handsome young men stay with them. Arthur and Lowell do hold up the train the next day. But, Kate and Uncle Joe are also on the train and they recognize the masked bandits. When Arthur and Lowell learn that the bank shipment is only deposit slips, they decide to rob the Shady Rest instead. But will Kate, her family, Charley and Floyd be able to turn around Arthur and Lowell's criminal lives?

Beatlemania has hit Hooterville by storm. Uncle Joe recruits Billy, Bobbie, and Betty Joe along with their friend Sally Ragsdale to form their own band called the Ladybugs. Colonel Partridge, a booking agent, comes to the Shady Rest to see the girls in action. Partridge likes what he hears and wants to book the girls. Sally's father, Sheriff Ragsdale, comes by and says he wants his daughter to finish school and not tour the country. Uncle Joe thinks he has a way to save the group and dresses up as a Ladybug.

Uncle Joe gets angry at Charlie and Floyd when he is left behind by the Cannonball. He decides to start his own transport business by using Orville Miggs' "Flivverball", an old car converted into a railway car. At first the Flivverball is a success. Kate must now deal with the feuding groups before the Cannonball goes out of business.

While the girls are swimming in the water tower, a bi-plane flies overhead. The pilot, distracted by the beautiful girls he sees in the water tower, crashes the plane by the railroad tracks next to the hotel. The family manage to get the unconscious injured pilot up to the hotel. For all three girls, it's love at first sight. Each of the girls do whatever they can to gain Steve's favor while they nurse him back to health. Steve will do whatever he can to stay at the hotel as long as possible. Kate and the girls later learn that he is a crop duster. Uncle Joe believes Steve's a Russian spy. Steve tries to use Uncle Joe's belief to his advantage.

Kate Bradley tangles with Selma Plout when Selma tries to lure pilot Steve Elliott into marriage with her daughter, Henrietta. Selma tries to throw both money into Steve's crop dusting business and gourmet meals to entice Steve. Selma ramps up her fight one notch by moving herself and Henrietta into the hotel to be closer to Steve. Kate, knowing Billie Jo and Steve are officially dating, comes up with a plan. She enlists the help of Floyd and Charley to get Selma uninterested in Steve.

A crew is filming a commercial at Lost Lake. The commercial stars Prince Hamlet of Kronenberg von Auschwile III, a rather large and imposing but valuable dog. Mr. Morton, the film crew director, needs Steve to fly him immediately to make a connection to a flight to New York. Hamlet can't risk the flight in Steve's plane, so he has to stay at the Shady Rest under the care of Uncle Joe. With all the special treatment Uncle Joe and the girls give Hamlet, Dog feels like the forgotten family member. So, Dog runs off. Uncle Joe makes Hamlet track Dog's scent, but Hamlet gets away. Everyone comes to realization who is really the valuable dog, when Dog finds Hamlet.

Steve has been spending a lot of time with Betty Jo. He's giving her flying lessons and she's his grease monkey in the airplane's repairs and maintenance. Billie Jo becomes jealous of her younger sister. Billie Jo tries to be more like Betty Jo and be a grease monkey for Steve. While Betty Jo tries to act more grown up in an effort to be seen in a more feminine light. Neither Billie Jo or Betty Jo achieve what they wanted. Betty Jo in particular feels let down as she wanted to feel like a threat to Billie Jo. After Steve's attempts to make it up to Betty Jo while letting her down easily fail, Betty Jo decides to take drastic measures to get what she wants.