Big Nose wants to spend his day with quiet hobbies like assembling his ship in a bottle, stamp collecting, and pottery, but neighbor Pink Panther makes the task difficult as he plays various music instruments in his garage. Even calling the police won't help as they manage to join Pinky to form a band. As a last resort, Big Nose takes his dog with him to the furthest, most isolated cabin he can think of. But even that doesn't work since his dog enjoys music and manages to get the stuffed animals in the cabin animated enough to join him in a jam session as well.

Aardvark is out of shape and finds himself too worn out to chase Ant. He returns to his cave where he develops various energy drinks to give him the necessary boost to chase Ant in the jungle. However, increased speed, laser vision, powerful nostril suction, and even boosted intelligence aren't enough to get the better of the crafty Ant. Aardvark actually catches him the old fashion way.

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Pink Panther wants the latest pair of hi-top sneakers that everyone has. A golden pair that seem to have a life of their own come along and get on his feet, causing him to zoom all over the world at fast speeds. He makes it back to the city, but has trouble removing the sneakers until he finds himself on a jetliner. The hi-tops eventually come off his feet, but when Big Nose is walking his dog, he puts them on and gets carried off the same way.

After Aardvark unwittingly gets into a tiff with Eli the Elephant, the pachyderm drops him into a prehistoric subterranean world where aardvarks are significantly smaller than primitive ants. Modern day Aardvark tries to train his prehistoric counterpart on how to catch a giant ant, but their efforts are unsuccessful. Aardvark then gets into a tiff with a wooly mammoth, who knocks him back home to the jungle, before Eli drops him back down to the prehistoric world.

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Pink Panther takes over Big Nose's magic show, drawing a big crowd and applause, leaving the disgruntled magician to try to get back on stage to win back the crowd. His efforts are unsuccessful and Pinky only becomes more of a hit, leaving Big Nose frustrated as the audience carries Panther triumphantly out of the theater after his show is over.

Learning he can't resist parties, Aardvark invites Ant to his birthday party in hopes of making a meal out of him. But Ant is wise to his plan, inviting several of the other jungle animals to join them in what becomes a real party, impeding Aardvark's efforts.

Big Nose challenges Pink Panther to a game of miniature golf, then resorts to cheating in efforts to win. But his efforts backfire, especially when a rocket blasts him to the Moon. As a result, Pinky is the winner.

Pink Panther goes to the local arcade run by a stingy Big Nose, who does all he can to prevent the kids from getting prizes (A stuffed animal version off Horse.) by continuously increasing the number of tickets needed to win so to keep the toys all for himself. Pink finds this unfair and selfish and plays the various games, most against Big Nose himself in order to accumulate the tickets. The two then get literally get pulled into the video games where Pinky still comes out on top and stopping Big Nose in the process. Afterward, Pink Panther donates some of his tickets to a young boy and they make off with as many prizes as they can when they leave the arcade.

Ant and Aardvark are on exhibit at a zoo. Aardvark escapes his display in effort to get to the Ant's, but has a difficult time when he winds up going through other animal displays, then outside in the general public.

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Pink Panther gets a universal remote control for his entertainment system. However, it only works on various other items, like the vacuum, Big Noses's garage door, the sun and the moon. Other items in the house are changed and Pinky even finds himself altering his own cartoon. He eventually gives up trying to use it to operate his entertainment unit. But when he begins washing the dishes, he finds that the faucets can control the TV, so he brings it over to sit down and watch, then using the remote to fill his drinking glass.

Aardvark tries to catch Ant by using an invisibility spray, but his strategy doesn't work as well as expected, especially when Ant uses it to get the better of him. And things get worse when Aardvark insults a tiger and his mother, and goofs again when he accidentally uses the spray on them, enabling the two to wallop him good.

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Pink Panther goes to the local skate park only to find it closed for the day. But undeterred, he finds ways to drain the water from Big Nose's pool in order to use it as a substitute. But a battle ensues between them as Big Nose wants his pool filled so he can have a cool dip during the hot day.

A sloth offers Aardvark the chance to catch Ant by having him go high-tech in exchange for getting 50 percent of the meal. But efforts of using hypnosis, virtual boxing and portals all backfire, leading Aardvark to give the sloth 50 percent of the pummeling he received from the bear and the herd of elephants who denied him his desired meal.

Pink Panther tries to save the tree where he resides from Big Nose, who's in charge of building a highway. His efforts to cut it down are repeatedly thwarted until a last try seems successful, until the tree drops down on the new highway.

Pink Panther goes to the laundromat and his day is quite eventful, especially with Big Nose's family there. Pinky has to find an available washing machine, gets lots of coins from the change machine, then has to find an available dryer. And with kids using carts to race and spilled detergent, it becomes a major adventure. At the end Big Nose is piling all his clean laundry ready to leave only to have a passing truck splash mud all over the entire load, leaving him to stay at the laundromat longer to start all over again.

Aardvark catches a cold and while watching TV, sees an ad for a professional sniffing dog service. He hires one for 3 hours for the purpose of catching Ant, but the hunt doesn't go as well as expected. After spending his day photographing wildlife and the 3 hours are up, Ant hires the pooch to chase Aardvark.

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At their apartment building, Pink Panther and Big Nose are trying to bathe and shower at the same time. But there's not enough water for both apartments and the two battle to get their water at the right temperature. They continuously tinker with the building's plumbing, and eventually the reservoir by Big Nose, who causes geysers to pop up all over the city streets, leaving Pinky with more than enough water to shower.

Ant agrees to care for Mrs. Gorilla's baby while she's away for the day. Aardvark uses this as an opportunity to sneak up on Ant, but the baby gets the better of him each time. When mother returns, Ant agrees the baby can keep Aardvark as his new pet as he gets a jar of honey in exchange.

A narrator gives a documentary on the development and evolution of Primitive Man and Primitive Panther as they invent the wheel, various modes of transportation, ways of fishing, art, tools, and attempted flight.

Pinkaroni Pizza: Pink Panther craves pizza, but isn't able to find a parlor nearby. Instead, he buys the necessary ingredients to make one himself. He follows an audio guide on how to do so, which leads to funny results.