A terrorist cell infiltrates the NorBAC lab and forces the scientists to produce a deadly measles mutation to be used as chemical warfare.

Bob finally tracks down Nina, but on a visit back to Roth's lab he makes a gruesome discovery that suggests the experiment on Nina is about to go terribly wrong; the team investigates unusual crow attacks that appear to be targeting military airports.

David discovers that Roth has given the world's most powerful leaders the stem cell treatment that he now knows leads to violent paranoia; while investigating a mysterious outbreak in Moldova, Carlos uncovers a horrific act of atrocity.

Jill goes to Canada to see if the Spanish Flu body is still in the ground. David recovers from his coma and limps back to the office. Daisy recognises the person who created the Miranda virus and infected her baby. David identifies the vector for the Spanish Flu epidemic and tracks it with GPS.

Bob is back. His brain surgery caused an infection which leaves him in a bad shape when found. He is put into a medically-induced coma. The team travels to Mexico where an antibiotic-resistant strain of TB is killing the Zapatista Revolutionaries.

As if being HIV positive wasn't enough, Wes is infected accidentally with a needle full of Hepatitis C.

Bob continues to be haunted by memories of his time at Roth's secret lab; Wes insists that Rachel inject him with a highly experimental mutant red blood cells to fight the virulent Hep C; a mysterious disease that's causing brain inflammation in a small town appears to be contagious.

A pharmaceutical company comes under fire when its newly-marketed immune suppressing drug triggers a high incidence of congestive heart failure; David attempts to find a replacement for Wes; Bob suffers a seizure that triggers romantic memories of a girl named Nina.

David ignores protocol and hires his new lover, Enuka; Mayko is contacted by the parents of a sick child who believe she's the only one that can help.

Lilith befriends Mick, who is dying and desperate for David to help him discover if he really is a clone and possibly save his life. Meanwhile, NorBAC has managed to locate patient zero and must proceed with the interrogations at "Hazmat City." Was this an act of Bioterrism? Caroline is determined to find out who's responsible as more die and one more is exposed. David must now face his fate.

David and Jill make a trip to Colorado where a rampant SARS-like outbreak is occurring. David is in shock when he discovers that the outbreak is Spanish Flu, the virus he dug up in Nunavut. Racked with guilt, he walks into the path of a car and is sent to hospital in a coma before he tells anybody his fears. Mayko Tran heads to Colorado to try to find Patient Zero.

After a self-imposed exile to China, David Sandström is kidnapped by the People's Liberation Army and ordered to secretly investigate a deadly outbreak that has killed 19 people in a small village. With the help of three Chinese scientists, David discovers the outbreak has been caused by an ancient bacterium that has seeped into the village's water system. David is horrified when he learns that one of the scientists has decided to test the antidote on her self in order to expedite a cure. While David makes his way back to Canada, Caroline and Carlos are witness to a horrific attack at the site of the International AIDS Conference.

Carlos and David helped by a Cuban scientist called Eva Ramone look into a claim than an exiled Cuban is a victim of bio-terrorism. Bob being persuaded that Caroline's nephew, Glenn, is improving calls Simon Jessup to help him out.

David and Carlos are still investigating the poison that is affecting Charringa's lemon crops in Florida, before the United States decide to bomb Cuba. Jill, on the other hand, asks Mayko to contact all the other labs using the same stem cells from Korea to let them know a retrovirus is in that strain. Bob offers to verify all the steps one more time with her and see if her findings are correct. Simon Jessup finding that Glenn responds to all the stimuli suggests that he undergoes brain surgery.

Bob is trying to prevent a rain of concentrated sulfuric acid that would destroy Mexico City. Homeland Security suspects two American scientists of preparing a bio-terrorist attack against the United States President and order David and Caroline to investigate.

As the investigation continues on the suicides in Arkansas, the team believes it is a chemical release by worms that is the cause. Owen is charged with criminal negligence for the death by overdose of a school girl.

After an experimental treatment for Hep C nearly kills him, Wes quits NorBAC to enroll in a cutting edge HCV program in Stockholm; a racist city councilor claims his daughter was poisoned by Muslim extremists; the FDA is willing to fast-track some drugs in order to save an immune-deficient woman who was infected with smallpox.

NorBAC investigates an outbreak of prion disease (mad cow) in humans. The victims are spread out across North America. How are the cases connected? In the aftermath of Hiras's death, David is determined to expose the fraudulent reverend from episode 3. David suspects his old friend Danny, a hockey player, is using a dangerous performance-enhancing steroid.

A major power blackout on the Eastern Seaboard leads to fears of terrorist activity. NorBAC determines that a plastic eating bacterium caused the blackout and they must stop it before more blackouts occur. David and Lilith's mother, rekindle old animosities when she comes to town to help Lilith deal with Mick's death. Caroline is worried about the possibility of having breast cancer. Bob Melnikov, NorBAC's Biochemist tells David he has been approached with another job offer.

Mayko Tran, NorBAC's bioinformatics researcher, notifies the team at NorBAC about a case of privately contracted civilians who have all returned from Iraq exhibiting a wide range of mysterious illnesses. Meanwhile, Carlos asks NorBAC to investigate multiple cases of hemophilia in a small community in Mexico, where a large multi-national laboratory is working on GMOs. Jill must defend her reputation as a top virologist when a research paper she published is refuted.

NorBAC has been taken over by a joint command to deal with a catastrophic smallpox scenario. Bob tries to find a cure for his dog that is suffering from histiocytosis. Jill comes clean with David about taking medication for her panic attacks. David discovers that the earlier "Miranda Virus" outbreak might be linked to the U.S. government's secret bio-chemical lab and that whoever manufactured the "Miranda Virus" may possess another, even more lethal, biological weapon.

Carlos has disappeared for two days and David goes back to Mexico first to find Carlos and second help the Mexicans to fight the drug resistant TB that is killing tens of Mexicans in the region. Mayko and Rachel work non stop to find a cure to the TB and to find what is causing the inhabitants of Hudson Point, Illinois to be insensitive to pain.

NorBAC investigates a mysterious outbreak that is hospitalizing cyclists on the course of the Tour Cyclo Quebec. Meanwhile, Bob embarks on a controversial hyperbaric chamber treatment to deal with his brain infection and memory loss.

As the search continues for the source of the deadly prions, NorBAC zeros in on a large agribusiness they suspect of selling infected chickens. David tries to convince Danny to stop gene therapy. Caroline insists that David interview Jill Langston, for the vacated virologist position at NorBAC. His reluctance turns to lust when he meets her.

NorBAC reviews an experimental treatment being used on children with Leukemia. Just as they are about to declare the cancer therapy safe, another child dies. David disregards the proper channels and goes to Nunavut to get a sample of what he believes is the Spanish Flu virus from a frozen corpse. Mick and Lilith go whale-watching in Quebec, but Lilith begins to realize just how sick he is.