Magnus flies to a remote island in Africa to meet with the Sanctuary's new top secret advisor, but lands herself in the middle of a deadly hostage situation.

A quest to capture a legendary Abnormal in Bolivia leaves Will and Magnus injured and trapped in a cave-in, where they confront truths about themselves and their relationship. Henry records video letters to a special someone while working on an invention.

Abnormals in remote regions are subjected to an airborne biological agent that compels them to launch a violent string of murders

The Cabal's new "Super-Abnormals" begin destroying Sanctuaries around the world. It won't be long before they launch their attack on the Old City Sanctuary, and Magnus must choose between saving Ashley and saving the Sanctuary Network.

Investigating the disappearance of an old college friend, Will finds himself caught in an underground fight club where the combatants are genetically engineered abnormals who fight to the death like modern day gladiators.

A disoriented Magnus wakes up to find the Sanctuary in ruins and the entire city decimated, with no memory of how the devastation occurred. While surveying the destruction, she is attacked by an inhuman creature but saved by two armed men who stun her and take her to an abandoned warehouse. After being hosed down and left shivering and exhausted, Magnus fears the worst when a battle-scarred figure enters the room.

While transporting a usually docile abnormal, Magnus's helicopter crashes, leaving her and Will stranded in the shaft of an abandoned oil rig. They soon find they are not alone in the water.

Will runs into unexpected trouble and personal revelations on a trip to the Liberian Sanctuary in Monorovia. Meanwhile, Magnus has her hands full when a couple of ne'er-do-well flying Abnormals recruit her help with a questionable scheme.

A mysterious abnormal attacks Abby, and Magnus and Will discover there's only one way to communicate with this unusual enemy - through music.

The Five, led by Magnus, attempt to find the secret labyrinth in the decimated city of Bhalasaam. Once located, they must complete a series of cryptic tests that can only be achieved using each of their unique powers.

Word of a possible werewolf sighting prompts Henry and Will to visit an English psychiatric facility. As they probe a potential connection to Henry's Hyper Accelerated Protean past - and future - Magnus and Tesla investigate the mysterious holographic city.

As Will attempts to help Alexi cope with his abnormality, Helen gets a visitor from her past.

Dr. Helen Magnus, her daughter Ashley, and new to the Sanctuary, Dr. Will Zimmerman release three women from a mysterious crypt in Scotland, bringing them back to the Sanctuary for refuge. Unbeknown to the team, and the women themselves, they have extraordinary powers. And their disappearance does not go undetected by a powerful cabal, resolute on reclaiming what it determines is theirs.

An investigation into a string of bizarre robberies leads Magnus and Will to a crime ring of thieves who seem to be able to slip between the cracks of the law… literally.

Kate gains super-hero-like abilities when an Abnormal attaches itself to her for safe keeping.

Magnus responds to an anonymous call for help at an abandoned building. But when she gets trapped inside, she discovers whoever made the call has a very different agenda.

Will takes command of the Sanctuary while Magnus and Druitt search for a critical artifact in London. Knowing that Magnus's only hope for a cure lies in the secret subterranean city, Will ignores her warnings and releases Adam-Hyde in the hope that he will lead them to an access point for Hollow Earth.

Will and Henry's double date goes awry when Magnus tasks them with an Abnormal delivery.

With a government inspector threatening to cut off the Sanctuary's funding, Magnus and Will must explain a mission gone wrong. Meanwhile, Henry has a surprise visitor with some shocking news.

Just when Magnus thought Adam Worth was gone forever, she and Tesla become trapped in a virtual Sanctuary, where they are attacked by an avatar of Worth – who is determined to enter the “real” world.

Magnus and the Sanctuary team attempt to capture a rare and deadly creature - all under the watchful eye of a local news crew.

With chaos all around them, the team must come to terms with how to rebuild after the Cabal’s attacks. Magnus takes a methodical approach to prove Ashley is still alive, while Will and Henry take on the daunting task of processing the hundreds of Abnormals who now seek refuge at the Sanctuary.

A superhero is trapped by Magnus, and his lack of finesse affects the team's work. Elsewhere, Will and Declan go on the search for a creature that's loose in the city, after the discovery of an eggshell.

Dr. Helen Magnus fights to save the life of one of the Sanctuary’s research scientists who was viciously attacked by a seemingly docile Abnormal. Baffled by the creature’s uncharacteristic behavior, Henry tries to figure out what, or who, caused the domesticated Abnormal to react so violently.

The team goes on a routine mission to retrieve an Abnormal and take it to safety. But the mission becomes anything but routine when they are forced to stage a bank heist in order to protect the public from harm.