Grace may be able to tell God all the things she has done through her life because of her bond with Earl.

Grace Hanadarko is an Oklahoma City police detective with an alcohol problem and a self-destructive lifestyle. After she hits a man with her car while driving drunk, she asks God for help and an angel named Earl appears. Earl wants to help her find the right path of life again, but it is going to be a hard piece of work for both of them.

Grace and her team investigate the murder of an oilman. Meanwhile, Ham discovers Grace's romantic past with Butch Stillwater, which puts a strain on their relationship. Grace sets out to prove her courage by challenging Earl to a wrestling match.

A 17-year-old devout Christian comes under attack just days before he’s scheduled to testify in a murder trial. In order to ensure his safety, Grace allows him to move in with her. But Grace can only handle so much preaching, so she ropes the guys into helping her watch over him. Grace gets pissed when Earl uses Leon Cooley and her nephew, Clay, to get her attention.

Grace and her team investigate the murder of a manager of a sleazy local motel. The investigation eventually leads to a maid, who claims the victim was trying to rape her. Complications arise when a local priest offers her the right of sanctuary. Meanwhile, Grace begins to accept Earl's presence in her life.

A home for the mentally challenged is the target area of investigation when a robbery occurs involving a man with Down Syndrome.

Grace and Ham play cops and robbers with toy guns. Grace’s favorite Aunt Cathy comes to town – has a run in with Earl, clashes with Betty – and reveals some shocking news. But first-- Rhetta, Grace, and Aunt Cathy get drunk and remember old times. Meanwhile, cattle tycoon Alvin Green’s world begins to crumble after his lucky bull statue is stolen. He insists Major Crimes take the case. When Grace’s father has a fire station named after him, Grace’s family comes together for the dedication ceremony. Henry’s cat dies and Grace comforts him the only way she knows how.

Grace and the guys investigate the murder of a “crispy critter” in the Oklahoma countryside and Bobby soon discovers the deceased was one of his mentees. Grace enlists the help of her Native American grandfather, “Geepaw,” to help with the case, but is shocked when she sees how quickly his health is deteriorating. Grace and her sister, Paige, fight over many things, including Geepaw’s future in a nursing home. Earl tries to make Grace realize the importance of family… and Grace and Butch rekindle their passion.

Grace is called to the crime scene where there is blood everywhere but no body; Ham and his wife separate; a ketchup and mustard incident becomes a running joke around the squad room.

The team investigates a woman's death, while Grace seems captivated by the prime suspect, a high-profile architect and her unusual sex life. Meanwhile, Grace and Ham partner up once again, with hopes that their romance will be rekindled by the union. Elsewhere, Bobby's undercover case leads to an explosive conclusion, and Clay forms a bond with a young kid.

The squad's evidence supervisor is found dead in a bathroom stall at the local cop hang-out; Ham's brother comes to visit before being deployed; Grace and Leon dream about each other.

During a case that puts Grace’s spirituality to the test, the squad investigates the murder of a Hasidic Jew whose body is found near a herd of dead cows. Meanwhile, Grace tries to connect with Neely, and Ham’s sister-in-law, Amanda, struggles to get over the death of her husband.

Grace gets to see a new side of her nephew when a rock band is related to the murder case. Neely lives next door to Grace and begins withdrawal with help from Earl. Rhetta continues where she left off with Ronnie.

Everybody can't figure out why Capt. Perry seems to be on an edge all the time. Rhetta and Ronnie learn to communicate better since the start of their relationship with Johnny.

Grace has trouble dealing with a food issue and doesn't go to anybody for help to deal with it. Neely's having trouble when her drug problem spirals out of control. A friend of Butch's needs help getting out of a tough situation.

A mother goes missing; Clay joins the OCPD Explorers program against his father's wishes and confronts Ham about his affair with Grace; Butch becomes the target of a stalker.

Grace and her crew investigate the unusual suicide of a court reporter, and conclude the crime was staged. Elsewhere, Grace tries forming a bond with Neely, despite the fragile physical state of the young drug abuser; and Rhetta is close to losing something very special to her.

In the immediate aftermath of Grace and Neely’s survived fall from the top of a building, Grace, now known as “Angel Cop” by the city, decides to have it out with God once and for all. But a mysterious stranger might have something to say about that. Ham struggles with his father over the fact that Ham is now dating his dead brother’s widow. And the squad investigates a deadly mauling by a dog.

As Grace deals with the aftermath of her dramatic fall from a building with Neely, she also struggles with the impending death of her grandfather, GeePaw (guest star August Schellenberg). Meanwhile the squad investigates a double homicide involving a water dispute between two ranchers, and Rhetta discovers a secret about her daughter.

Grace must cope with survivor's guilt after a fall off a building. Captain Perry has an announcement that could change everything. The squad looks into a murder mystery.

A teenage girl dies at a school friend's party that Grace's niece was at; Grace has a new partner; Johnny tries to learn more about Earl.

The team blows Bobby's cover when they investigate a murder; Grace has suspicions about Abby; Rhetta and Johnny meet with Leon.

Grace ends up in the middle of what could be a plot by an anti-government group linked to the recent death of a police officer, as she reaches out to Neely, the young drug addict who shares visions of Earl. Grace's clumsy, off-the-books investigation causes Neely to become injured. Meanwhile, Grace and ham get caught in a compromising position, and Butch makes a surprise announcement.

A bomb explodes at the church run by Grace's brother,, making the case personal for her. Meanwhile, Rhetta is haunted by family problems, causing her to search for a family time capsule she and Grace buried as children. And, Grace keeps a watch at Neely's bedside.

A young Mexican woman dies at the hospital after being dropped off by a known white supremacist; Ham continues to struggle.