In 2017, Alisha Canales-McGuire is shot dead at her sister's house. Evidence points to a targeted attack, but detectives can find no reason why anyone would kill Alisha until CCTV and social media lead to a tangled murder plot.

In 2018, an explosion kills Anthony House on his doorstep; as police investigate, another bomb goes off, killing teen Draylen Mason; it becomes clear that Austin, Texas, is under attack from a serial bomber; police must use CCTV to track him down.

In 2021, talented high school football star KJ Taylor is killed during a drive-by shooting outside a West Virginia convenience store; CCTV helps detectives follow the trail of the truck spotted stalking KJ's friends leading up to the shooting.

In 2010, three men are murdered in a convenience store in Minneapolis's Somali community; the store's CCTV system uncovers evidence of a robbery gone wrong, and footage from cameras around the city could offer clues to the killer's identity.

A motorist shoots dead Whitney Gray while she shops with her young kids and teenage niece. Detectives follow a trail of CCTV to track down the suspect car and discover that the killer is on the run and carrying a stash of weapons.

In 2017, in San Diego, 28-year-old musician Omar Medina goes missing; his family's worst fears are confirmed when his body turns up in a barrel floating in the bay; police turn to surveillance footage to track down the people responsible.

In 2020, 21-year-old Dioneth Lopez goes missing while on a trip to visit friends; her body turns up in the woodlands of Washington State; she is treated as a Jane Doe until detectives find surveillance footage that pieces together her final hour.

Choir director Kathy Blair's son discovers her murdered at home; detectives find camera footage containing a shadowy figure that might just be their killer; the murder of a couple nearby sparks fears this might be the work of a serial killer.

Police investigate two murders with victims from very different worlds.

In 2018, three women held hostage in a motel room by armed men face a night of terror that leaves 19-year-old Amber Meadows lying dead in the bathroom; detectives must follow a trail of surveillance footage to find out who pulled the trigger.