After Dracula is released from his tomb in Transylvania, he decrees that all mortals will pay for his imprisonment. He brings the Wolfman and Frankenstein's Monster back to life and gives them powers with the ability to turn normal humans into monsters. Only Spider-Woman can stop the monsters and defeat Dracula before everyone becomes as horrific as them.

On Grand Cayman Island, worshippers of Dormammu the demon, summon him in a mystic ceremony. He tells his followers that he intends to expand his sphere of influence to the whole Earth, by stopping the Moon in its orbit while a total eclipse occurs in two days' time, causing the Earth to be forever covered in darkness. Jessica, Jeff and Billy journey to the island to cover the launch of a new satellite telescope that is to observe the eclipse. The satellite launches on schedule, but Dormammu and his followers take control of all the launch personnel. He orders them to guide the rocket towards the Moon in order to stop it. Jessica, immune to Dormammu's hypnosis, becomes Spider-Woman and disables his cult before the satellite hits the Moon. To stop Spider-Woman from interfering further, Dormammu kidnaps Jeff. Spider-Woman attempts to find out where Jeff has been taken, but is attacked by rock monsters. She defeats the monsters only to end up being trapped along with Jeff in a giant glass

Jessica, Jeff and Billy take a ride out into the countryside, where they spot a black U.F.O. travelling in the sky above them. Jeff and Billy look for help, while Jessica becomes Spider-Woman to save a country house and its inhabitants from the black rays of the U.F.O. After saving the people in the house, Jessica, Jeff and Billy travel to the Hawk Peak Observatory to talk to Professor Jansen in order to find out where the spaceship came from. They discover that the spaceship and many others came from the centre of a black hole. Spider-Woman attempts to stop the spaceship from covering New York with their black rays, but is unable to do anything from outside the ship. She secretly boards the ship, and discovers that the leader of the black hole aliens is called Graviton, and he intends to cover the whole Earth with their black hole rays in order to make it suitable for invasion. Spider-Woman battles Graviton and has to figure out a way to defeat him, and stop his entire fleet of spaces

A secret government-built time machine becomes the target of the renegade scientist Dr. T, but fortunately Jessica is on hand to become Spider-Woman and stops his evil plan. However, Dr. T manages to steal the plans to the time machine and eventually builds one of his own, to steal precious items from the past. He then travels a thousand years into the future and having found powerful warriors there, brings them back to the present to help him take over the world. Spider-Woman has to defeat the future warriors and return them to their own time, before hers runs out.

In Egypt, a new purple pyramid mysteriously rises from the desert. Spider-Man investigates the pyramid, only to discover that it is a sophisticated alien spaceship under the control of an alien mummy called Kufu from the planet Hotep. Meanwhile, while visiting a museum of Egyptology, Jessica and Jeff come under attack by a mummy contained in one of the exhibits. Jessica becomes Spider-Woman and saves Jeff, afterwards finding out that mummies in exhibits all over the world have been coming to life. She discovers that Spidey has been captured by the mummies' leader in Egypt. Jessica, Jeff and Billy travel to Egypt to follow up on reports of Spidey's capture. Kufu tells Spider-Man that he and his followers came to Earth thousands of years ago, awaiting the right time for colonisation of the planet, which has arrived. He tells Spidey that they will convert all of the Earth's inhabitants into mummies as well. Jeff and Billy enter the pyramid, where they fall into a quicksand trap. They are

The Drew Laboratories are infiltrated by a bionic midget(!), who attempts to steal Dr. Alexander Drew's secret research journal. Spider-Woman shows up and stops him getting away with the book. Unbeknownst to her however, the bionic midget took photographs of the notes within the book using his bionic eye. He takes the pictures to his boss, Dr. Hagell, who then plans to steal genetically cloned flies from the Government Research Foundation. After his midget assistant obtains the flies for him, Hagell experiments on himself and becomes a giant human fly. With his newfound abilities he decides to take revenge on his former colleagues for holding back his research. Spider-Woman does battle with the Fly back at her father's lab, but is unable to stop him getting away. After observing Spider-Woman's powers, the Fly reads Dr. Drew's journal and discovering that Drew's daughter Jessica was bitten by a dangerous cloned spider, he figures out that Jessica is Spider-Woman. He confronts Spider-Wom

A powerful magician known as the Great Magini performs a series of impressive magic tricks in front of a captivated audience, including Jessica, Jeff and Billy. During the performance, a valuable painting is stolen. Thanks to Jessica's spider-sense, she discovers that is was Magini himself who took the painting, and Spider-Woman quickly helps to bring him to justice. However, Magini escapes from the police and sets about performing his most audacious plan yet - to steal the great landmarks of the world, starting with Mount Rushmore. Spider-Woman eventually tracks him down to his magical house of horror, where she must survive his many traps in order to stop him.

Underneath the First National Bank in New York, the Kingpin and his henchmen tunnel their way into the vault. However, Spider-Woman quickly turns up to stop the Kingpin and his men. She is caught off guard and the Kingpin manages to escape with a million dollars. Jessica decides to devote the next edition of Justice Magazine to the Kingpin, which annoys him greatly. Hew decides to steal a new government-built invisibility ray in order to get revenge on Jessica Drew for writing derogatory remarks about him. Turning himself invisible, he infiltrates the Justice Magazine building and discovers that Jessica is Spider-Woman. She is soon contacted by the Kingpin, who tells her that he knows who she really is. He ambushes Spider-Woman with the help of the ray, and announces on television that Jessica Drew is Spider-Woman. With Spider-Woman still a captive, the Kingpin steals jewels from the International Jewellers Convention. Spider-Woman is left with the task of escaping confinement, saving

After an Air Force squadron disappears over the Bermuda Triangle, two more planes are dispatched to discover what happened, but they too disappear. Meanwhile, Jessica, Jeff and Billy visit the aircraft carrier in the vicinity of the Triangle after being granted an interview with the ship's commander. With the situation becoming more dangerous, the Justice Magazine crew is ordered to leave the area, but their jet-copter disappears like the jets, only to discover a hidden dimension containing a prehistoric-like island. Jessica and her team explore the island, and after Jessica becomes Spider-Woman to deal with some dinosaurs, discover a tribe of Neanderthals. They are using advanced technology and are under the control of Dr. Morrison, who discovered the island thirty years ago and is preparing to take over the Earth. Spider-Woman attempts to free Jeff and Billy from Morrison, but she too ends up as a captive along with the missing pilots. The doctor orders his cavemen to go to the Bermu

Deep in the Kongo jungle, the local tribesmen are attacked by a giant spider. Spider-Woman, who had been alerted by her spider sense, travels to the Kongo jungle and rescues the threatened locals from the spider. With everyone safe, she returns to the Justice Magazine building, not knowing that her battle with the giant spider was filmed by C.B. the director, who wants to make a movie starring both Spider-Man and Spider-Woman, and end their careers permanently in the process. Jessica's spider sense again alerts her to the giant spider's current rampage in the Kongo, and she Billy and Jeff go to Africa. Spider-Man too goes to seek out the giant Kongo spider after reading about Spider-Woman's exploits in the Daily Bugle. Jessica and the others are captured by the spider, but Spider-Man shows up to rescue them. Shortly afterwards, Spidey himself is captured and used as bait to lure Spider-Woman into the open. Jessica quickly changes and manages to rescue Spidey, but soon they are both cap

A recently launched space shuttle carrying astronauts and civilians (including Jessica, Jeff and Billy) is highjacked by the aptly-named villain Steeljaw. He takes the shuttle to his moon-base where he intends to use his kidnapped victims to dig for valuable moon gems. It falls to Spider-Woman to stop his evil plans.

Whilst in Scotland investigating recent sightings of the Loch Ness Monster, Jessica is forced to become Spider-Woman to deal with a race of human spiders. They observe her powers and abilities and believe her to be their Spider-Queen, having returned after many years. They alter her mind so that she will work with them and lead their forces into conquering mankind. Only Jeff and Billy can help Spider-Woman regain her memories.

Jessica, Jeff and Billy are covering the U.S. team for the World Athletic Games in Moscow. The plane carrying the team is attacked in mid-air by another craft, with the whole crew disabled by a knockout gas. One of the athletes is kidnapped and taken aboard another craft. Spider-Woman rescues the athlete, unaware that he has been replaced by an android duplicate. At the games in Moscow, Bruce Thompson, the kidnapped competitor, proceeds to break all pole vault records by performing with apparently super-human strength. A Russian athlete is the next to be kidnapped and replaced by an android, and he too proceeds to break all weight-lifting records. Jessica decides to enter the games herself as a long-jumper, in order to discover what happens to the missing individuals. She too, is kidnapped and replaced by a duplicate, but she manages to escape as Spider-Woman, and discovers that every country now has a representative android carrying a gold medal. It is the plan of master criminal Jacq

In the Arctic, the army retrieves a frozen spaceship, containing an alien. The alien is accidentally awoken by the soldiers, and introduces herself as Mumara. She instantly sets about to place everyone in the world into a deep sleep so that she can be sustained by their dreams. Luckily for Jessica, her spider-powers make her immune to Mumara sleep-inducing rays. However, in order to save everyone, Jessica becomes Spider-Woman and is left to enter the dream world to stop Mumara once and for all.

Fort Knox is raided by a group of Amazon warriors, who steal all the gold kept there. News of that, and other thefts by the Amazons reaches Justice Magazine, and Jessica, Jeff and Billy travel in the Justice jet-copter to the Amazon river. There they encounter the Amazon warriors, with Jeff and Billy being taken to their leader, Shanna, and Jessica as Spider-Woman following them to their hidden city of gold. She tries to free Jeff and Billy, but is forced by Shanna to lead her warriors in their final raid. Billy manages to free Jeff while Spider-Woman helps the Amazons to steal more gold for Shanna. When she returns to the hidden city, Shanna tells her that the stolen gold is to be used to construct a solar-powered device to take over the Earth. As Jessica, she disguises herself as one of the Amazons and frees Jeff and Billy. But it is Spider-Woman who is left with the task of stopping the Amazons' fleet and their solar laser.

Off the coast of Norway, a cruise ship is almost sucked into a whirlpool. With Jessica and her companions covering the Nobel Peace Prize conference in Stockholm, it isn't long before Spider-Woman arrives to save the ship. Afterwards, she discovers that the whirlpool was caused by a sunken Viking ship. The old ship is raised by the sea authorities, and the press are invited aboard. Billy finds an old treasure chest and puts it onto the deck of the ship, where Jeff opens it, releasing three malevolent Viking spirits. The journalists (including Jessica) are thrown into the sea. Soon Spider-Woman shows up and rescues them, before dealing with the Vikings and their ship. The Vikings' ship leaves Norway and after travelling to London, the Vikings begin to steal riches from the Tower of London. Jessica gets Jeff to fly them all to London, where she then confronts them as Spider-Woman. Unfortunately, she is captured and banished into the past, to the year 952 A.D., where she confronts more Vik