It's the holiday season at St. Denis. Alex and Ron care for a patient whose diagnosis is not what it seems. Joyce enlists Serena's help to boost St. Denis' online presence. Bruce and Matt help a Santa in need.

Joyce asks Alex to be the executor of her estate; Matt and Serena are forced to keep watch over a bickering family; Bruce grapples with unexpected DNA test results.

Joyce launces a women's health initiative to unexpected results; Ron treats a patient who has all the answers; Bruce has an existential crisis.

Ron mocks Alex and Matt's attempts to resolve a conflict between two prison inmates who stabbed each other in a gang fight. Serena helps Bruce address his fear of needles. Joyce finds herself smitten by the burly prison guard.

Joyce's belief that personal life should stay out of the workplace is tested by unexpected news. Ron thinks a patient has a crush on him. Bruce tries to demonstrate the value of his important work.

When Ron hexes the day to prove superstitions aren't real, things at the hospital start getting weird. Joyce and Matt discover an employee's secret.

Alex accidentally provokes the Emergency Department's mean girls. Ron and Serena battle over parking etiquette. Bruce has a hard time letting go of the spotlight.

Ron and Bruce butt heads over a candy bar. Alex is forced to fire an incompetent employee. Matt seeks appreciation for saving a patient's life.

An emotional support animal is loose in the halls of St. Denis; Alex goes big for Serena's birthday to mixed results.

An "intimacy in the workplace" discussion leads Joyce to discover she's out of the loop on office gossip; Alex gets self-conscious about her sex life; Bruce tries to fight a new policy about dating co-workers.

Ron's bedside manner earns him a complaint from a frustrated patient; Alex insists an unflattering online review was not about her; Bruce confronts his high-school bully.

Joyce pushes the staff to upsell patients on hospital procedures, kicking off some fierce competition and a case of mistaken identity; Bruce and Ron try to play plumber for a day.

Alex is torn between her daughter's school play and an "all-hands" situation in the Emergency Department. Joyce spends the hospital's limited funds on a fancy mammography machine. Matt's first day as a nurse isn't going as he'd hoped.

When a famous musician's performance at the hospital is delayed, Joyce throws an impromptu talent show with the St. Denis staff; Alex attempts to connect with her daughter, Ella.

Bruce and Alex give conflicting medical advice to a young athlete; Joyce competes with Tiger Woods in her alumni magazine; Matt and Serena (almost) drop an unconscious patient.

Ron's teasing makes Joyce question whether her friendship with a pharmaceutical rep is genuine; Alex has trouble letting Serena take on a new task; Matt finds a mentor in Bruce.

At the annual fundraiser, Alex and her husband, Tim, try to have a wild, kid-free night; Ron and Joyce butt heads over hosting duties; Bruce sets out to win this year's "Dancing with the Caregivers" competition.