Neil deGrasse Tyson interviews musician David Byrne and discusses creativity in the arts and sciences with co-host Maeve Higgins and guest Monica Lopez-Gonzalez.

Neil deGrasse Tyson interviews Mars One co-founder Bas Lansdorp and discusses the idea of establishing a permanent human settlement on Mars with co-host Eugene Mirman and guest Mike Massimino.

Neil deGrasse Tyson interviews David Crosby and discusses folk music and social justice with co-host Chuck Nice and guest Thomas Sugrue.

Neil deGrasse Tyson interviews physicist Brian Cox and discusses communicating science to the public with co-host Maeve Higgins and guest Jason Silva.

Neil deGrasse Tyson interviews Gina McCarthy and discusses the EPA's efforts in keeping the Earth habitable for humans with co-host Maeve Higgins and guest Andrew Revkin.

Neil deGrasse Tyson features his interview with Lance Armstrong and discusses the science of cycling with Scott Adsit, Max Glaskin, and Arthur Caplan.

Neil deGrasse Tyson features his interview with Kareem Abdul-Jabbar and discusses the science of basketball with Chuck Nice and Charles Liu.

Neil deGrasse Tyson features his interview with Jane Goodall and discusses chimpanzee behavior with Chuck Nice and Jill Pruetz.

Neil deGrasse Tyson features his interview with Katie Couric and discusses the intersection of science and journalism with Eugene Mirman and Jeff Jarvis.

Neil deGrasse Tyson features his interview with Kevin Smith and discusses science fiction and the science of superheroes with Chuck Nice and Charles Liu.

Host Neil deGrasse Tyson features his interview with former head of DARPA Arati Prabhakar.

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Neil deGrasse Tyson interviews Salman Rushdie and explores the science of storytelling with comedian Eugene Mirman and literary scholar Jonathan Gottschall.

Neil deGrasse Tyson features his interview with Mae Jemison and discusses the challenges of interstellar travel with Godfrey and Lawrence Krauss.

Neil deGrasse Tyson features his interview with Alan Alda and discusses science communication with Matt Kirshen and Heather Berlin.

Neil deGrasse Tyson features his interview with Stephen Colbert and discusses the intersection of science and comedy with Adam Conover and Sophia McClennen.

Host Neil deGrasse Tyson interviews author Margot Lee Shetterly ("Hidden Figures: The American Dream and the Untold Story of the Black Women Mathematicians Who Helped Win the Space Race") and actress Janelle Monáe, who starred in the movie.

Neil deGrasse Tyson interviews neuroscientist Sam Harris, and discusses everything from free will to religion with Godfrey and Andrew Newberg.

Neil deGrasse Tyson features his interview with puppeteer Frank Oz, then discusses puppets in pop culture and the people "behind the curtain" with Adam Conover and Charles Liu.

Neil deGrasse Tyson features his interview with surfer Kelly Slater, then discusses the science of surfing with Chuck Nice and William Finnegan.

Host Neil deGrasse Tyson features his interview with astronaut Scott Kelly.

Host Neil deGrasse Tyson interviews world-renowned physicist Stephen Hawking.