When two women die suddenly under mysterious circumstances, authorities initially suspect suicide. But both of their families believe it was murder, and are trying to figure out who is responsible.

A mother of two and a young woman planning a career in science both die under mysterious circumstances, and two families embark on quests for justice.

A family suspects foul play when their son drowns in a few inches of water.

He seems like a great partner. But when Susan Osborne and her 14-year-old son Evan disappear, it turns out "Mr. Right" has a secret. Then, when a young man is shot in a street confrontation, all clues point to one man. Could this case be that simple?

The murder-suicide of a mother and son may be something entirely different.

A 14-year-old boy vanishes, but neighbors don't tell police what they know.

A young woman on a trip to her father's homeland goes missing, then turns up brutally murdered. Another young mother and her baby are shot as they drive along a highway.

Someone snatches a baby boy from his crib, and a young mom goes missing.

A rookie police officer is heard confronting someone with a gun and is shot in the back of the head, but the D.A. believes it's suicide. And when a Navy veteran is discovered with wounds all over his body, police oddly think he died of pneumonia.

A young woman's body is found 200 miles from home, and a retired police detective uses his podcast to crowd-source the search for her killer. And, when a young mother disappears, an old answering machine message could hold the key to finding her murderer.

Eighteen-year-old Brookelyn Farthing disappears in 2013 after attending a party in Berea, Ky.; 24-year-old realtor Lindsay Buziak is found brutally killed after showing new clients a million-dollar home.

Thirteen-year-old Abby Williams and 14-year-old Libby German disappear while hiking on a popular trail; 13-year-old Dylan Redwine vanishes over Thanksgiving break while visiting his father in Vallecito, Colo.

Florida insurance agent Carla Stefaniak vanishes in Costa Rica; 19-year-old college student Pravin Varughese disappears after a party in 2014.

After a night out with friends, Jaleayah Davis, 20, is found dead; Kelsie Schelling, 21, drives two hours to show her boyfriend a sonogram of their baby, but never makes it home.

In Mobile, Ala., young mother Danniella Vian, 25, disappears into thin air; 19-year-old Holly Moore's suspicious death still raises questions four years after her body is found hanging in her closet

Their evenings begin as fun celebrations with friends but they end in murder. With disturbing evidence, terrifying theories, and demands for justice, can the mystery of how two young partygoers are murdered be solved?

A young Hollywood celebrity is out celebrating her birthday and another young woman enjoys a late drink with friends, just a few hours later, they both end up dead and investigators try to solve the mystery. 

Two young brides-to-be are just beginning to plan their weddings when their dreams are tragically cut short. Can desperate calls made to 911 reveal the truth about their shocking deaths?

When two young women vanish without a trace, investigators are haunted by the things they leave behind - a car with the keys still in the ignition, a pair of shoes, and a coat. They disappear with no warning. Where have they gone?

They are head over heels in love with their whole lives ahead still ahead of them, but then they die suddenly under suspicious circumstances. Could the strange text messages that come from their own phones hold the clues that investigators need?

Two young women who dream of big success as television anchors are just embarking on their careers when their plans come to a violent end. They are murdered in their own apartments and there are no signs of forced entry. Did they know their killers?

A respected police officer heads home after a late shift, and a young man who has just moved into his own place relaxes after watching football. How do these routine evenings turn deadly? Were their killings cold-blooded assassinations?

The murders of a teenage boy who never returns home from school and a teenage girl who is ambushed as she sits in a car with friends devastate their communities. It is every parent's worst nightmare - who would kill two innocent teenagers?

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They are the victims of shootings that seem senseless. Who would want them dead? Did these two young people get tangled up with the wrong crowds? And will anyone be held accountable for their murders?