The rest of the group from the Prison Planet have made it safely back to Beerus's planet, where they regroup with Whis. Xeno Goku and Xeno Vegeta return to their own universe, wishing the others good luck. Suddenly, the Supreme Kai of Universe 6 appears

Oren and Kamin suddenly convert their bodies into energy and possess Kale and Caulifla, using their bodies to attack the others. Vegeta, Trunks and Hit develop a plan; Trunks and Hit fight and immobilize Oren and Kamin, with the siblings forced to abandon their host bodies when Vegeta fires a Final Flash at them. Before the battle can continue, Hearts appears with a strange crystal and immobilizes all of them with his psychic powers.

Vegeta and Trunks arrive in Universe 11, and discover that Hearts and his gang are already there attacking. Oren catches the Saiyans off-guard and possesses Vegeta's body, gaining his immense power for himself. Trunks attacks Oren, but he is easily defeated. Meanwhile, Jiren is fighting Cumber: they appear to be evenly matched, so Cumber transforms into a Super Saiyan, but Jiren is still holding his own until Hearts appears and calls off the fight. Oren takes over fighting Jiren, while Hearts sends Cumber to attack Universe 3 instead. Kamin and Zamasu join the battle against Jiren; Trunks tries to help by attacking Zamasu, but Oren swiftly defeats him again. Just as Oren is about to finish off Trunks, Goku arrives with the Grand Minister. The Grand Minister departs, and Goku demonstrates that he now has some control over Ultra Instinct.

After freeing Vegeta's body from Oren's control, Goku confronts Hearts. Oren and Kamin attack Goku again, but he easily overpowers them both. Realizing that they can't beat Goku separately, the two fuse into "Kamioren" to take him on. Meanwhile, Jiren throws a massive energy blast at Zamasu, but Zamasu survives unscathed thanks to his immortality. As Goku is winning against Kamioren, Hearts uses his powers to launch a crystal from the Universe Seed at Goku. Unable to hold its shape under the pressure of Goku's and the Universe Seed's power, the crystal shatters and reveals a being called "Rags", the final member of Hearts's gang. Goku loses Ultra Instinct and reverts to his base form, exhausted by the effort of blocking the crystal. Rags then uses the broken pieces of the crytal to injure him, slicing him repeatedly and knocking him out. With Goku unconscious and unable to continue the fight, Vegeta powers up to his evolved form of Super Saiyan Blue and gets ready to fight Kamioren.

Vegeta begins fighting Kamioren, and seems to have the advantage. Rags attempts to finish off Goku, but Trunks intervenes and takes her on instead. Vegeta begins winning against Kamioren, and defeats them with a Final Flash that forces Kamin and Oren to separate. Meanwhile, Jiren continues to overpower Zamasu and injures him, but Zamasu's injuries quickly heal. Rags attacks Trunks with her crystals, but Goku knocks him out of the way and takes the attack himself. Hearts steps in and sends Rags to join Cumber in Universe 3, before confronting Goku himself. He reads Goku's mind and discerns that he hasn't perfected Ultra Instinct yet, but decides to try and draw out Goku's full power so that he can defeat him at his strongest. Goku, Trunks and Vegeta all attack Hearts, but he uses his psychic powers to immobilize them. Goku begins fighting to resist Hearts's powers, but Universe 7's Kaioshin suddenly appears and rescues the three Saiyans.

Hearts, Zamasu, Oren and Kamin arrive in Universe 7 to destroy it, but are confronted by Goku, Vegeta, Future Trunks, Android 17 and Piccolo. Oren and Kamin head for Vegeta, but are intercepted by 17 and Piccolo, while Vegeta and Trunks take on Zamasu. Goku repeatedly attempts to attack Hearts, but keeps getting pulled down by Hearts' gravity manipulation before he can get near him. Meanwhile, in Universe 3, Cooler, who is now a "Meta Cooler" cyborg, has defeated Rags and is fighting Cumber. After having some difficulty with Cumber's Super Saiyan form, Cooler transforms into his Golden form and overpowers Cumber; he begins charging up three Supernova attacks to end the battle, but his systems begin to overheat. Cooler launches the blasts, knocking Cumber out, but his overheating circuits are damaged and he is forced to retreat before he can finish Cumber off. Back in Universe 7, Oren and Kamin fuse into Kamioren and Hearts powers up as Goku stands up, ready to keep fighting.

After powering up, Hearts attacks Goku and their battle intensifies, with Hearts holding the advantage until Goku powers up to Super Saiyan Blue, after which they appear to be evenly matched. However, they both acknowledge that neither of them is fighting all-out yet. Goku is able to gain the upper hand and overpowers Hearts with a Kamehameha. Meanwhile, Trunks and Vegeta continue their battle with Zamasu, while 17 and Piccolo are able to catch Kamioren off guard, with 17 holding off their attacks while Piccolo charges up a Special Beam Cannon that wounds them. However, Kamioren regenerates and powers up wildly, enraged by the possibility that they could lose. Hearts gets back up and powers up again, using his control of gravity against Goku; Goku is able to withstand his attacks, so Hearts powers up even further.

After powering up, Hearts uses his crystals to further enhance his strength and defeats Goku with a single blow. Meanwhile, Piccolo and 17 are able to injure Kamioren again; Kamioren appears to be off-balance, so Hearts decides to assist them as the Universe Seed is finally ready. He shrinks the Universe Seed to a small size using his crystals and implants it into Kamioren, causing them to undergo a monstrous transformation that increases their power even further. In this state, Kamioren easily defeats Piccolo and 17, so Vegeta and Trunks go to assist them. All four fighters attack Kamioren together, but are unsuccessful. Kamioren is about to finish off Vegeta, but Goku goes to help him and is able to reach Ultra Instinct again, allowing him to withstand Kamioren's attacks.

Goku begins fighting Kamioren, and the two seem to be fairly evenly matched in terms of power, until Goku reaches the mastered level of Ultra Instinct and easily deflects Kamioren's attacks. He overwhelms Kamioren with help from the others, damaging them with a Kamehameha and a barrage of energy blasts before shattering their core with a final punch, causing their body to disintegrate. Goku loses his Ultra Instinct again, while Hearts expresses sorrow over the deaths of Kamin and Oren, before retrieving the now fully-charged Universe Seed from Kamioren's remains. Hearts begins absorbing the power of the Universe Seed, surrounding himself in a huge cloud of crystal cubes. Meanwhile, Zamasu looks on in satisfaction, but also seems to have his own agenda.

Vegeta and the others try to attack Hearts while he is absorbing the Universe Seed, but Zamasu stands in their way as he reveals that he is only aiding Hearts so he can resume his scheme without the Zenos' interference. Zamasu overpowers Goku after quickly incapacitating the others before Jiren and Hit arrive to join the fight, having been sent by their universes' Supreme Kais to deal with Hearts and his allies. Goku, Jiren and Hit are about to attack Zamasu again when Hearts suddenly emerges from his crystal construct, having assimilated the Universe Seed and its power into his body. Hearts uses his new power to easily immobilize Zamasu, then obliterates him after revealing that his goal is to destroy all the gods. The Grand Minister is disturbed from sensing Zamasu's death, as Hearts proclaims himself to be "the Godslayer."

Hearts launches a simultaneous attack on all of the Z-Fighters, who struggle to fight back. Goku powers up to Super Saiyan Blue and attacks him, but Hearts easily knocks him away and then uses a massive gravity attack to take down all of the fighters at once. As the others recover, Jiren and Hit go after Hearts again, while Goku suggests that he and Vegeta use the Fusion Dance to make themselves strong enough to take on Hearts' new power. Trunks, Piccolo and 17 rejoin the battle to buy time, while Goku and Vegeta perform the dance successfully and fuse into Gogeta. The other fighters stand down for the time being, as Gogeta prepares to battle Hearts.

Gogeta powers up to Super Saiyan Blue and launches an attack on Hearts. As the fight gets more intense Hearts powers up to his maximum as well, but Gogeta takes no damage and quickly gains the upper hand. Hearts then uses his powers to pull a gigantic meteor into the Earth's atmosphere, infusing it with his own energy before launching it at Gogeta. Gogeta powers up and prepares to stop the meteor.

Gogeta launches an energy blast at the meteor, slowing it down and temporarily holding it in place. Hearts uses his full strength and overpowers Gogeta's blast, propelling the meteor forwards again, so Gogeta powers up even more, charges up a Kamehameha and fires it at the meteor instead. Trunks is worried that the Earth will be destroyed, but Piccolo refuses to give up. Hit and Jiren join Gogeta and add their own blasts to the Kamehameha, increasing its power and ultimately shattering the meteor. Trunks, Piccolo and 17 shield the Earth from the meteor's fragments, while Gogeta and Hearts engage in a final clash. Gogeta overpowers Hearts and delivers a finishing blow that shatters the Universe Seed embedded in Hearts's chest, causing his body to disintegrate. As he dies, Hearts explains that he was merely trying to free all mortals by defeating the Omni-Kings, as their power to destroy entire universes on a whim prevents mortals from ever being truly free.