Will finds a car in the swamp, and attached are two married ghosts and their remains. The search for their killer, who just might be an old acquaintance of theirs, begins with the help of Will and the Swamp Thing.

A lunatic escapes from a local asylum and knocks on Tressa's door late at night. He proclaims himself as an alien killer. Even the Swamp Thing is in danger.

A mysterious couple search the swamp for the legendary Fountain of Youth. Arcane learns about the couple's plans and tries to find the Fountain first, as Will is caught in the middle of the couple's debate on whether or not the Fountain even exists.

Arcane accidentally creates a half-plant/half-robot with evil intentions from a mutated garden. The results are deadly to the swamp.

When Arcane unleashes a genetic assassin into the swamp in the form of a virus, he gets more than he bargained for; he not only gets rid of the Swamp Thing, but he accidentally brings Alec Holland back.

Arcane finally resurrects his wife Tatania, only to learn the woman is an impostor. A few hours in the lab with this woman leads Arcane to discover the true whereabouts of his beloved wife and the identity of her captor; General Sunderland.

Still fruitlessly searching for her missing son Jim, Tressa is diverted when she hears the voice of her former boyfriend, a radio jockey from the 70's. Tressa begins a second hunt for answers, as she discovers what really happened when her boyfriend disappeared 18 years ago, guided by his voice from the grave.

The Swamp Thing's worst enemy is also the enemy of the swamp...himself.

Graham leads a team of heavily armed mercenaries into the swamp to kill the Swamp Thing once and for all. Meanwhile, Tressa learns a few of the secrets of the swamp when she has a wounded visitor.

An old man has a deadly, infectious virus that only Alec's blood can cure. Arcane tries to exploit the disease for himself.

The ghosts of two temporally displaced Confederate Civil War soldiers appear in the swamp, one of whom is a previous resident of Will's house. The Swamp Thing assists Will to help the man to discover the mystery behind his wartime disappearance and make peace with his past.

A hunter and his son search the swamp for an endangered hawk. Their relationship is in shreds, and their conflict may prove deadly for Will, who has been adopted by the swamp to help protect the hawk.

Tressa's long-estranged sister returns looking for shelter from an enemy of her husband and ends up putting the Kipp house in danger, in the midst of a hurricane.

Will falls in love with a woman who claims to have known him in a past life.

Arcane, trapped in a cave with an unconscious Swamp Thing, launches into a monologue that sheds light on his motivations and (deep, enormous) neuroses.

Will is arrested for a murder that he did not commit.

The justice of the swamp comes in the form of a panther that stalks Arcane's compound. Arcane and his associates will be humbled one way or another, and the Swamp Thing can do nothing about it.

Dorian is an emotionally troubled teenager. He befriends Will, who begins to discover his troubled home life. Will and the Swamp Thing begin to try to help Dorian but there is one catch: Dorian could also be a vampire.

Arcane hosts a science conference, but it is crashed by a professional hit man who used to work for Sunderland and now has a score to settle. The Swamp Thing discovers the identity of the hit man and has a score to settle of his own.

When an elderly woman, named Irma Swanson, who knew and befriended the Swamp Thing, dies, her estranged daughter, Cathy, comes to town for her funeral. The Swamp Thing and the spirit of Irma then show Cathy the past of Irma’s troubled life in order for Cathy to make amends.

An experiment gone awry turns Arcane into a kind-hearted good guy and renders the Swamp Thing helpless and insane.

The Swamp Thing gets addicted to hallucinogenic iguana eggs which makes him live out a fantasy of being human again. His addictions almost cost Will his life when Arcane gets involved.

Sheriff Andrews allows Dr. Arcane to hunt an employee for sport. To teach Andrews a lesson, the Swamp Thing traps the corrupt sheriff in a fantasy of the Wild West populated by familiar faces, forcing him to duel the evil Renegade Jake in a fight to the death.

Arcane's genius mentor, Carl Mirador, has died. Using an experimental brain cell transfer, Arcane transfers all of Mirador's knowledge into his own brain. He also transfers Mirador's mental illnesses. Meanwhile, Will meets, and falls for, Mirador’s granddaughter, Dana.

Three convicts escape from prison in search of loot from a heist buried in the swamp. They soon discover they are not only being followed by the cops, but the Swamp Thing as well.