Jed pretends to be sick so that Granny can get to doctoring and feel more at home. Mr Drysdale and his physician, Dr. Clyburn get pulled into the ploy and Granny's mountain medicine is put to the test by a city doctor.

After Granny cuts off the top of Drysdale and Clyburn's (his doctor) hair for some homegrown remedy, Clyburn tries to keep her from ever doctoring again. Meanwhile, the Clampetts are looking forward to the Possum Day parade, which of course isn't celebrated in Beverly Hills, so Drysdale has to figure out how to have one to keep them happy. Granny also gives the men some of her hair growing potion.

Granny has everyone up at the crack of dawn to plow the front yard for her garden, while Mr. Drysdale, Miss Hathaway, and a stubborn mule try to stop her. Miss Jane takes Granny to a large Supermarket to show her how unnecessary it is to grow her own food.

Mrs. Drysdale recommends Elly for a high-brow finishing school in hopes that humiliating her will drive the Clampetts away; but instead Miss Hathaway convinces the girls at the school that Elly is a fashion trend-setter. Elly invites the filthy rich Fenwicks over, thinking they're destitute.

Cynthia Fenwick makes her filthy rich mother dress in the "Clampett Look" when they visit the Clampetts, since she thinks Elly is a fashion maven. That only reinforces the Clampett's belief that the Fenwicks are poor. Cynthia mistakes Jethro for royalty and Mrs. Fenwick mistakes Mrs. Drysdale for a cleaning woman.

An unemployed actor named J.D. Clampett and his wife benefit from a paperwork mixup at the bank, becoming $36 million richer. The Clampetts believe that Mr. Drysdale has forsaken them and taken the money. When Miss Jane figures out what has happened, Jake Clampett is arrested. Jed wants Jake freed as he might be kinfolk. Jake tries to pass himself off as a long lost cousin. Gil Perkins appears as the pool man.

Newly discovered "cousin" Jake Clampett soon has everyone but Jed thinking about and dressing for a role in a movie Jake wants to make. Mr. Drysdale hears that Jed is going to finance 10 million for the movie. Miss Jane comes up with a plan to put a stop to it all.

Mrs Drysdale wants an authentic Thanksgiving photograph, so she hires Pilgrim costumes, two Indian braves, & a live turkey for the picture. The turkey escapes into the Clampetts place & Elly makes a pet out of it. Granny wants to cook it, Jethro wants to eat it,and Jed just can't bring himself to kill it 'cause it keeps wanting to shake hands.!!

Mrs Drysdale is having a garden party & tells the Clampetts not to attend. They misunderstand & think she wants them to come. When they arrive they are bored so Mrs Drysdale sends them back next door to handle the Overflow crowd. Eventualy the whole party ends up at the Clampetts & they show these Beverley Hills folk how to have a real party.

Mr. Drysdale needs investors for his real estate development project, so he enlists the Widow Fenwick, and aims to cement the deal by hitching her to Jed Clampett, who is looking to find a mother for his daughter, Elly May.

Granny says they have no friends in Beverly Hills. Mrs. Schuyler-Potts expels Jethro from her school for being disruptive. Mrs. Drysdale wants to lock up all of Elly's critters. The Clampetts want to go back to the hills. Mr. Drysdale's efforts to prove to the Clampetts that Beverly Hills is really the place for them to be only makes matters worse.

A television, a boat, and a chimpanzee are among the many gifts Mr. Drysdale gives to the Clampetts for Christmas. Granny thinks the TV is some kind of fancy washing machine. Mr. Drysdale hopes that if the Clampetts enjoy the boat enough, they won't want to go back to the hills.

Granny's television idol, Western actor Quirt Manly, is revealed to be less than expected when he visits the mansion. Even though Granny is disappointed, Elly gets along with Quirt. Jed tries to help Quirt become more of a man's man.

At the mansion, the clan is in need of food, because the hunting in Beverly Hills is horrible. They call a catering company, but get mean-mouthed. At the bank, Drysdale gets a call and learns that he got a kangaroo from a friend and it is at his house. But the kangaroo gets out, and Granny sees it, thinking it is a giant jackrabbit. When she tells Jed, he thinks it is a vision from her jug. She never can seem to catch the creature, and whenever she tells someone, they don't believe her. She finally does, and when Beverly Caterers comes, Granny tells her to cook it, but it escapes from her rope, and runs back to the Drysdale place.

Some old love letters from Jethro lead mountain man Lafe Crick and his daughter Essiebelle to Beverly Hills. Jethro is looking forward to marrying Essiebelle until he sees how much weight she's gained. Essiebelle is not concerned as she loves a boy back in the hills. When Jed finds this out, he makes sure the wedding won't happen.

The freeloader Lafe Crick from back home takes advantage of Jed's charity and schemes to get rich off the Clampetts' wealth. Lafe manages to con Mr. Drysdale into giving him a job at the bank guarding Jed's money. But when he finds out that most of Jed's money isn't actually in the bank, Lafe then believes Jed has his money buried behind the mansion.

Mr. Drysdale would like Elly to run for Queen of Beverly Hills. The Clampetts think the race for the Queen is an actual foot race. So, Granny wants to run as well.

Lafe returns & talks Mr Drysdale into giving him a job as a nightwatchman at the bank to look after Jed's money. When Mr Drysdale tells Lafe that only some of the money is at the bank Lafe thinks the Clampett's have it buried in their backyard. He hurries back & pretends he's building Granny a root cellar, where in fact He's actually looking for their cash.

While Ellie continues to see Fred Penrod, Lafe Crick tries some match making with his son Dub and Ellie.

Granny's fear of boats only temporarily thwarts Mr. Drysdale's plan to take the Clampetts deep sea fishing, until he decides to take them to Marineland instead. Thinking that they're large fishing holes, Granny wants to "catch the whale".

Ellie has Dr. Martin of the zoo come over to treat her dog Duke who is sick. But Granny mistakes a bug repellent salesman Jim Gardner, who ends up falling for Ellie, for the veterinarian. Granny thinks he is no "Critter Doctor" but actually a "Bug Doctor" who is there to sell "bug vittles". Granny is taken with Dr. Martin, after finally meeting him.

Mr. Drysdale and Miss Jane help country musicians Lester Flatt and Earl Scruggs try to find a city woman for Jed the same way they found theirs, by holding auditions for backup singers.

Granny gets tired of the weather girl on TV saying that the weather is going to be clear when it is actually going to rain. She has a way to correct this, namely her weather beetle, Cecil. She confronts the head meteorologist of the U.S Weather Bureau but without luck. Jed goes down to speak to him and mentions the name "Daisy," making him think he means Hurricane Daisy, and tells of the plan to get rid of her.

Countess Maria comes to Beverly Hills, making Mrs. Drysdale very excited. But she wants to keep the countess away from the hillbillies. However, it's spring tonic time, and Granny passes it around the neighborhood, including at Countess Maria's house. She falls in love with the brew and visits the Clampetts. They become friends instantly. She starts falling for Jed, and has plans to marry her 6th husband, hoping it is an American.

Jed gets invited to the opening of Drysdale’s new Commerce Bank building. Granny thinks that he will actually be building the bank. Jed attends the party and meets two of Drysdale friends, who think he is a market wizard. When Jed is told he is helping to build the bank, he heads home to get tools and pick up Elly and Granny to help out. When they get there, they cause a bit of a disturbance and misunderstand what is going on.