In a life-altering competition, contestants use medically approved weight-loss techniques to shed pounds and try to win a $250,000 prize. The twelve players are seperated into teams - red and blue - and in the first challenge, pulling a heavy car across a track - the Blue Team prospers, but despite their advantage, the Blue Team also loses the least amount of weight at the weigh-in, and Dana becomes the first to be voted out.

After a tough elimination, the Blue Team gets back into the game on the second challenge, a bake-off which will determine the winner of a luxorious spa visit. The catch is that if any player takes a taste of anything they bake, 50 percent of all profits their team made is not counted. At the end of the task, the Red Team pulled through, making $362, edging out the Blue Team's $245. More importantly, the player's will power held strong, and no one took a lick of any food. At an emotional weigh-in, where neither Maurice, Lizzeth, Dave or Matt lose any weight, the Red Team is sent to the elimination ceremony, where Lizzeth is sent packing.

The Red Team and the Blue Team are forced to go onstage and perform about their feelings on their weight and weight-loss. The winner, decided by the audience at the nightclub which the players performed at, is the Red Team, who is given a reward. Later, even with the Blue Team training as hard as ever, the Red Team loses more weight than the Blue Team, forcing Blue to the elimination ceremony, where rumours and whispers divide their team. The deciding vote comes down to one of the Blue Team members, and Aaron is eliminated.

""Red and Blue Teams Go to New Heights"" - Blue Team trainer Bob Harper seems surprised after Aaron's ouster the night before. Things move on at the ranch, and after a workout, the players find a giant mountain of cupcakes in the house, with a note saying that whichever player eats the most cupcakes in 15 minutes would get to eat dinner with a loved one. After deciding on a method where no one would eat too many calories, Dave eats only one cupcake and is able to eat dinner with his wife, Tina. At the challenge, teams are forced to run up 1,500 steps to the top of a huge building. The Blue Team completes it more quickly than the Red Team, and are given a great reward. After a spat between Lisa and Jillian about effort, the weigh-in reveals that the Blue Team had lost more weight than the Red Team, and in the end, the Red Team chooses to send home Matt because of his failure to work with the team.

""A Team Lightens Up Through Elimination"" - After Matt's elimination Ryan realizes that Dave has been lying to him and the girls of the Red Team for the entire game. The challenge of the week is a food stacking competition - where team members must build their stack the highest using only their mouths and they may not eat any of the food during the game. The Red Team emerges victorious, giving them an amazing reward. However, the Blue Team comes out as the biggest winners; Andrea's 7-pound loss pushes their team to victory at the weigh-in, eventually leading to the Red Team eliminating the team member that is most annoying: Dave.

""Teams Trek to the Beach for a Challenge"" Rumours and suspicions fly after a tense previous elimination, where the women in the house assumed that the men were trying to pick them off. Players are just starting to get on each other's nerves: Maurice's lack of work ethic angers his team - and his trainer, Kelly Mac's backhanded compliments annoy the Red Team, and Lisa's whining continues to get on everyone's nerves. At the challenge, an agility competition meant to mimic lifegaurding, the Red Team prospers, winning themselves a trip to the Umberto Salon, where they receive makeovers and new hairstyles. The Blue Team, forced to vote one of their own off of the ranch, cannot decide who to eliminate. With a deadlocked vote, the members of the Red Team must choose to eliminate one of the members of the Blue Team, finally deciding on Kelly Mac.

""Biking Challenge"" Contestants race to log the most miles on a stationary bike before midnight, with a prize of better-fitting clothes as an incentive; participants learn of a new twist in the game.

The contestants are given an overwhelming surprise when they come face-to-face with their old, bigger, selves - cardboard cutouts as they apperaed the first day they arrived. The players run around a track with a weighted vest carrying the weight that each has lost so far. Ryan comes closest to his time from a previous run, winning himself immunity. At the weigh-in, Maurice and Lisa find themselves eligible for elimination, and when the other players vote, Ryan betrays his pinky promise with Lisa by being the swing vote for her ticket out of the house.

""A Lighter Side"" An often-comic look at the first eight episodes; previously unseen footage of contestants' exit interviews; bloopers; the contestants who cheated when they thought the cameras were out of range.

""Final Weigh-In at the Ranch"" It's payback time as the contestants turn the tables and ""train"" the trainers. This episode is the final weigh in at the ranch, preceded by the contestants reflecting on this journey that has changed their lives, and followed by a vote to trim the players' numbers down to three.

After weeks of training and careful eating tactics, the ""Biggest Loser"" is finally chosen, as the season finale comes about. The winner is decided during a live portion of the episode.

In this post-finale special, viewers discover more about the contestants' lives and competitive drive, including that of the Biggest Loser. Another weigh-in will take place, and one of the nine remaining contestants (less than third place) will win $100,000.

Caroline Rhea returns to welcome fourteen new players to The Biggest Loser and to host them at their stay at the new ranch. After being faced with a room of tempting food, the players discover a twist in the game - this time it's men vs. women! The women, who will always wear Red, will be trained by Jillian Michaels, while the Blue team, the men, will be put to the test by Bob Harper. Later, the new teams compete in the first challenge of the season - a competition that takes place in a jet so that the contestants can experience what it feels like to weigh nothing! At the end of this 90-minute episode, one of the hopefuls will be voted off of their team. Who will survive the battle of the sexes Biggest Loser style?

The contestants' diets are put to the test when they are told that if they eat some high-calorie treats, they will be given a letter from home. Who will be able to resist the temptation? Plus, who will win the next challenge, which deals with balance, and who will be voted off of their team?

Twelve contestants remain, as they continue to endure the pain from their injuries and the disputes from their trainers. They'll have to decide whether to continue on with the next physical challenge and resist the food temptations that continue to tempt them. Can they do it?

When the teams get a chance to go to Las Vegas, they'll have to endure some very tempting temptations. They will have to make some very tough decisions while they're there. Will they be able to resist, or will they lose it all for some cash?

As the teams continue to lose teammates, one team begins to lose their confidence. So, their trainer brings in a special visitor from the past to talk to them and help them regain their confidence once again. But will this be enough to get the team back on track, or will the team continue to fall apart, despite their trainer's efforts?

Because of the Blue Team's subpar performance on previous weekly challenges, the team decides to push themselves during workouts, as well as try harder to get along with each other. Meanwhile, Jillian pushes her team to go on their most dangerous workout yet. Can they handle it?

As eight contestants remain, everything changes with twists at every corner. The teams are no more, contestants are forced to work with their enemies, and even the weigh-in will have a special twist this time around. All this leads up to the most shocking elimination yet. Who will it be?

In order to participate in a professional photo shoot, all seven remaining contestants receive a Beverly Hills-style make-over. Afterwards, a special surprise awaits the seven contestants at the pedicab race when their family members arrive for a surprise visit, as they become the cargo for the race. The winner will not only receive immunity for the week, but he/she will also get to spend an evening with their family.

Caroline informs the remaining six contestants that the duos are gone from here on out. Now, they will all be competing against each other by themselves. Aside from this change in the game, one contestant will shock everyone with their new look. Meanwhile, two other contestants will end up having a fight between each other.

Before participating in the weekly challenge, the remaining men share their dreams with everyone else. This week, the challenge will prove to be one of the hardest ones yet. The contestants must hang on with their arms and legs to a tube hanging above a swimming pool. Can the remaining five contestants handle it?

Final episode before the live season finale, where the remaining four contestants discover how far they've come since their first day on the ranch. Time for one last challenge, in which the contestants will have to carry their weight in quarters, with the winner getting to keep his/her quarters.

Caroline Rhea hosts the live season finale, where ""The Biggest Loser"" will be chosen out of the three remaining contestants. The results of all their hard work will finally be revealed, with ""The Biggest Loser"" also walking away with $250,000, as well as a healthier lifestyle.

Caroline Rhea is back to host The Biggest Loser's third season! This time, 50 contestants will be chosen - one from each state in the U.S. There will be new surprises awaiting them, including the introduction of the new Red Team trainer - Kim Lyons. The contestants will soon learn that only 14 of them will get to stay at the ranch, sending the remaining 36 back home to compete on their own, with a chance of returning to the ranch to win the $250,000 grand prize.